Nicholas Schwab
Reproducibility track record
1
assessed papers
78/100
mean reproducibility
1
reproduced (C1–C2)
0
flagged
0
total citations
flag rate:
0%
(0/1)
The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.
Authorship role
first author: 0
last author: 0
Topics
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Funders
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Frequent co-authors
Tara R. Bradstreet 1Prabhakar S. Andhey 1Joseph J. Sabatino 1Nada M. Abdalla 1Brian T. Edelson 1Gregory F. Wu 1Ekaterina Esaulova 1М. В. Терехова 1Gerd Meyer zu Hörste 1Elizabeth A. Schwarzkopf 1
Institutions
Barrow Neurological Institute 1Washington University in St. Louis 1Neurosciences Institute 1Regeneron (United States) 1University Hospital Münster 1VA St. Louis Health Care System 1
Geography (author institutions)
US 1DE 1
Co-author network
Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.
How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.
Assessed papers (1)
Complete publication record (127)
Request a reproduction →1 assessed by us (1 reproduced) · 126 not yet assessed — every PubMed paper on record, linked below.
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TCR and BCR data supporting the findings of the manuscript "Confined B-cell reconstruction and high T-cell clonality define clinical response to cladribine treatment" by Schneider-Hohendorf et al. 2026 ↗Zenodo (CERN European Organization for Nuclear Research) · 2026not yet assessed
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TCR data supporting the manuscript "T-cell receptor analysis in monozygotic twins discordant for multiple sclerosis: genetic determinants and MS-associated signatures" by Li et al. 2026 ↗Zenodo (CERN European Organization for Nuclear Research) · 2026not yet assessed
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TCR data supporting the manuscript "T-cell receptor analysis in monozygotic twins discordant for multiple sclerosis: genetic determinants and MS-associated signatures" by Li et al. 2026 ↗Zenodo (CERN European Organization for Nuclear Research) · 2026not yet assessed
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Additional file 1 of Single-cell analysis of skin and blood reveals systemic immune responses to ultraviolet B and their impairment in MS ↗Figshare · 2026not yet assessed
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Additional file 2 of Single-cell analysis of skin and blood reveals systemic immune responses to ultraviolet B and their impairment in MS ↗Figshare · 2026not yet assessed
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Additional file 2 of Single-cell analysis of skin and blood reveals systemic immune responses to ultraviolet B and their impairment in MS ↗Figshare · 2026not yet assessed
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Single-cell analysis of skin and blood reveals systemic immune responses to ultraviolet B and their impairment in MS ↗Figshare · 2026not yet assessed
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Single-cell analysis of skin and blood reveals systemic immune responses to ultraviolet B and their impairment in MS ↗Figshare · 2026not yet assessed
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Additional file 1 of Single-cell analysis of skin and blood reveals systemic immune responses to ultraviolet B and their impairment in MS ↗Figshare · 2026not yet assessed
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Quelques lépiotes intéressantes ou nouvelles (Agaricaceae, tribu Leucocoprineae) observées dans une serre tropicale en FranceHAL (Le Centre pour la Communication Scientifique Directe) · 2026not yet assessed
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A single-cell compendium of human cerebrospinal fluid identifies disease-associated immune cell populationsJournal of Clinical Investigation · 2025 · PMID 39744938L1 78/100
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Prognostic Factors for Multiple Sclerosis Symptoms in Radiologically Isolated Syndrome ↗JAMA Neurology · 2025 · PMID 40455494not yet assessed
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HLA-A∗03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysis ↗EBioMedicine · 2025 · PMID 40749525not yet assessed
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B- and T cell receptor sequencing elucidates characteristics of lymphocyte depletion by ocrelizumab ↗iScience · 2025 · PMID 40727939not yet assessed
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AhR signaling in skin-resident CD207 <sup>+</sup> cells is involved in UV-B-induced amelioration of neuroinflammation ↗Proceedings of the National Academy of Sciences · 2025 · PMID 40892929not yet assessed
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Annual 12‐Week Dosing Gap of Natalizumab: Clinical Efficacy, Blood Biomarkers, and <scp>CSF</scp> Cell Composition ↗Annals of Clinical and Translational Neurology · 2025 · PMID 40988462not yet assessed
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Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories ↗Science Translational Medicine · 2024 · PMID 38536936not yet assessed
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Broader anti-EBV TCR repertoire in multiple sclerosis: disease specificity and treatment modulation ↗Brain · 2024 · PMID 39021292not yet assessed
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COMPARATIVE ANALYSIS OF T CELL EXPANSION BY BIOREACTOR TYPE: IMPACTS ON PROCESS METRICS AND CELL QUALITY ↗Cytotherapy · 2024not yet assessed
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Transcriptomics reveals CSF cellular composition in multiple sclerosis but detects no viral RNA ↗Brain · 2024 · PMID 38181428not yet assessed
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Single-cell profiling reveals preferential reduction of memory B cell subsets in cladribine patients that correlates with treatment response ↗Therapeutic Advances in Neurological Disorders · 2023 · PMID 38084102not yet assessed
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Learning CNS immunopathology from therapeutic interventions ↗Science Translational Medicine · 2023 · PMID 37939164not yet assessed
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Identification of multiple sclerosis endophenotypes by high dimensional blood signatures associated with distinct disease trajectories (P1-3.008) ↗Neurology · 2023not yet assessed
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A single-cell analysis framework allows for characterization of CSF leukocytes and their tissue of origin in multiple sclerosis ↗Science Translational Medicine · 2022 · PMID 36449599not yet assessed
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Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis ↗The Journal of Experimental Medicine · 2022 · PMID 36048016not yet assessed
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Alemtuzumab-induced immune phenotype and repertoire changes: implications for secondary autoimmunity ↗Brain · 2022 · PMID 35661859not yet assessed
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Increased Intrathecal Activity of Follicular Helper T Cells in Patients With Relapsing-Remitting Multiple Sclerosis ↗Neurology Neuroimmunology & Neuroinflammation · 2022 · PMID 35835563not yet assessed
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Enhanced pathogenicity of Th17 cells due to natalizumab treatment: Implications for MS disease rebound ↗Proceedings of the National Academy of Sciences · 2022 · PMID 36574650not yet assessed
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Progressive multifocal leukoencephalopathy genetic risk variants for pharmacovigilance of immunosuppressant therapies ↗Frontiers in Neurology · 2022 · PMID 36588876not yet assessed
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Data Sharing and Reuse: A Method by the AIRR Community ↗Methods in molecular biology · 2022 · PMID 35622339not yet assessed
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Effects of Latitude and Sunlight on Multiple Sclerosis Severity ↗Neurology · 2022 · PMID 35410911not yet assessed
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Correction: Broader Epstein–Barr virus–specific T cell receptor repertoire in patients with multiple sclerosis ↗The Journal of Experimental Medicine · 2022 · PMID 36305889not yet assessed
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The Future of Blood Testing Is the Immunome ↗Frontiers in Immunology · 2021 · PMID 33790897not yet assessed
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Classification of neurological diseases using multi-dimensional CSF analysis ↗Brain · 2021 · PMID 33848319not yet assessed
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Dimethyl fumarate treatment restrains the antioxidative capacity of T cells to control autoimmunity ↗Brain · 2021 · PMID 34849598not yet assessed
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Failed reproduction attempt by Biogen due to changed protocols, method of analysis, and poor biomaterial quality2021not yet assessed
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National Research Data Infrastructure for Immunology (NFDI4Immuno) ↗Zenodo (CERN European Organization for Nuclear Research) · 2021not yet assessed
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Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity ↗Proceedings of the National Academy of Sciences · 2020 · PMID 33376202not yet assessed
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Next-Generation Neuroimmunology: New Technologies to Understand Central Nervous System Autoimmunity ↗Trends in Immunology · 2020 · PMID 32147112not yet assessed
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MCAM/CD146 Signaling via PLCγ1 Leads to Activation of β1-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration ↗Frontiers in Immunology · 2020 · PMID 33381120not yet assessed
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High anti-JCPyV serum titers coincide with high CSF cell counts in RRMS patients ↗Multiple Sclerosis Journal · 2020 · PMID 33150829not yet assessed
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Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity ↗medRxiv · 2020not yet assessed
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Author response: Prospective validation of the PML risk biomarker <scp>l</scp> -selectin and influence of natalizumab extended intervals ↗Neurology · 2020 · PMID 32934158not yet assessed
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National Research Data Infrastructure for Adaptive Immune Receptor Repertoires (NFDI4AIRR) ↗Zenodo (CERN European Organization for Nuclear Research) · 2020not yet assessed
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Dimethyl fumarate treatment alters T cell metabolism in multiple sclerosis (1142) ↗Neurology · 2020not yet assessed
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Characterization of T cells in NMOSD patients - an emerging role for T cells in disease pathogenesis (4017) ↗Neurology · 2020not yet assessed
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CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome ↗Nature Communications · 2019 · PMID 31852955not yet assessed
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Teriflunomide treatment for multiple sclerosis modulates T cell mitochondrial respiration with affinity-dependent effects ↗Science Translational Medicine · 2019 · PMID 31043571not yet assessed
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Risks and risk management in modern multiple sclerosis immunotherapeutic treatment ↗Therapeutic Advances in Neurological Disorders · 2019 · PMID 30967901not yet assessed
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Natalizumab-associated progressive multifocal leukoencephalopathy in Germany ↗Neurology · 2019 · PMID 30952796not yet assessed
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Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis ↗Brain · 2019 · PMID 31563951not yet assessed
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Ineffective treatment of PML with pembrolizumab ↗Neurology Neuroimmunology & Neuroinflammation · 2019 · PMID 31597692not yet assessed
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VLA-2 blockade <i>in vivo</i> by vatelizumab induces CD4+FoxP3+ regulatory T cells ↗International Immunology · 2019 · PMID 30783682not yet assessed
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Extensive immune reconstitution inflammatory syndrome in Fingolimod-associated PML: a case report with 7 Tesla MRI data ↗BMC Neurology · 2019 · PMID 31399069not yet assessed
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Prospective validation of the PML risk biomarker <scp>l</scp> -selectin and influence of natalizumab extended intervals ↗Neurology · 2019 · PMID 31439633not yet assessed
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Myalgia with the presence of pathologic EMG correlates with perimysial inflammatory infiltrates ↗Neurology Neuroimmunology & Neuroinflammation · 2019 · PMID 41882911not yet assessed
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Re:Time to audit all reported PML cases2019not yet assessed
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Extensive immune reconstitution inflammatory syndrome in Fingolimod-associated PML: a case report with 7 Tesla MRI data ↗Research Square · 2019not yet assessed
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Extensive immune reconstitution inflammatory syndrome in Fingolimod-associated PML: a case report with 7 Tesla MRI data ↗Research Square · 2019not yet assessed
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Dietary salt promotes ischemic brain injury and is associated with parenchymal migrasome formation ↗PLoS ONE · 2018 · PMID 30589884not yet assessed
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Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus ↗Journal of Neuroinflammation · 2018 · PMID 30134924not yet assessed
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Sex bias in MHC I-associated shaping of the adaptive immune system ↗Proceedings of the National Academy of Sciences · 2018 · PMID 29440397not yet assessed
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Immune Cell Profiling During Switching from Natalizumab to Fingolimod Reveals Differential Effects on Systemic Immune-Regulatory Networks and on Trafficking of Non-T Cell Populations into the Cerebrospinal Fluid—Results from the ToFingo Successor Study ↗Frontiers in Immunology · 2018 · PMID 30050529not yet assessed
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Does the environment influence multiple sclerosis pathogenesis via UVB light and/or induction of vitamin D? ↗Journal of Neuroimmunology · 2018 · PMID 29793727not yet assessed
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Natalizumab-associated PML ↗Neurology · 2017 · PMID 28228564not yet assessed
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Liver X receptor activation promotes differentiation of regulatory T cells ↗PLoS ONE · 2017 · PMID 28926619not yet assessed
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Chemokine CCL17 is expressed by dendritic cells in the CNS during experimental autoimmune encephalomyelitis and promotes pathogenesis of disease ↗Brain Behavior and Immunity · 2017 · PMID 28642092not yet assessed
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Anti-JCV serology during natalizumab treatment: Review and meta-analysis of 17 independent patient cohorts analyzing anti-John Cunningham polyoma virus sero-conversion rates under natalizumab treatment and differences between technical and biological sero-converters ↗Multiple Sclerosis Journal · 2017 · PMID 28847222not yet assessed
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Single-cell profiling reveals GPCR heterogeneity and functional patterning during neuroinflammation ↗JCI Insight · 2017 · PMID 28768912not yet assessed
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Dual action by fumaric acid esters synergistically reduces adhesion to human endothelium ↗Multiple Sclerosis Journal · 2017 · PMID 28984166not yet assessed
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Analysis of Lymphocyte Extravasation Using an <em>In Vitro</em> Model of the Human Blood-brain Barrier ↗Journal of Visualized Experiments · 2017 · PMID 28448020not yet assessed
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Nitazoxanide May Modify the Course of Progressive Multifocal Leukoencephalopathy ↗Journal of Clinical Immunology · 2017 · PMID 29159786not yet assessed
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Blockade of MCAM on T(H)17 cells impedes their CNS infiltration over the choroid plexusmediaTUM – the media and publications repository of the Technical University Munich (Technical University Munich) · 2017not yet assessed
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Analysis of Lymphocyte Extravasation Using an <em>In Vitro</em> Model of the Human Blood-brain Barrier ↗Journal of Visualized Experiments · 2017not yet assessed
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Long-term natalizumab treatment enhances the pathogenic signature of Th17 cells – potential implications for treatment cessation? (P2.408) ↗Neurology · 2017not yet assessed
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Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation ↗Proceedings of the National Academy of Sciences · 2016 · PMID 27162345not yet assessed
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CD8+ T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing ↗Nature Communications · 2016 · PMID 27040081not yet assessed
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Therapy with natalizumab is associated with high JCV seroconversion and rising JCV index values ↗Neurology Neuroimmunology & Neuroinflammation · 2016 · PMID 26848486not yet assessed
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Melanocortin-1 receptor activation is neuroprotective in mouse models of neuroinflammatory disease ↗Science Translational Medicine · 2016 · PMID 27797962not yet assessed
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Distinct pattern of lesion distribution in multiple sclerosis is associated with different circulating T-helper and helper-like innate lymphoid cell subsets ↗Multiple Sclerosis Journal · 2016 · PMID 27481205not yet assessed
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CD62L test at 2 years of natalizumab predicts progressive multifocal leukoencephalopathy ↗Neurology · 2016 · PMID 27815407not yet assessed
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B7-H1 shapes T-cell–mediated brain endothelial cell dysfunction and regional encephalitogenicity in spontaneous CNS autoimmunity ↗Proceedings of the National Academy of Sciences · 2016 · PMID 27671636not yet assessed
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CD62L is not a reliable biomarker for predicting PML risk in natalizumab-treated R-MS patients ↗Neurology · 2016 · PMID 28296380not yet assessed
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L-Selektin ist kein zuverlässiger Marker ↗InFo Neurologie + Psychiatrie · 2016not yet assessed
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Therapy with Natalizumab Is Associated with High JCV Sero-Conversion and Rising JCV Index Values (P2.064) ↗Neurology · 2016not yet assessed
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Pathogenicity of Rasmussen Encephalitis CD8+ Lymphocytes Elucidated by Large-Scale Sequencing of the T-Cell Receptor Repertoire (P5.242) ↗Neurology · 2016not yet assessed
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Prospective, multicentric study of using JCV serology and L-selectin for PML risk assessmentMultiple Sclerosis Journal · 2016not yet assessed
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Referee report. For: The TOUCH program and natalizumab: Fundamental flaw in patient protection [version 2; referees: 1 approved, 1 approved with reservations] ↗Faculty of 1000 Research Ltd · 2016not yet assessed
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Referee report. For: The TOUCH program and natalizumab: Fundamental flaw in patient protection [version 1; referees: 2 approved with reservations] ↗Faculty of 1000 Research Ltd · 2016not yet assessed
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PML risk stratification using anti-JCV antibody index and L-selectin ↗Multiple Sclerosis Journal · 2015 · PMID 26432858not yet assessed
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Assessment of immune functions and MRI disease activity in relapsing-remitting multiple sclerosis patients switching from natalizumab to fingolimod (ToFingo-Successor) ↗BMC Neurology · 2015 · PMID 26099927not yet assessed
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Trafficking of lymphocytes into the CNS ↗Oncotarget · 2015 · PMID 26255669not yet assessed
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VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells ↗The Journal of Experimental Medicine · 2014 · PMID 25135296not yet assessed
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Ultraviolet B light attenuates the systemic immune response in central nervous system autoimmunity ↗Annals of Neurology · 2014 · PMID 24771567not yet assessed
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Therapeutic uses of anti-α4-integrin (anti-VLA-4) antibodies in multiple sclerosis ↗International Immunology · 2014 · PMID 25326459not yet assessed
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Specific loss of cellular L-selectin on CD4+ T cells is associated with progressive multifocal leukoencephalopathy development during HIV infection ↗AIDS · 2014 · PMID 24445368not yet assessed
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VLA-4 blockade promotes differential routes into human CNS involving PSGL-1 rolling of T cells and MCAM-adhesion of TH17 cells ↗Journal of Neuroimmunology · 2014not yet assessed
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JCV index and L-selectin for natalizumab-associated PML risk stratification ↗Journal of Neuroimmunology · 2014not yet assessed
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The pathophysiological role of cytotoxic CD8 T cells in Susac syndrome ↗Journal of Neuroimmunology · 2014not yet assessed
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UVB light attenuates the systemic immune response in CNS autoimmunity ↗Journal of Neuroimmunology · 2014not yet assessed
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<scp>l</scp> -Selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients ↗Neurology · 2013 · PMID 23925765not yet assessed
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CD4+NKG2D+ T Cells Exhibit Enhanced Migratory and Encephalitogenic Properties in Neuroinflammation ↗PLoS ONE · 2013 · PMID 24282598not yet assessed
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Correction: CD4<sup>+</sup>NKG2D<sup>+</sup>T Cells Exhibit Enhanced Migratory and Encephalitogenic Properties in Neuroinflammation ↗PLoS ONE · 2013not yet assessed
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Fatal PML associated with efalizumab therapy ↗Neurology · 2012 · PMID 22302546not yet assessed
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CD8+ T-cell immunity in chronic inflammatory demyelinating polyradiculoneuropathy ↗Neurology · 2012 · PMID 22238416not yet assessed
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Immunological and clinical consequences of treating a patient with natalizumab ↗Multiple Sclerosis Journal · 2011 · PMID 21908480not yet assessed
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Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation ↗Blood · 2010 · PMID 20215643not yet assessed
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Regulatory T cells exhibit enhanced migratory characteristics, a feature impaired in patients with multiple sclerosis ↗European Journal of Immunology · 2010 · PMID 21108477not yet assessed
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FOXP3+ T regulatory cells in idiopathic inflammatory myopathies ↗Journal of Neuroimmunology · 2010 · PMID 20537411not yet assessed
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An Imbalance of Two Functionally and Phenotypically Different Subsets of Plasmacytoid Dendritic Cells Characterizes the Dysfunctional Immune Regulation in Multiple Sclerosis ↗The Journal of Immunology · 2010 · PMID 20357264not yet assessed
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Temporal Pattern of ICAM-I Mediated Regulatory T Cell Recruitment to Sites of Inflammation in Adoptive Transfer Model of Multiple Sclerosis ↗PLoS ONE · 2010 · PMID 21085578not yet assessed
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Janus head: the dual role of HLA-G in CNS immunity ↗Cellular and Molecular Life Sciences · 2010 · PMID 21086150not yet assessed
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CD8+ T-cell clones dominate brain infiltrates in Rasmussen encephalitis and persist in the periphery ↗Brain · 2009 · PMID 19179379not yet assessed
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T cell suppression by naturally occurring HLA-G-expressing regulatory CD4+ T cells is IL-10-dependent and reversible ↗Journal of Leukocyte Biology · 2009 · PMID 19401389not yet assessed
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Accelerated Course of Experimental Autoimmune Encephalomyelitis in PD-1-Deficient Central Nervous System Myelin Mutants ↗American Journal Of Pathology · 2009 · PMID 19443704not yet assessed
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Intercellular exchanges of membrane fragments (trogocytosis) between human muscle cells and immune cells: A potential mechanism for the modulation of muscular immune responses ↗Journal of Neuroimmunology · 2009 · PMID 19269695not yet assessed
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PD-1 Regulates Neural Damage in Oligodendroglia-Induced Inflammation ↗PLoS ONE · 2009 · PMID 19197390not yet assessed
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The co-inhibitory molecule PD-1 modulates disease severity in a model for an inherited, demyelinating neuropathy ↗Neurobiology of Disease · 2008 · PMID 18996482not yet assessed
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Human myoblasts modulate the function of antigen-presenting cells ↗Journal of Neuroimmunology · 2008 · PMID 18644633not yet assessed
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Clonal expansions of pathogenic CD8+ effector cells in the CNS of myelin mutant mice ↗Molecular and Cellular Neuroscience · 2007 · PMID 17889554not yet assessed
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Effects of somatostatin and captopril on glomerular prostaglandin E2 production in normal and diabetic rats ↗Prostaglandins · 1993 · PMID 8104353not yet assessed
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Increased renal responsiveness to human atrial natriuretic peptide in patients with active acromegaly ↗European Journal of Endocrinology · 1988not yet assessed
Full bibliography from OpenAlex; reproducibility verdicts matched by PMID.
Author attribution follows OpenAlex disambiguation, which is imperfect — a researcher's papers can be split across profiles or mixed with a namesake.
Merged across profiles sharing this ORCID where present. See every “Schwab N” paper on PubMed ↗