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Nat Commun
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kinase inhibitor library screen (pkis, 221 kinases) with tnf-promoter luciferase reporter
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hoxb8-derived macrophages (pyk2 ko, irf5 ko)
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1 matching publication(s)
Defactinib inhibits PYK2 phosphorylation of IRF5 and reduces intestinal inflammation.
PMID 34795257 · Nat Commun · 2021
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