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Integrated multi-omics analysis combined with clinical validation reveals that HLA-DRB5 and ODAPH are causal risk genes for keratoconus.
PMID 41803193 · Sci Rep · 2026
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Integrative analysis of transcriptomic data reveals a predictive gene signature for chemoradiotherapy response in rectal cancer.
PMID 41550766 · iScience · 2025
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Liver-specific paraoxonase-1 alleviates regulatory T cell-driven immunosuppression via metabolic reprogramming in hepatocellular carcinoma.
PMID 41387425 · Nat Commun · 2025
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Advances in genomic and pharmacokinetic profiling for clinical stratification of metastatic breast cancer.
PMID 41369820 · Discov Oncol · 2025
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Blood and tissue correlates of steroid non-response in checkpoint inhibition-induced immune-related adverse events.
PMID 41254329 · Commun Med (Lond) · 2025
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Spatial-reprogramming derived GPNMB+ macrophages interact with COL6A3+ fibroblasts to enhance vascular fibrosis in
PMID 41174767 · Genome Med · 2025
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Interpretable artificial intelligence based on immunoregulation-related genes predicts prognosis and immunotherapy response in lung adenocarcinoma.
PMID 41048340 · Front Bioinform · 2025
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Positive Relationships between Intraocular Pressure and Thyroid Function in Graves' Ophthalmopathy: A Three-Aspect Evidence Analysis.
PMID 40992768 · Yonsei Med J · 2025
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Targeted and personalized immunotherapy in lung adenocarcinoma: single-cell RNA sequencing of MAFF+ tumor cells and the therapeutic potential
PMID 40936936 · Front Immunol · 2025
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Molecular subtype of recurrent implantation failure reveals distinct endometrial etiology of female infertility.
PMID 40660214 · J Transl Med · 2025
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Comprehensive bioinformatics analysis and experimental verification identify mitochondrial gene Dgat2 as a novel therapeutic biomarker for myocardial ischemia-r
PMID 40510478 · Front Endocrinol (Lausanne) · 2025
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Integrating multi-omics data reveals the antitumor role and clinical benefits of gamma-delta T cells in triple-negative breast cancer.
PMID 40197136 · BMC Cancer · 2025
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IRSN-23 gene diagnosis enhances breast cancer subtype classification and predicts response to neoadjuvant chemotherapy: new validation analyses.
PMID 40128415 · Breast Cancer · 2025
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Identification and validation of a metabolic-related gene risk model predicting the prognosis of lung, colon, and breast cancers.
PMID 39779736 · Sci Rep · 2025
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Differential bone morphology and hypoxia activity in skeletal metastases of ER+ and ER- breast cancer.
PMID 39572705 · Commun Biol · 2024
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A platelet-related signature for predicting the prognosis and immunotherapy benefit in bladder cancer based on machine learning combinations.⚑
PMID 39280688 · Transl Androl Urol · 2024
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Integrated drug resistance and leukemic stemness gene-expression scores predict outcomes in large cohort of over 3500 AML patients from 10 trials.
PMID 39090192 · NPJ Precis Oncol · 2024
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Neoadjuvant sintilimab plus chemotherapy in EGFR-mutant NSCLC: Phase 2 trial interim results (NEOTIDE/CTONG2104).
PMID 38897205 · Cell Rep Med · 2024
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The molecular landscape of sepsis severity in infants: enhanced coagulation, innate immunity, and T cell repression.
PMID 38817614 · Front Immunol · 2024
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Developing a novel immune infiltration-associated mitophagy prediction model for amyotrophic lateral sclerosis using bioinformatics strategies.
PMID 38601155 · Front Immunol · 2024
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Integrated multiomic analysis reveals disulfidptosis subtypes in glioblastoma: implications for immunotherapy, targeted therapy, and chemotherapy.
PMID 38504986 · Front Immunol · 2024
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Machine Learning-Based Integrated Analysis of PANoptosis Patterns in Acute Myeloid Leukemia Reveals a Signature Predicting Survival and Immunotherapy.
PMID 38322112 · Int J Clin Pract · 2024
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Assessment tool based on fatty acid metabolic signatures for predicting the prognosis and treatment response in bladder cancer.
PMID 38076064 · Heliyon · 2023
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Application of Machine Learning in Predicting Hepatic Metastasis or Primary Site in Gastroenteropancreatic Neuroendocrine Tumors.⚑
PMID 37887568 · Curr Oncol · 2023
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A urine extracellular vesicle lncRNA classifier for high-grade prostate cancer and increased risk of progression: A multi-center study.⚑
PMID 37852185 · Cell Rep Med · 2023
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Zebrafish functional xenograft vasculature platform identifies PF-502 as a durable vasculature normalization drug.
PMID 37680473 · iScience · 2023
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Identification of common genetic characteristics of rheumatoid arthritis and major depressive disorder by bioinformatics analysis and machine learning.⚑
PMID 37415981 · Front Immunol · 2023
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Clinical and molecular correlation defines activity of physiological pathways in life-sustaining kidney xenotransplantation.
PMID 37311769 · Nat Commun · 2023
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Comprehensive analysis of mitophagy in HPV-related head and neck squamous cell carcinoma.
PMID 37161060 · Sci Rep · 2023
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Artificial intelligence-guided discovery of gastric cancer continuum.
PMID 36692601 · Gastric Cancer · 2023
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Identification of intrinsic genes across general hypertension, hypertension with left ventricular remodeling, and uncontrolled hypertension.
PMID 36277786 · Front Cardiovasc Med · 2022
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Identifying Molecular Subtypes and 6-Gene Prognostic Signature Based on Hypoxia for Optimizing Targeted Therapies in Non-Small Cell Lung Cancer.
PMID 35509605 · Int J Gen Med · 2022
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Predicting Bone Metastasis Using Gene Expression-Based Machine Learning Models.
PMID 34858485 · Front Genet · 2021
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Gene Set Enrichment Analysis Reveals Individual Variability in Host Responses in Tuberculosis Patients.
PMID 34421903 · Front Immunol · 2021
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Construction and Validation of an Immune Infiltration-Related Gene Signature for the Prediction of Prognosis and Therapeutic Response in Breast Cancer.⚑
PMID 33986754 · Front Immunol · 2021
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Circulating mucosal-associated invariant T cells identify patients responding to anti-PD-1 therapy.
PMID 33723257 · Nat Commun · 2021
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Prediction of prognostic signatures in triple-negative breast cancer based on the differential expression analysis via NanoString nCounter immune panel.
PMID 33138797 · BMC Cancer · 2020
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Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing.
PMID 31443728 · Genome Med · 2019
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