E. John Wherry
Reproducibility track record
1
assessed papers
88/100
mean reproducibility
1
reproduced (C1–C2)
0
flagged
53
total citations
flag rate:
0%
(0/1)
The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.
Authorship role
first author: 0
last author: 1
Topics
Funders
—
Frequent co-authors
Kenneth E. Schmader 1Andrew V. Kossenkov 1Ramin S. Herati 1Bertram Bengsch 1Cécile Alanio 1Alexander Muselman 1Hildegund C.J. Ertl 1Laura A. Vella 1Luisa Victoria Silva 1David H. Canaday 1
Institutions
New York University 1University of Pennsylvania 1Children's Hospital of Philadelphia 1Stanford University 1Translational Therapeutics (United States) 1University Medical Center Freiburg 1
Geography (author institutions)
US 1DE 1
Co-author network
Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.
How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.
Assessed papers (1)
Complete publication record (640)
Request a reproduction →1 assessed by us (1 reproduced) · 639 not yet assessed — every PubMed paper on record, linked below.
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Perturbation of the preterm human immune system in early life ↗JCI Insight · 2026 · PMID 40950464not yet assessed
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New insights into progenitor exhausted T cell populations ↗Nature reviews. Immunology · 2026 · PMID 42380632not yet assessed
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460 LYNCH SYNDROME CARRIERS HAVE SIMILAR PREVALENCE OF IBD BUT LOWER OVERALL PREVALENCE OF AUTOIMMUNE DISEASES COMPARED TO CONTROLS ↗Gastroenterology · 2026not yet assessed
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460 LYNCH SYNDROME CARRIERS HAVE SIMILAR PREVALENCE OF IBD BUT LOWER OVERALL PREVALENCE OF AUTOIMMUNE DISEASES COMPARED TO CONTROLS ↗Gastrointestinal Endoscopy · 2026not yet assessed
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The critical role of the endogenous immune compartment after CAR T cell therapy in recurrent GBM ↗Cell · 2026 · PMID 42296961not yet assessed
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Deep learning representations of human Immune Health for precision immunology ↗bioRxiv (Cold Spring Harbor Laboratory) · 2026not yet assessed
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Ready-to-load MHC-I nanoparticles for high-throughput T cell screening studies ↗Science Advances · 2026 · PMID 39763982not yet assessed
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Multimodal analysis reveals polyclonality and inflammatory programs specific to TRBV11-2+ CD4 T cells in MIS-C ↗Zenodo (CERN European Organization for Nuclear Research) · 2026not yet assessed
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Multimodal analysis reveals polyclonality and inflammatory programs specific to TRBV11-2+ CD4 T cells in MIS-C ↗Zenodo (CERN European Organization for Nuclear Research) · 2026not yet assessed
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Guidelines for T cell nomenclature ↗Nature reviews. Immunology · 2025 · PMID 41254224not yet assessed
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Targeting the SARS-CoV-2 reservoir in long COVID ↗The Lancet Infectious Diseases · 2025 · PMID 39947217not yet assessed
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Multi-omic profiling reveals age-related immune dynamics in healthy adults ↗Nature · 2025 · PMID 41162704not yet assessed
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Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate ↗Science Immunology · 2025 · PMID 40053604not yet assessed
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Anti-CTLA-4 generates greater memory response than anti-PD-1 via TCF-1 ↗Proceedings of the National Academy of Sciences · 2025 · PMID 39786926not yet assessed
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A tumor-on-a-chip for in vitro study of CAR-T cell immunotherapy in solid tumors ↗Nature Biotechnology · 2025 · PMID 41107533not yet assessed
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Deciphering the role of histone modifications in memory and exhausted CD8 T cells ↗Scientific Reports · 2025 · PMID 40389726not yet assessed
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Thrombospondin-1–CD47 signaling contributes to the development of T cell exhaustion in cancer ↗Nature Immunology · 2025 · PMID 41249483not yet assessed
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Automated cytometric gating with human-level performance using bivariate segmentation ↗Nature Communications · 2025 · PMID 39939580not yet assessed
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The transcription factor BATF pioneers the differentiation program of effector CD8+ T cells through the interaction with IRF4 ↗Cell Reports · 2025 · PMID 40773348not yet assessed
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Durable T cell immunity to COVID-19 vaccines in MS patients on B cell depletion therapy ↗npj Vaccines · 2025 · PMID 40382362not yet assessed
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Chromatin repression by PRC2 results in reduced gene expression driving key features of CD8 T cell exhaustion ↗The Journal of Immunology · 2025 · PMID 40795221not yet assessed
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Large-scale evaluation of proteomic and polygenic risk scores reveals complementary contributions to incident disease prediction ↗medRxiv · 2025 · PMID 40672481not yet assessed
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Geometric Tuning of Cytokine Receptor Association Modulates Synthetic Agonist Signaling ↗bioRxiv (Cold Spring Harbor Laboratory) · 2025 · PMID 41279521not yet assessed
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High-Throughput De Novo Protein Design Yields Novel Immunomodulatory Agonists ↗bioRxiv (Cold Spring Harbor Laboratory) · 2025 · PMID 41279583not yet assessed
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Revitalizing systemic immune responses in advanced NSCLC using FLT3L and SBRT ↗medRxiv · 2025 · PMID 39974012not yet assessed
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Divergent ontogeny of Tissue Resident Memory and Tissue Resident Exhausted CD8 <sup>+</sup> T cells underlies distinct functional potential ↗bioRxiv (Cold Spring Harbor Laboratory) · 2025 · PMID 40832341not yet assessed
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In vivo reprogramming of cytotoxic effector CD8 <sup>+</sup> T cells via fractalkine-conjugated mRNA-LNP ↗bioRxiv (Cold Spring Harbor Laboratory) · 2025 · PMID 41278637not yet assessed
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Cleanet: robust doublet detection in cytometry data based on protein expression patterns ↗bioRxiv (Cold Spring Harbor Laboratory) · 2025not yet assessed
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37: DYSREGULATED STAT3 SIGNALING DEFINES A TARGETABLE, HIGH-MORTALITY SUBPHENOTYPE OF PEDIATRIC SEPSIS ↗Critical Care Medicine · 2025not yet assessed
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Deciphering the role of histone modifications in memory and exhausted CD8 T cells ↗bioRxiv (Cold Spring Harbor Laboratory) · 2025not yet assessed
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Longitudinal evolution of tumor and immune system after intracranial CAR T cell therapy in recurrent GBM ↗Cytotherapy · 2025not yet assessed
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Defining a New Pediatric Sepsis Endotype Associated With Bystander T Cell Activation, Dysregulated STAT3 Signaling, and Poor Prognosis ↗American Journal of Respiratory and Critical Care Medicine · 2025not yet assessed
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0038 Therapeutic insights from spatial mapping of hidradenitis suppurativa skin lesions at single cell resolution ↗Journal of Investigative Dermatology · 2025not yet assessed
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245 Synthetic pathway activators (SPA) enhance CAR-T activity against solid tumors by reducing T cell exhaustion and increasing functional persistence in preclinical studies ↗Regular and Young Investigator Award Abstracts · 2025not yet assessed
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DDDR-63. Immune remodeling in CSF and tumor predicts response to CAR T therapy in glioblastoma ↗Neuro-Oncology · 2025not yet assessed
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The MMTV envelope glycoprotein promotes the survival and function of CD8 T cells during chronic viral infection and cancer via ITAM-dependent signaling 3439 ↗The Journal of Immunology · 2025not yet assessed
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Representing immune profiles with self-supervised set representation learning 4557 ↗The Journal of Immunology · 2025not yet assessed
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Divergent ontogeny of tissue resident memory and tissue resident exhausted CD8 T cells underlies distinct functional potential 4588 ↗The Journal of Immunology · 2025not yet assessed
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Online resources from the Allen institute for immunology: the human immune health atlas and human immune system explorer platform 3326 ↗The Journal of Immunology · 2025not yet assessed
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Tumor-specific stem-like progenitor exhausted CD8+ T cell subsets diverge into terminally exhausted cells and long-lived memory T cells 3102 ↗The Journal of Immunology · 2025not yet assessed
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LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity ↗Cell · 2024 · PMID 39121848not yet assessed
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Combined JAK inhibition and PD-1 immunotherapy for non–small cell lung cancer patients ↗Science · 2024 · PMID 38900877not yet assessed
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Repeated peripheral infusions of anti-EGFRvIII CAR T cells in combination with pembrolizumab show no efficacy in glioblastoma: a phase 1 trial ↗Nature Cancer · 2024 · PMID 38216766not yet assessed
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LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity ↗Cell · 2024 · PMID 39121847not yet assessed
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Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants ↗Immunity · 2024 · PMID 38490198not yet assessed
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TET2 regulates early and late transitions in exhausted CD8 <sup>+</sup> T cell differentiation and limits CAR T cell function ↗Science Advances · 2024 · PMID 39536093not yet assessed
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Nivolumab for mismatch-repair-deficient or hypermutated gynecologic cancers: a phase 2 trial with biomarker analyses ↗Nature Medicine · 2024 · PMID 38653864not yet assessed
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FDG PET/CT Imaging 1 Week after a Single Dose of Pembrolizumab Predicts Treatment Response in Patients with Advanced Melanoma ↗Clinical Cancer Research · 2024 · PMID 38263597not yet assessed
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Recovery of biological signals lost in single-cell batch integration with CellANOVA ↗Nature Biotechnology · 2024 · PMID 39592777not yet assessed
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Cytometry masked autoencoder: An accurate and interpretable automated immunophenotyper ↗Cell Reports Medicine · 2024 · PMID 39515318not yet assessed
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Neonatal CD8+ T Cells Resist Exhaustion during Chronic Infection ↗The Journal of Immunology · 2024 · PMID 38231127not yet assessed
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526 Pharmacokinetic and pharmacodynamic analyses of PD-1 blockade with nivolumab at varying doses and schedules supports administration at markedly reduced dose and frequency ↗Regular and Young Investigator Award Abstracts · 2024not yet assessed
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Longitudinal Multi-omic Immune Profiling Reveals Age-Related Immune Cell Dynamics in Healthy Adults ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024 · PMID 39314416not yet assessed
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Immunological imprinting shapes the specificity of human antibody responses against SARS-CoV-2 variants ↗medRxiv · 2024 · PMID 38260304not yet assessed
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Cytometry Masked Autoencoder: An Accurate and Interpretable Automated Immunophenotyper ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024not yet assessed
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Automated Cytometric Gating with Human-Level Performance Using Bivariate Segmentation ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024 · PMID 38766268not yet assessed
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Temporal multi-modal single-cell analyses reveal dynamic interactions of CAR-T cells with glioblastoma and targeting of antigen-negative neoplastic cells ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024not yet assessed
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Aberrant STAT signaling drives T cell dysregulation in a targetable pediatric sepsis endotype ↗medRxiv · 2024 · PMID 38946991not yet assessed
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Author Correction: Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment ↗Nature Immunology · 2024 · PMID 38267693not yet assessed
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Abstract A050: CD8+ T cell exhaustion and their DNA damage in BRCA1 mutated TNBC ↗Cancer Research · 2024not yet assessed
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Abstract 1689: CRISPR functional genetic screening for immune enhancers of inhibitor receptors in human primary CD8 T cells ↗Cancer Research · 2024not yet assessed
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TET2 regulates early and late transitions in exhausted CD8 <sup>+</sup> T-cell differentiation and limits CAR T-cell function ↗bioRxiv (Cold Spring Harbor Laboratory) · 2024not yet assessed
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The future of immunology: a Lofoten perspective ↗Immunology and Cell Biology · 2024 · PMID 38994681not yet assessed
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Fate mapping LAG3+ exhausted CD8+ T cells. ↗The Journal of Immunology · 2024not yet assessed
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CD8+ T cells in the cancer-immunity cycle ↗Immunity · 2023 · PMID 37820583not yet assessed
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Serotonin reduction in post-acute sequelae of viral infection ↗Cell · 2023 · PMID 37848036not yet assessed
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The enteric nervous system relays psychological stress to intestinal inflammation ↗Cell · 2023 · PMID 37236193not yet assessed
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SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC) ↗Nature Immunology · 2023 · PMID 37667052not yet assessed
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Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells toward durable effector-like states during chronic antigen exposure ↗Immunity · 2023 · PMID 38091951not yet assessed
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Prior vaccination promotes early activation of memory T cells and enhances immune responses during SARS-CoV-2 breakthrough infection ↗Nature Immunology · 2023 · PMID 37735592not yet assessed
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Efficient engineering of human and mouse primary cells using peptide-assisted genome editing ↗Nature Biotechnology · 2023 · PMID 37095348not yet assessed
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Cancer cells resistant to immune checkpoint blockade acquire interferon-associated epigenetic memory to sustain T cell dysfunction ↗Nature Cancer · 2023 · PMID 36646856not yet assessed
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A statistical framework for differential pseudotime analysis with multiple single-cell RNA-seq samples ↗Nature Communications · 2023 · PMID 37949861not yet assessed
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Phase I Trial of Autologous RNA-electroporated cMET-directed CAR T Cells Administered Intravenously in Patients with Melanoma and Breast Carcinoma ↗Cancer Research Communications · 2023 · PMID 37377890not yet assessed
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In vitro modeling of CD8 <sup>+</sup> T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40 ↗Science Immunology · 2023 · PMID 37595022not yet assessed
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The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells ↗Immunity · 2023 · PMID 37315535not yet assessed
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Human T follicular helper clones seed the germinal center–resident regulatory pool ↗Science Immunology · 2023 · PMID 37027481not yet assessed
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Trimodal single-cell profiling reveals a novel pediatric CD8αα+ T cell subset and broad age-related molecular reprogramming across the T cell compartment ↗Nature Immunology · 2023 · PMID 37845489not yet assessed
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SARS-CoV-2 vaccination enhances the effector qualities of spike-specific T cells induced by COVID-19 ↗Science Immunology · 2023 · PMID 38064569not yet assessed
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Deep phenotyping of the lipidomic response in COVID‐19 and non‐COVID‐19 sepsis ↗Clinical and Translational Medicine · 2023 · PMID 37948331not yet assessed
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Intrinsically disordered domain of transcription factor TCF-1 is required for T cell developmental fidelity ↗Nature Immunology · 2023 · PMID 37592014not yet assessed
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A T cell receptor β chain–directed antibody fusion molecule activates and expands subsets of T cells to promote antitumor activity ↗Science Translational Medicine · 2023 · PMID 38019931not yet assessed
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The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR+ CD8+ effector state, and its deletion improves checkpoint blockade ↗Cell Reports · 2023 · PMID 37527035not yet assessed
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High-throughput interrogation of immune responses using the Human Immune Profiling Pipeline ↗STAR Protocols · 2023 · PMID 37159385not yet assessed
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Signal recovery in single cell batch integration ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37215021not yet assessed
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Author Correction: SARS-CoV-2 reservoir in post-acute sequelae of COVID-19 (PASC) ↗Nature Immunology · 2023 · PMID 37723351not yet assessed
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Prior vaccination enhances immune responses during SARS-CoV-2 breakthrough infection with early activation of memory T cells followed by production of potent neutralizing antibodies ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 36798171not yet assessed
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PD1 inhibition and GITR agonism in combination with fractionated stereotactic radiotherapy for the treatment of recurrent glioblastoma: A phase 2, multi-arm study. ↗Journal of Clinical Oncology · 2023not yet assessed
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Deep Phenotyping of the Lipidomic Response in COVID and non-COVID Sepsis ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37398323not yet assessed
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<i>In Vitro</i> Modeling of CD8 T Cell Exhaustion Enables CRISPR Screening to Reveal a Role for BHLHE40 ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 37131713not yet assessed
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CTIM-24. REPEATED PERIPHERAL INFUSIONS OF ANTI-EGFRVIII CAR T CELLS IN COMBINATION WITH PEMBROLIZUMAB REMODELS THE TUMOR MICROENVIRONMENT IN DE NOVO GLIOBLASTOMA ↗Neuro-Oncology · 2023not yet assessed
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Booster mRNA vaccination post-SARS-CoV-2 infection enhances functional qualities of T cell immunity ↗Research Square · 2023not yet assessed
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Reinvigoration of Progenitor-Exhausted CD8 T Cells by anti-CTLA-4 Contributes to the Sustained Activity of Combination Checkpoint Blockade ↗SSRN Electronic Journal · 2023not yet assessed
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The pseudokinase Trib1 regulates the transition of exhausted T cells to a KLR <sup>+</sup> CD8 <sup>+</sup> effector state and its deletion improves checkpoint blockade ↗bioRxiv (Cold Spring Harbor Laboratory) · 2023 · PMID 36824931not yet assessed
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Abstract 4648: How inherited mutations affect single cells within the tumor microenvironment in breast tumors stratified by receptor status ↗Cancer Research · 2023not yet assessed
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Booster mRNA vaccination post-SARS-CoV-2 infection enhances functional qualities of T cell immunity ↗The Journal of Immunology · 2023not yet assessed
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Tri-modal single cell (TEA-seq) profiling reveals a novel, epigenetically distinct T cell subset in children and global molecular reprogramming across age ↗The Journal of Immunology · 2023not yet assessed
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1016 Enforcement of exhausted T cell epigenetic fate by HMG-box transcription factor TOX ↗Regular and Young Investigator Award Abstracts · 2023not yet assessed
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Decade-long leukaemia remissions with persistence of CD4+ CAR T cells ↗Nature · 2022 · PMID 35110735not yet assessed
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Sotigalimab and/or nivolumab with chemotherapy in first-line metastatic pancreatic cancer: clinical and immunologic analyses from the randomized phase 2 PRINCE trial ↗Nature Medicine · 2022 · PMID 35662283not yet assessed
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Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics ↗Nature Immunology · 2022 · PMID 36271148not yet assessed
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Divergent clonal differentiation trajectories of T cell exhaustion ↗Nature Immunology · 2022 · PMID 36289450not yet assessed
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Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine ↗Cell · 2022 · PMID 35523182not yet assessed
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T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma ↗Journal of Hepatology · 2022 · PMID 35367533not yet assessed
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Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals ↗Cell · 2022 · PMID 35202565not yet assessed
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Disentangling the relative importance of T cell responses in COVID-19: leading actors or supporting cast? ↗Nature reviews. Immunology · 2022 · PMID 35484322not yet assessed
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Understanding T cell responses to COVID-19 is essential for informing public health strategies ↗Science Immunology · 2022 · PMID 35324269not yet assessed
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Human epigenetic and transcriptional T cell differentiation atlas for identifying functional T cell-specific enhancers ↗Immunity · 2022 · PMID 35263570not yet assessed
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Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3 ↗Nature Immunology · 2022 · PMID 35618829not yet assessed
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PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine ↗Nature Immunology · 2022 · PMID 35902637not yet assessed
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Batf-mediated epigenetic control of effector CD8 <sup>+</sup> T cell differentiation ↗Science Immunology · 2022 · PMID 35179948not yet assessed
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Cytomegalovirus Latent Infection is Associated with an Increased Risk of COVID-19-Related Hospitalization ↗The Journal of Infectious Diseases · 2022 · PMID 35134186not yet assessed
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Signaling Through FcγRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19 ↗Frontiers in Immunology · 2022 · PMID 35309299not yet assessed
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SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations ↗Cell Reports · 2022 · PMID 36261003not yet assessed
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A boost with SARS-CoV-2 BNT162b2 mRNA vaccine elicits strong humoral responses independently of the interval between the first two doses ↗Cell Reports · 2022 · PMID 36244343not yet assessed
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MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection ↗Proceedings of the National Academy of Sciences · 2022 · PMID 35446623not yet assessed
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An extended SARS-CoV-2 mRNA vaccine prime-boost interval enhances B cell immunity with limited impact on T cells ↗iScience · 2022 · PMID 36594081not yet assessed
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Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation ↗Shock · 2022 · PMID 35759301not yet assessed
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Immunologic Features in <i>De Novo</i> and Recurrent Glioblastoma Are Associated with Survival Outcomes ↗Cancer Immunology Research · 2022 · PMID 35507919not yet assessed
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Validating a Proteomic Signature of Severe COVID-19 ↗Critical Care Explorations · 2022 · PMID 36479446not yet assessed
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STAR0602, a novel TCR agonist antibody, demonstrates potent antitumor activity in refractory solid tumor models through the expansion of a novel, polyclonal effector memory T cell subset ↗European Journal of Cancer · 2022not yet assessed
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T cell immunity to COVID-19 vaccines ↗Science · 2022 · PMID 35981045not yet assessed
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Efficient recall of Omicron-reactive B cell memory after a third dose of SARS-CoV-2 mRNA vaccine ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022 · PMID 35233575not yet assessed
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Enhanced STAT5a activation rewires exhausted CD8 T cells during chronic stimulation to acquire a hybrid durable effector like state ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022not yet assessed
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Human T follicular helper clones seed the germinal center-resident regulatory pool ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022not yet assessed
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Author Correction: Decade-long leukaemia remissions with persistence of CD4+ CAR T cells ↗Nature · 2022 · PMID 36477542not yet assessed
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Longitudinal single cell transcriptional and epigenetic mapping of effector, memory, and exhausted CD8 T cells reveals shared biological circuits across distinct cell fates ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022not yet assessed
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Durable Response and Improved CD8 T Cell Plasticity in Lung Cancer Patients After PD1 Blockade and JAK Inhibition ↗medRxiv · 2022not yet assessed
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Induction of a CD8 T cell intrinsic DNA damage and repair response is associated with clinical response to PD-1 blockade in uterine cancer ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022not yet assessed
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A long interval between priming and boosting SARS-CoV-2 mRNA vaccine doses enhances B cell responses with limited impact on T cell immunity ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022not yet assessed
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Distinct Heterogeneity in the Naive T cell Compartments of Children and Adults ↗bioRxiv (Cold Spring Harbor Laboratory) · 2022not yet assessed
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A Long Interval Between Priming and Boosting SARS-CoV-2 mRNA Vaccine Doses Enhances B Cell Responses With Limited Impact on T Cell Immunity ↗SSRN Electronic Journal · 2022not yet assessed
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CTIM-35. A PHASE II STUDY OF GITR AGONIST INCAGN01876 AND PD-1 INHIBITOR RETIFANLIMAB IN COMBINATION WITH STEREOTACTIC RADIOTHERAPY IN PATIENTS WITH RECURRENT GLIOBLASTOMA ↗Neuro-Oncology · 2022not yet assessed
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Abstract IA07: Impact of immunotherapy on COVID-19 immunity: Insights from checkpoint blockade in cancer ↗Cancer Immunology Research · 2022not yet assessed
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Evidence That a Pathogenic Allele in the L-Type Calcium Channel Gene Underlies a Novel X-Linked Primary Immunodeficient Channelopathy ↗SSRN Electronic Journal · 2022not yet assessed
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Multi-ethnic Investigation of Risk and Immune Determinants of COVID-19 Outcomes ↗Research Square · 2022 · PMID 35350196not yet assessed
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Abstract 3579: T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade ↗Cancer Research · 2022not yet assessed
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Building effective collaborations for the study of COVID-19 across the severity spectrum ↗Nature Immunology · 2022 · PMID 35999396not yet assessed
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mRNA vaccines induce durable immune memory to SARS-CoV-2 and variants of concern ↗Science · 2021 · PMID 34648302not yet assessed
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Distinct antibody and memory B cell responses in SARS-CoV-2 naïve and recovered individuals after mRNA vaccination ↗Science Immunology · 2021 · PMID 33858945not yet assessed
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Cellular and humoral immune responses following SARS-CoV-2 mRNA vaccination in patients with multiple sclerosis on anti-CD20 therapy ↗Nature Medicine · 2021 · PMID 34522051not yet assessed
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Rapid induction of antigen-specific CD4+ T cells is associated with coordinated humoral and cellular immunity to SARS-CoV-2 mRNA vaccination ↗Immunity · 2021 · PMID 34453880not yet assessed
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CD8+ T cells contribute to survival in patients with COVID-19 and hematologic cancer ↗Nature Medicine · 2021 · PMID 34017137not yet assessed
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New-onset IgG autoantibodies in hospitalized patients with COVID-19 ↗Nature Communications · 2021 · PMID 34521836not yet assessed
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Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection ↗Cell · 2021 · PMID 33631096not yet assessed
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Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation ↗Nature Immunology · 2021 · PMID 34312545not yet assessed
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In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer ↗Cell · 2021 · PMID 33636129not yet assessed
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Deep immune profiling of MIS-C demonstrates marked but transient immune activation compared with adult and pediatric COVID-19 ↗Science Immunology · 2021 · PMID 33653907not yet assessed
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BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells ↗Nature Immunology · 2021 · PMID 33574619not yet assessed
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Pembrolizumab for B-cell lymphomas relapsing after or refractory to CD19-directed CAR T-cell therapy ↗Blood · 2021 · PMID 34496014not yet assessed
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Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer ↗Clinical Cancer Research · 2021 · PMID 34112709not yet assessed
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Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells ↗Cell Reports · 2021 · PMID 33979613not yet assessed
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Signatures of COVID-19 Severity and Immune Response in the Respiratory Tract Microbiome ↗mBio · 2021 · PMID 34399607not yet assessed
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Inhibitory signaling sustains a distinct early memory CD8 <sup>+</sup> T cell precursor that is resistant to DNA damage ↗Science Immunology · 2021 · PMID 33452106not yet assessed
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Proteomic profiling of MIS-C patients indicates heterogeneity relating to interferon gamma dysregulation and vascular endothelial dysfunction ↗Nature Communications · 2021 · PMID 34893640not yet assessed
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Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer ↗Journal of Clinical Investigation · 2021 · PMID 34228641not yet assessed
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Erythrocytes identify complement activation in patients with COVID-19 ↗American Journal of Physiology-Lung Cellular and Molecular Physiology · 2021 · PMID 34231390not yet assessed
-
Vaccine-induced ICOS+CD38+ circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathwaysCell Reports Medicine · 2021 · PMID 34095875L1 88/100
-
NFAT-dependent and -independent exhaustion circuits program maternal CD8 T cell hypofunction in pregnancy ↗The Journal of Experimental Medicine · 2021 · PMID 34882194not yet assessed
-
The hedgehog pathway suppresses neuropathogenesis in CD4 T cell-driven inflammation ↗Brain · 2021 · PMID 33723591not yet assessed
-
Health care worker seromonitoring reveals complex relationships between common coronavirus antibodies and COVID-19 symptom duration ↗JCI Insight · 2021 · PMID 34237028not yet assessed
-
Challenging systemic barriers to promote the inclusion, recruitment, and retention of URM faculty in STEM ↗Cell Host & Microbe · 2021 · PMID 33951460not yet assessed
-
A Cre-driven allele-conditioning line to interrogate CD4+ conventional T cells ↗Immunity · 2021 · PMID 34551314not yet assessed
-
How Did We Get a COVID-19 Vaccine in Less Than 1 Year? ↗Clinical Cancer Research · 2021 · PMID 33542081not yet assessed
-
Multisystem Inflammation and Organ Dysfunction After BNT162b2 Messenger RNA Coronavirus Disease 2019 Vaccination ↗Critical Care Explorations · 2021 · PMID 34765984not yet assessed
-
Norovirus-Specific CD8+ T Cell Responses in Human Blood and Tissues ↗Cellular and Molecular Gastroenterology and Hepatology · 2021 · PMID 33444817not yet assessed
-
Immune Dysregulation in Human ITCH Deficiency Successfully Treated with Hematopoietic Cell Transplantation ↗The Journal of Allergy and Clinical Immunology In Practice · 2021 · PMID 33894394not yet assessed
-
Subsetting the subsets: Heterogeneity and developmental relationships of T cells in human tumors ↗Science Immunology · 2021 · PMID 34301801not yet assessed
-
Final Results of a Phase I “RadVax” Trial of Hypofractionated Radiation Combined With Pembrolizumab in Patients With Metastatic Solid Tumors ↗International Journal of Radiation Oncology*Biology*Physics · 2021not yet assessed
-
Selective IgA deficiency alters systemic immune response to commensal gut microbiome ↗Journal of Allergy and Clinical Immunology · 2021not yet assessed
-
IMMU-38. DEEP IMMUNOPROFILING OF HUMAN GLIOBLASTOMA (GBM) REVEALS DIFFERENCES IN THE TUMOR IMMUNE CELL INFILTRATE IN PATIENTS WITH HIGH VS. LOW PLASMA CELL-FREE DNA (CFDNA) ↗Neuro-Oncology · 2021not yet assessed
-
Memory T-Cell Heterogeneity and Terminology ↗Cold Spring Harbor Perspectives in Biology · 2021 · PMID 33782027not yet assessed
-
New-Onset IgG Autoantibodies in Hospitalized Patients with COVID-19 ↗medRxiv · 2021 · PMID 33532787not yet assessed
-
mRNA Vaccination Induces Durable Immune Memory to SARS-CoV-2 with Continued Evolution to Variants of Concern ↗bioRxiv (Cold Spring Harbor Laboratory) · 2021 · PMID 34462751not yet assessed
-
Longitudinal Analysis Reveals Distinct Antibody and Memory B Cell Responses in SARS-CoV2 Naïve and Recovered Individuals Following mRNA Vaccination ↗medRxiv · 2021 · PMID 33688691not yet assessed
-
CD8 T cells compensate for impaired humoral immunity in COVID-19 patients with hematologic cancer ↗Research Square · 2021 · PMID 33564756not yet assessed
-
not yet assessed
-
Germinal center responses to SARS-CoV-2 mRNA vaccines in healthy and immunocompromised individuals ↗medRxiv · 2021 · PMID 34580676not yet assessed
-
Rapid induction of antigen-specific CD4 <sup>+</sup> T cells guides coordinated humoral and cellular immune responses to SARS-CoV-2 mRNA vaccination ↗bioRxiv (Cold Spring Harbor Laboratory) · 2021not yet assessed
-
Author Correction: Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia ↗Nature Medicine · 2021 · PMID 33547459not yet assessed
-
Divergent clonal differentiation trajectories of T cell exhaustion ↗bioRxiv (Cold Spring Harbor Laboratory) · 2021not yet assessed
-
Signatures of COVID-19 severity and immune response in the respiratory tract microbiome ↗medRxiv · 2021 · PMID 33851179not yet assessed
-
A statistical framework for differential pseudotime analysis with multiple single-cell RNA-seq samples ↗bioRxiv (Cold Spring Harbor Laboratory) · 2021 · PMID 34282418not yet assessed
-
Signaling through FcγRIIA and the C5a-C5aR pathway mediates platelet hyperactivation in COVID-19 ↗bioRxiv (Cold Spring Harbor Laboratory) · 2021 · PMID 33972943not yet assessed
-
Sero-monitoring of health care workers reveals complex relationships between common coronavirus antibodies and SARS-CoV-2 severity ↗medRxiv · 2021 · PMID 33907765not yet assessed
-
Author Correction: Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation ↗Nature Immunology · 2021 · PMID 34588688not yet assessed
-
SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared to SARS-CoV-2 mRNA vaccinations ↗medRxiv · 2021not yet assessed
-
Proteomic Profiling of MIS-C Patients Reveals Heterogeneity Relating to Interferon Gamma Dysregulation and Vascular Endothelial Dysfunction ↗medRxiv · 2021 · PMID 33907759not yet assessed
-
Final results of a phase I “RadVax” trial of hypofractionated radiation combined with pembrolizumab in patients with metastatic solid tumors. ↗Journal of Clinical Oncology · 2021not yet assessed
-
Batf-mediated Epigenetic Control of Effector CD8+ T Cell Differentiation ↗bioRxiv (Cold Spring Harbor Laboratory) · 2021not yet assessed
-
Decade-Long Remissions of Leukemia Sustained By the Persistence of Activated CD4+ CAR T-Cells ↗Blood · 2021not yet assessed
-
Author Correction: BACH2 enforces the transcriptional and epigenetic programs of stem-like CD8+ T cells ↗Nature Immunology · 2021 · PMID 33658708not yet assessed
-
Decade-long remissions of leukemia sustained by the persistence of activated CD4 <sup>+</sup> CAR T-cells ↗bioRxiv (Cold Spring Harbor Laboratory) · 2021not yet assessed
-
TET2 controls differentiation of terminally exhausted CD8 T cells ↗The Journal of Immunology · 2021not yet assessed
-
Decade-long remissions of leukemia sustained by the persistence of activated CD4+ CAR T-cells ↗Research Square · 2021not yet assessed
-
Abstract 2723: How BRCA1/2 mutations in TNBC affect TME and subsequently immune cell functions ↗Cancer Research · 2021not yet assessed
-
not yet assessed
-
Abstract PO068: Distinct immune signatures predicting clinical response to PD-1 blockade therapy in gynecological cancers revealed by high-dimensional immune profiling ↗Cancer Immunology Research · 2021not yet assessed
-
Preferential Loss of Peripheral Non-Naïve CD4+ Lymphocytes in Pediatric Sepsis ↗Journal of Allergy and Clinical Immunology · 2021not yet assessed
-
not yet assessed
-
Immunological features of de novo and recurrent glioblastoma associate with survival in glioblastoma ↗Cytotherapy · 2021not yet assessed
-
Plasma Resistin Levels Are Associated with Acute Kidney Injury in Hospitalized COVID-19 Patients ↗2021not yet assessed
-
Abstract CT005: T cell inflammation in the tumor microenvironment after agonist CD40 antibody: Clinical and translational results of a neoadjuvant clinical trial ↗Cancer Research · 2021not yet assessed
-
mRNA COVID-19 vaccine efficacy in recovered vs COVID-naive individuals ↗The biomedical & life sciences collection. · 2021not yet assessed
-
not yet assessed
-
253 PD1 and LAG3 converge to limit polyfunctionality and systemic immunity ↗Regular and Young Investigator Award Abstracts · 2021not yet assessed
-
310 T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade ↗Regular and Young Investigator Award Abstracts · 2021not yet assessed
-
A role for the transcription factor STAT5 in antagonizing CD8+ T cell exhaustion ↗The Journal of Immunology · 2021not yet assessed
-
Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications ↗Science · 2020 · PMID 32669297not yet assessed
-
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms ↗Immunity · 2020 · PMID 32396847not yet assessed
-
T cell responses in patients with COVID-19 ↗Nature reviews. Immunology · 2020 · PMID 32728222not yet assessed
-
Comprehensive mapping of immune perturbations associated with severe COVID-19 ↗Science Immunology · 2020 · PMID 32669287not yet assessed
-
CD40 agonistic monoclonal antibody APX005M (sotigalimab) and chemotherapy, with or without nivolumab, for the treatment of metastatic pancreatic adenocarcinoma: an open-label, multicentre, phase 1b study ↗The Lancet Oncology · 2020 · PMID 33387490not yet assessed
-
The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans ↗Immunity · 2020 · PMID 32353250not yet assessed
-
Priority COVID-19 Vaccination for Patients with Cancer while Vaccine Supply Is Limited ↗Cancer Discovery · 2020 · PMID 33355178not yet assessed
-
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity ↗Nature Immunology · 2020 · PMID 32661362not yet assessed
-
SARS-CoV-2 seroprevalence among parturient women in Philadelphia ↗Science Immunology · 2020 · PMID 32727884not yet assessed
-
The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection ↗Cell Reports · 2020 · PMID 32610128not yet assessed
-
The Identity of Human Tissue-Emigrant CD8+ T Cells ↗Cell · 2020 · PMID 33306960not yet assessed
-
Unique challenges for glioblastoma immunotherapy—discussions across neuro-oncology and non-neuro-oncology experts in cancer immunology. Meeting Report from the 2019 SNO Immuno-Oncology Think Tank ↗Neuro-Oncology · 2020 · PMID 33367885not yet assessed
-
PPT1 inhibition enhances the antitumor activity of anti–PD-1 antibody in melanoma ↗JCI Insight · 2020 · PMID 32780726not yet assessed
-
Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2) Antibody Responses in Children With Multisystem Inflammatory Syndrome in Children (MIS-C) and Mild and Severe Coronavirus Disease 2019 (COVID-19) ↗Journal of the Pediatric Infectious Diseases Society · 2020 · PMID 33263756not yet assessed
-
Trib1 regulates T cell differentiation during chronic infection by restraining the effector program ↗The Journal of Experimental Medicine · 2020 · PMID 32150623not yet assessed
-
Reinvigorating NIH Grant Peer Review ↗Immunity · 2020 · PMID 31940266not yet assessed
-
Mice Lacking the Purinergic Receptor P2X5 Exhibit Defective Inflammasome Activation and Early Susceptibility to <i>Listeria monocytogenes</i> ↗The Journal of Immunology · 2020 · PMID 32540996not yet assessed
-
Combining Radiation with Immunotherapy: The University of Pennsylvania Experience ↗Seminars in Radiation Oncology · 2020 · PMID 32381296not yet assessed
-
Exploration of T-Cell Diversity Using Mass Cytometry ↗Methods in molecular biology · 2020 · PMID 31933194not yet assessed
-
Immune Stimulation With Recombinant Human Granulocyte Colony–Stimulating Factor for Coronavirus Disease 2019 (COVID-19)—Beware of Blind Spots ↗JAMA Internal Medicine · 2020 · PMID 32910155not yet assessed
-
Deep immune profiling of COVID-19 patients reveals patient heterogeneity and distinct immunotypes with implications for therapeutic interventions ↗bioRxiv (Cold Spring Harbor Laboratory) · 2020 · PMID 32511371not yet assessed
-
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection ↗medRxiv · 2020 · PMID 33200143not yet assessed
-
Immunologic perturbations in severe COVID-19/SARS-CoV-2 infection ↗bioRxiv (Cold Spring Harbor Laboratory) · 2020 · PMID 32511394not yet assessed
-
Deep Immune Profiling of MIS-C demonstrates marked but transient immune activation compared to adult and pediatric COVID-19 ↗medRxiv · 2020 · PMID 32995826not yet assessed
-
Erythrocytes Reveal Complement Activation in Patients with COVID-19 ↗medRxiv · 2020 · PMID 32511554not yet assessed
-
SARS-CoV-2 antibody responses in children with MIS-C and mild and severe COVID-19 ↗medRxiv · 2020 · PMID 32839782not yet assessed
-
Phase I trial of autologous cMET-directed CAR-t cells administered intravenously in patients with melanoma & breast carcinoma. ↗Journal of Clinical Oncology · 2020not yet assessed
-
SARS-CoV-2 Seroprevalence Among Parturient Women ↗medRxiv · 2020 · PMID 32676623not yet assessed
-
SARS-CoV-2 Seroprevalence Among Parturient Women ↗Research Square (Research Square) · 2020not yet assessed
-
The identity of human tissue-emigrant CD8 <sup>+</sup> T cells ↗bioRxiv (Cold Spring Harbor Laboratory) · 2020not yet assessed
-
<i>In vivo</i> CRISPR screening identifies Fli1 as a transcriptional safeguard that restrains effector CD8 T cell differentiation during infection and cancer ↗bioRxiv (Cold Spring Harbor Laboratory) · 2020not yet assessed
-
Developmental relationships of four exhausted CD8 T cell subsets reveals underlying transcriptional and epigenetic control mechanisms ↗The Journal of Immunology · 2020not yet assessed
-
Abstract IA17: Molecular mechanisms of T-cell exhaustion and implications for immunotherapy ↗Cancer Immunology Research · 2020not yet assessed
-
Targeting TNFR2 to overcome acquired adaptive resistance to immune checkpoint blockade ↗The Journal of Immunology · 2020not yet assessed
-
Mechanisms by which Obesity Dysregulates Immunometabolic State in Asthma ↗Journal of Allergy and Clinical Immunology · 2020not yet assessed
-
IgA deficiency Alters Systemic Immune Response to Commensal Gut Microbes ↗Journal of Allergy and Clinical Immunology · 2020not yet assessed
-
Abstract B80: High dimensional DNA damage and repair (DDR) cytometric profiling of human T cell subsets revealed distinct DDR signatures ↗Cancer Immunology Research · 2020not yet assessed
-
Abstract LB-356: Deep immune profiling of de novo and recurrent glioblastoma ↗Cancer Research · 2020not yet assessed
-
Abstract IA04: Overcoming immune resistance with rationally designed combination immunotherapy ↗Cancer Research · 2020not yet assessed
-
<i>In vivo</i>&nbsp;CRISPR Screening Identifies Fli1 as a Transcriptional Safeguard that Restrains Effector CD8 T Cell Differentiation During Infection and Cancer ↗SSRN Electronic Journal · 2020not yet assessed
-
T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade ↗The Journal of Immunology · 2020not yet assessed
-
PD1 and LAG3 converge to limit polyfunctionality and systemic immunity ↗The Journal of Immunology · 2020not yet assessed
-
CD8 T Cell Exhaustion During Chronic Viral Infection and Cancer ↗Annual Review of Immunology · 2019 · PMID 30676822not yet assessed
-
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion ↗Nature · 2019 · PMID 31207603not yet assessed
-
Defining ‘T cell exhaustion’ ↗Nature reviews. Immunology · 2019 · PMID 31570879not yet assessed
-
TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision ↗Immunity · 2019 · PMID 31606264not yet assessed
-
A single dose of neoadjuvant PD-1 blockade predicts clinical outcomes in resectable melanoma ↗Nature Medicine · 2019 · PMID 30804515not yet assessed
-
Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection ↗Nature Immunology · 2019 · PMID 31209400not yet assessed
-
Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade ↗Cell · 2019 · PMID 31398344not yet assessed
-
The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs ↗Science Translational Medicine · 2019 · PMID 31189717not yet assessed
-
T follicular helper cells in human efferent lymph retain lymphoid characteristics ↗Journal of Clinical Investigation · 2019 · PMID 31264971not yet assessed
-
The long noncoding RNA <i>Morrbid</i> regulates CD8 T cells in response to viral infection ↗Proceedings of the National Academy of Sciences · 2019 · PMID 31138702not yet assessed
-
Hidden Caveat of Inducible Cre Recombinase ↗Immunity · 2019 · PMID 31618646not yet assessed
-
Common variable immunodeficiency–associated endotoxemia promotes early commitment to the T follicular lineage ↗Journal of Allergy and Clinical Immunology · 2019 · PMID 31445098not yet assessed
-
Universal Principled Review: A Community-Driven Method to Improve Peer Review ↗Cell · 2019 · PMID 31835023not yet assessed
-
Chronic viral infection promotes early germinal center exit of B cells and impaired antibody development ↗bioRxiv (Cold Spring Harbor Laboratory) · 2019not yet assessed
-
Vaccine-induced ICOS+CD38+ cTfh are sensitive biosensors of age-related changes in inflammatory pathways ↗bioRxiv (Cold Spring Harbor Laboratory) · 2019not yet assessed
-
Abstract A123: Skewed CD4 and CD8 T-cell differentiation in pancreatic cancer patients ↗Cancer Immunology Research · 2019not yet assessed
-
Abstract B012: Characterizing tumor-induced exhaustion in melanoma patients treated with neoadjuvant pembrolizumab ↗Cancer Immunology Research · 2019not yet assessed
-
Abstract A197: The HMG transcription factor TOX induces a transcriptional and epigenetic program of CD8+ T-cell exhaustion in chronic infection and cancer ↗Cancer Immunology Research · 2019not yet assessed
-
OBESITY DYSREGULATES IMMUNOMETABOLIC STATUS IN ASTHMA AND IMPACTS VACCINE RESPONSES ↗Journal of Allergy and Clinical Immunology · 2019not yet assessed
-
Abstract A166: Reprogramming of exhausted T-cells following cure of chronic viral infection ↗Cancer Immunology Research · 2019not yet assessed
-
P2.04-02 Effect of Chemotherapy, Chemoimmunotherapy, and Immunotherapy on Parameters of T Cell Exhaustion in Metastatic Non-Small Cell Lung Cancer ↗Journal of Thoracic Oncology · 2019not yet assessed
-
Mutation of an L-Type Calcium Channel Gene Leads to a Novel Human Primary Cellular Immunodeficiency ↗bioRxiv (Cold Spring Harbor Laboratory) · 2019not yet assessed
-
Expression of a core gene module of anergy governs maternal CD8+ T cell hypofunction after pregnancy ↗The Journal of Immunology · 2019not yet assessed
-
Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response ↗Nature · 2018 · PMID 30089911not yet assessed
-
Determinants of response and resistance to CD19 chimeric antigen receptor (CAR) T cell therapy of chronic lymphocytic leukemia ↗Nature Medicine · 2018 · PMID 29713085not yet assessed
-
Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy ↗Immunity · 2018 · PMID 29958801not yet assessed
-
Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells ↗Immunity · 2018 · PMID 29768164not yet assessed
-
Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells ↗Immunity · 2018 · PMID 29466756not yet assessed
-
Identification and characterization of HIV-specific resident memory CD8 <sup>+</sup> T cells in human lymphoid tissue ↗Science Immunology · 2018 · PMID 29858286not yet assessed
-
Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity ↗Cancer Cell · 2018 · PMID 29894689not yet assessed
-
Spatial distribution and function of T follicular regulatory cells in human lymph nodes ↗The Journal of Experimental Medicine · 2018 · PMID 29769249not yet assessed
-
Non-conventional Inhibitory CD4+Foxp3–PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity ↗Cancer Cell · 2018 · PMID 30300585not yet assessed
-
Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma ↗OncoImmunology · 2018 · PMID 30288340not yet assessed
-
A phase I trial of pembrolizumab with hypofractionated radiotherapy in patients with metastatic solid tumours ↗British Journal of Cancer · 2018 · PMID 30318516not yet assessed
-
Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155 ↗Cell Reports · 2018 · PMID 29768211not yet assessed
-
Limited immune surveillance in lymphoid tissue by cytolytic CD4+ T cells during health and HIV disease ↗PLoS Pathogens · 2018 · PMID 29652923not yet assessed
-
CD8 T Cell Memory Increases Immunopathology in the Perforin-Deficient Model of Hemophagocytic Lymphohistiocytosis Secondary to TNF-α ↗ImmunoHorizons · 2018 · PMID 29795796not yet assessed
-
Genomic Circuitry Underlying Immunological Response to Pediatric Acute Respiratory Infection ↗Cell Reports · 2018 · PMID 29320737not yet assessed
-
A Phase I Trial of Pembrolizumab with Hypofractionated Radiation Therapy (HFRT) in Patients with Metastatic Cancers ↗International Journal of Radiation Oncology*Biology*Physics · 2018not yet assessed
-
T-Bet Enables Tissue-Restricted B Cell Memory and Influenza Hemagglutinin Stalk-Specific Antibodies ↗SSRN Electronic Journal · 2018not yet assessed
-
Chronic Allergen Stimulation Yields T cell Dysfunction in Obese Asthmatics ↗Journal of Allergy and Clinical Immunology · 2018not yet assessed
-
A31 REPROGRAMMING OF EXHAUSTED T CELLS FOLLOWING CURE OF CHRONIC VIRAL INFECTION ↗Journal of the Canadian Association of Gastroenterology · 2018not yet assessed
-
Modulation of TFH-like cells and anti-tumor activity of immune checkpoint blockade. ↗The Journal of Immunology · 2018not yet assessed
-
The transcription factor T-bet is regulated by microRNA-155 in murine anti-viral CD8+ T cells via SHIP-1. ↗The Journal of Immunology · 2018not yet assessed
-
T-cell invigoration to tumour burden ratio associated with anti-PD-1 response ↗Nature · 2017 · PMID 28397821not yet assessed
-
Successive annual influenza vaccination induces a recurrent oligoclonotypic memory response in circulating T follicular helper cells ↗Science Immunology · 2017 · PMID 28620653not yet assessed
-
The Loss of TET2 Promotes CD8+ T Cell Memory Differentiation ↗The Journal of Immunology · 2017 · PMID 29150566not yet assessed
-
Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns ↗Journal of Immunological Methods · 2017 · PMID 28322863not yet assessed
-
Optimized retroviral transduction of mouse T cells for in vivo assessment of gene function ↗Nature Protocols · 2017 · PMID 28858287not yet assessed
-
miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb ↗Cell Reports · 2017 · PMID 28903040not yet assessed
-
Group 1 Innate Lymphoid Cell Lineage Identity Is Determined by a cis-Regulatory Element Marked by a Long Non-coding RNA ↗Immunity · 2017 · PMID 28930659not yet assessed
-
Differentiation and Protective Capacity of Virus-Specific CD8+ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche ↗Immunity · 2017 · PMID 29031786not yet assessed
-
CD4+ T Cell Differentiation in Chronic Viral Infections: The Tfh Perspective ↗Trends in Molecular Medicine · 2017 · PMID 29137933not yet assessed
-
Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory ↗PLoS Pathogens · 2017 · PMID 28827827not yet assessed
-
The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8+ T Cells via SHIP-1 ↗Frontiers in Immunology · 2017 · PMID 29358931not yet assessed
-
not yet assessed
-
Differentiation and Protective Capacity of Virus-Specific CD8The Medicine Forum · 2017not yet assessed
-
What Is the Predictive Value of Animal Models for Vaccine Efficacy in Humans? ↗Cold Spring Harbor Perspectives in Biology · 2017 · PMID 28348037not yet assessed
-
Metabolic and Deep Immune Profiling Reveal Coordinate Effects on Immune Function in Asthma and Obesity ↗Journal of Allergy and Clinical Immunology · 2017not yet assessed
-
Human Norovirus-Specific T Cell Responses ↗Gastroenterology · 2017not yet assessed
-
Correction: Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity ↗PLoS Pathogens · 2017not yet assessed
-
Modulation of the subcellular localization of T-bet and Eomes alters CD8 exhaustion during chronic LCMV infection ↗The Journal of Immunology · 2017not yet assessed
-
TET2 deficiency promotes CD8+ T cell memory differentiation ↗The Journal of Immunology · 2017not yet assessed
-
Reprogramming of exhausted T cells following elimination of chronic antigen exposure ↗The Journal of Immunology · 2017not yet assessed
-
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade ↗Science · 2016 · PMID 27789795not yet assessed
-
Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade ↗Cell · 2016 · PMID 27912061not yet assessed
-
The epigenetic landscape of T cell exhaustion ↗Science · 2016 · PMID 27789799not yet assessed
-
Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion ↗Immunity · 2016 · PMID 27496729not yet assessed
-
The long non-coding RNA Morrbid regulates Bim and short-lived myeloid cell lifespan ↗Nature · 2016 · PMID 27525555not yet assessed
-
Combination Cancer Therapies with Immune Checkpoint Blockade: Convergence on Interferon Signaling ↗Cell · 2016 · PMID 27058661not yet assessed
-
Costimulatory and Coinhibitory Receptor Pathways in Infectious Disease ↗Immunity · 2016 · PMID 27192569not yet assessed
-
Janus kinase inhibition lessens inflammation and ameliorates disease in murine models of hemophagocytic lymphohistiocytosis ↗Blood · 2016 · PMID 26825707not yet assessed
-
Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells ↗The Journal of Immunology · 2016 · PMID 27430719not yet assessed
-
Cutting Edge: B Cell–Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection ↗The Journal of Immunology · 2016 · PMID 27430722not yet assessed
-
Type I Interferon Receptor Deficiency in Dendritic Cells Facilitates Systemic Murine Norovirus Persistence Despite Enhanced Adaptive Immunity ↗PLoS Pathogens · 2016 · PMID 27327515not yet assessed
-
Antigen exposure shapes the ratio between antigen-specific Tregs and conventional T cells in human peripheral blood ↗Proceedings of the National Academy of Sciences · 2016 · PMID 27681619not yet assessed
-
Pregnancy promotes tolerance to future offspring by programming selective dysfunction in long-lived maternal T cells ↗Journal of Leukocyte Biology · 2016 · PMID 27810945not yet assessed
-
De-Risking Immunotherapy: Report of a Consensus Workshop of the Cancer Immunotherapy Consortium of the Cancer Research Institute ↗Cancer Immunology Research · 2016 · PMID 27036972not yet assessed
-
HIV Skews the Lineage-Defining Transcriptional Profile of <i>Mycobacterium tuberculosis</i>–Specific CD4+ T Cells ↗The Journal of Immunology · 2016 · PMID 26927799not yet assessed
-
Adaptive Immunity ↗Elsevier eBooks · 2016not yet assessed
-
not yet assessed
-
Abstract A056: Mechanisms of tumor response and resistance to radiation and dual checkpoint blockade in mice and patients ↗Cancer Immunology Research · 2016not yet assessed
-
Identification of flu-specific ICOS+CD38+ cTfh after influenza vaccination ↗The Journal of Immunology · 2016not yet assessed
-
Abstract IA06: Molecular basis of T cell exhaustion: Insights for immunotherapy ↗Cancer Immunology Research · 2016not yet assessed
-
Aberrant Immunity ↗Elsevier eBooks · 2016not yet assessed
-
Abstract B104: Impact of PD-1 blockade on epigenetic and transcriptional reprogramming of exhausted T cells ↗Cancer Immunology Research · 2016not yet assessed
-
MiR-150 negatively regulates CD8+ T cell memory formation ↗The Journal of Immunology · 2016not yet assessed
-
Early onset and persistence of metabolic alterations in exhausted T cells is regulated by PD-1 ↗The Journal of Immunology · 2016not yet assessed
-
ICOS+CD38+ cTfh in peripheral blood and thoracic duct lymph. ↗The Journal of Immunology · 2016not yet assessed
-
Regulation of effective vs. ineffective B cell responses to chronic viral infections. ↗The Journal of Immunology · 2016not yet assessed
-
Molecular and cellular insights into T cell exhaustion ↗Nature reviews. Immunology · 2015 · PMID 26205583not yet assessed
-
Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer ↗Nature · 2015 · PMID 25754329not yet assessed
-
Overcoming T cell exhaustion in infection and cancer ↗Trends in Immunology · 2015 · PMID 25797516not yet assessed
-
Induction of T-cell Immunity Overcomes Complete Resistance to PD-1 and CTLA-4 Blockade and Improves Survival in Pancreatic Carcinoma ↗Cancer Immunology Research · 2015 · PMID 25678581not yet assessed
-
Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+ T cells ↗The Journal of Experimental Medicine · 2015 · PMID 26034050not yet assessed
-
CD39 Expression Identifies Terminally Exhausted CD8+ T Cells ↗PLoS Pathogens · 2015 · PMID 26485519not yet assessed
-
T cell exhaustion during persistent viral infections ↗Virology · 2015 · PMID 25620767not yet assessed
-
SnapShot: T Cell Exhaustion ↗Cell · 2015 · PMID 26544946not yet assessed
-
Awakening the immune system with radiation: Optimal dose and fractionation ↗Cancer Letters · 2015 · PMID 25799953not yet assessed
-
ST2 contributes to T-cell hyperactivation and fatal hemophagocytic lymphohistiocytosis in mice ↗Blood · 2015 · PMID 26518437not yet assessed
-
Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection ↗Science · 2015 · PMID 25593185not yet assessed
-
Survival of Effector CD8+ T Cells during Influenza Infection Is Dependent on Autophagy ↗The Journal of Immunology · 2015 · PMID 25833396not yet assessed
-
Immune Memory and Exhaustion: Clinically Relevant Lessons from the LCMV Model ↗Advances in experimental medicine and biology · 2015 · PMID 26324351not yet assessed
-
Lymphocytic Choriomeningitis Virus Expands a Population of NKG2D+CD8+ T Cells That Exacerbates Disease in Mice Coinfected with <i>Leishmania major</i> ↗The Journal of Immunology · 2015 · PMID 26290604not yet assessed
-
Elevated Expression of CD160 and 2B4 Defines a Cytolytic HIV-Specific CD8<sup>+</sup>T-Cell Population in Elite Controllers ↗The Journal of Infectious Diseases · 2015 · PMID 25883386not yet assessed
-
The Orphan Nuclear Receptor TLX Is an Enhancer of STAT1-Mediated Transcription and Immunity to Toxoplasma gondii ↗PLoS Biology · 2015 · PMID 26196739not yet assessed
-
The Importance of Cooperation: Partnerless NFAT Induces T Cell Exhaustion ↗Immunity · 2015 · PMID 25692694not yet assessed
-
Acetyl CoA Carboxylase 2 Is Dispensable for CD8+ T Cell Responses ↗PLoS ONE · 2015 · PMID 26367121not yet assessed
-
Abstract CT137: Combination of agonistic CD40 monoclonal antibody CP-870,893 and anti-CTLA-4 antibody tremelimumab in patients with metastatic melanoma ↗Cancer Research · 2015not yet assessed
-
Interleukin-33 is a mediator of murine familial hemophagocytic lymphohistiocytosis (IRC5P.629) ↗The Journal of Immunology · 2015not yet assessed
-
Abstract 2858: Radiation and dual immune checkpoint blockade overcome tumor resistance and distinctly improve immunity ↗Cancer Research · 2015not yet assessed
-
CD39 expressed by CD8<sup>+</sup> T cells in HCV infection is enzymatically active. ↗Figshare · 2015not yet assessed
-
CD39 is highly up-regulated by exhausted CD8<sup>+</sup> T cells in a mouse model of chronic infection. ↗Figshare · 2015not yet assessed
-
Terminally exhausted CD8<sup>+</sup> T cells marked by high levels of CD39 are most impaired in their effector function. ↗Figshare · 2015not yet assessed
-
CD39 expression correlates with PD-1 expression and viral load in chronic viral infection. ↗Figshare · 2015not yet assessed
-
Abstract A52: Radiation and dual PD-L1 and CTLA4 checkpoint blockade non-redundantly improves tumor resistance, response, and immunity ↗Cancer Immunology Research · 2015not yet assessed
-
Response, Resistance Mechanisms, and Biomarkers for Radiation and Immune Checkpoint Blockade ↗International Journal of Radiation Oncology*Biology*Physics · 2015not yet assessed
-
CTLA-4-mediated suppressor effect by human T follicular regulatory cells (IRC11P.432) ↗The Journal of Immunology · 2015not yet assessed
-
Abstract IA01: Molecular basis of T cell exhaustion: Insights for immunotherapy ↗Cancer Immunology Research · 2015not yet assessed
-
LCMV-specific CD4 T cells induce immunopathology and impair immune protection following chronic LCMV infection (VIR1P.1132) ↗The Journal of Immunology · 2015not yet assessed
-
not yet assessed
-
Abstract A38: Phase I study of combination immunotherapy with agonistic CD40 monoclonal antibody (mAb) CP-870,893 (αCD40) and anti-CTLA-4 antibody tremelimumab (treme) in patients with metastatic melanoma ↗Cancer Immunology Research · 2015not yet assessed
-
Molecular regulation of effector and memory T cell differentiation ↗Nature Immunology · 2014 · PMID 25396352not yet assessed
-
Molecular and Transcriptional Basis of CD4+ T Cell Dysfunction during Chronic Infection ↗Immunity · 2014 · PMID 24530057not yet assessed
-
Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor–Transduced Human T cells in Solid Tumors ↗Clinical Cancer Research · 2014 · PMID 24919573not yet assessed
-
The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells ↗Nature Immunology · 2014 · PMID 24584090not yet assessed
-
Virus-helminth coinfection reveals a microbiota-independent mechanism of immunomodulation ↗Science · 2014 · PMID 25082704not yet assessed
-
Regulator of Fatty Acid Metabolism, Acetyl Coenzyme A Carboxylase 1, Controls T Cell Immunity ↗The Journal of Immunology · 2014 · PMID 24567531not yet assessed
-
Circulating CXCR5+PD-1+ Response Predicts Influenza Vaccine Antibody Responses in Young Adults but not Elderly Adults ↗The Journal of Immunology · 2014 · PMID 25172499not yet assessed
-
B Cell Antigen Presentation in the Initiation of Follicular Helper T Cell and Germinal Center Differentiation ↗The Journal of Immunology · 2014 · PMID 24646739not yet assessed
-
TIGIT and CD226: Tipping the Balance between Costimulatory and Coinhibitory Molecules to Augment the Cancer Immunotherapy Toolkit ↗Cancer Cell · 2014 · PMID 25490444not yet assessed
-
Engagement of NKG2D on Bystander Memory CD8 T Cells Promotes Increased Immunopathology following Leishmania major Infection ↗PLoS Pathogens · 2014 · PMID 24586170not yet assessed
-
Dysfunctional HIV-Specific CD8+ T Cell Proliferation Is Associated with Increased Caspase-8 Activity and Mediated by Necroptosis ↗Immunity · 2014 · PMID 25526311not yet assessed
-
Differential Induction of TLR3-Dependent Innate Immune Signaling by Closely Related Parasite Species ↗PLoS ONE · 2014 · PMID 24505488not yet assessed
-
Cutting Edge: CXCR4 Is Critical for CD8+ Memory T Cell Homeostatic Self-Renewal but Not Rechallenge Self-Renewal ↗The Journal of Immunology · 2014 · PMID 24973450not yet assessed
-
Genetic manipulation of the ApoF/Stat2 locus supports an important role for type I interferon signaling in atherosclerosis ↗Atherosclerosis · 2014 · PMID 24529150not yet assessed
-
Immunosurveillance by Antiangiogenesis: Tumor Growth Arrest by T Cell–Derived Thrombospondin-1 ↗Cancer Research · 2014 · PMID 24590059not yet assessed
-
The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8[superscript +] T cellsDSpace@MIT (Massachusetts Institute of Technology) · 2014not yet assessed
-
New Hope in the Search for Ebola Virus Treatments2014not yet assessed
-
Pregnancy Primes Graft-Destructive T Cell Memory. ↗Transplantation · 2014not yet assessed
-
Immune Responses to Persistent Viruses ↗ASM Press eBooks · 2014not yet assessed
-
Innate lymphoid cells regulate CD4+ T-cell responses to intestinal commensal bacteria ↗Nature · 2013 · PMID 23698371not yet assessed
-
Lung niches for the generation and maintenance of tissue-resident memory T cells ↗Mucosal Immunology · 2013 · PMID 24064670not yet assessed
-
The microRNA miR-155 controls CD8+ T cell responses by regulating interferon signaling ↗Nature Immunology · 2013 · PMID 23603793not yet assessed
-
Cooperativity Between CD8+ T Cells, Non-Neutralizing Antibodies, and Alveolar Macrophages Is Important for Heterosubtypic Influenza Virus Immunity ↗PLoS Pathogens · 2013 · PMID 23516357not yet assessed
-
Differential Localization of T-bet and Eomes in CD8 T Cell Memory Populations ↗The Journal of Immunology · 2013 · PMID 23455505not yet assessed
-
IL-25 simultaneously elicits distinct populations of innate lymphoid cells and multipotent progenitor type 2 (MPPtype2) cells ↗The Journal of Experimental Medicine · 2013 · PMID 23960191not yet assessed
-
Increased T-bet is associated with senescence of influenza virus-specific CD8 T cells in aged humans ↗Journal of Leukocyte Biology · 2013 · PMID 23440501not yet assessed
-
Liver Environment and HCV Replication Affect Human T-Cell Phenotype and Expression of Inhibitory Receptors ↗Gastroenterology · 2013 · PMID 24148617not yet assessed
-
Persistent Enteric Murine Norovirus Infection Is Associated with Functionally Suboptimal Virus-Specific CD8 T Cell Responses ↗Journal of Virology · 2013 · PMID 23596300not yet assessed
-
Viral Antigen Induces Differentiation of Foxp3+ Natural Regulatory T Cells in Influenza Virus–Infected Mice ↗The Journal of Immunology · 2013 · PMID 23667113not yet assessed
-
AAV8 Induces Tolerance in Murine Muscle as a Result of Poor APC Transduction, T Cell Exhaustion, and Minimal MHCI Upregulation on Target Cells ↗Molecular Therapy · 2013 · PMID 23778424not yet assessed
-
Vaccine-Induced Boosting of Influenza Virus-Specific CD4 T Cells in Younger and Aged Humans ↗PLoS ONE · 2013 · PMID 24155927not yet assessed
-
Enhanced T Cell Function in a Mouse Model of Human Glycosylation ↗The Journal of Immunology · 2013 · PMID 23709682not yet assessed
-
CD8<sup>+</sup>T Cell Exhaustion During Persistent Viral Infection is Regulated Independently of the Virus-Specific T Cell Receptor ↗Immunological Investigations · 2013 · PMID 23461613not yet assessed
-
Influenza Virus Specific CD8<sup>+</sup>T Cells Exacerbate Infection Following High Dose Influenza Challenge of Aged Mice ↗BioMed Research International · 2013 · PMID 24187666not yet assessed
-
Molecular Basis of T-Cell Exhaustion ↗Blood · 2013not yet assessed
-
Deconstructing development ↗Nature Immunology · 2013 · PMID 23685815not yet assessed
-
not yet assessed
-
An Interferon Paradox ↗Science · 2013 · PMID 23580520not yet assessed
-
Innate lymphoid cells promote airway epithelial repair through the amphiregulin-EGFR pathway (P3250) ↗The Journal of Immunology · 2013not yet assessed
-
Persistent enteric murine norovirus infection is associated with functionally suboptimal virus-specific CD8 T cell responses (P3187) ↗The Journal of Immunology · 2013not yet assessed
-
Viral antigen induces differentiation of Foxp3+ natural regulatory T cells in influenza virus-infected mice (P1043) ↗The Journal of Immunology · 2013not yet assessed
-
Bystander CD8 T cells produce granzyme B and promote exacerbated disease during <i>Leishmania major</i> infection (P3079) ↗The Journal of Immunology · 2013not yet assessed
-
T cell responses to persisting and non-persisting infectionsIndian Heart Journal · 2013not yet assessed
-
Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity ↗Immunity · 2012 · PMID 22705104not yet assessed
-
Progenitor and Terminal Subsets of CD8 <sup>+</sup> T Cells Cooperate to Contain Chronic Viral Infection ↗Science · 2012 · PMID 23197535not yet assessed
-
Antigen-Independent Differentiation and Maintenance of Effector-like Resident Memory T Cells in Tissues ↗The Journal of Immunology · 2012 · PMID 22504644not yet assessed
-
A Mouse Model of Vitiligo with Focused Epidermal Depigmentation Requires IFN-γ for Autoreactive CD8+ T-Cell Accumulation in the Skin ↗Journal of Investigative Dermatology · 2012 · PMID 22297636not yet assessed
-
Progressive Loss of Memory T Cell Potential and Commitment to Exhaustion during Chronic Viral Infection ↗Journal of Virology · 2012 · PMID 22623779not yet assessed
-
Inhibitory Receptors on Lymphocytes: Insights from Infections ↗The Journal of Immunology · 2012 · PMID 22442493not yet assessed
-
Defective CD8 T Cell Responses in Aged Mice Are Due to Quantitative and Qualitative Changes in Virus-Specific Precursors ↗The Journal of Immunology · 2012 · PMID 22246631not yet assessed
-
Chronic Bystander Infections and Immunity to Unrelated Antigens ↗Cell Host & Microbe · 2012 · PMID 23084915not yet assessed
-
Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes ↗Journal of Leukocyte Biology · 2012 · PMID 23192430not yet assessed
-
Bystander chronic infection negatively impacts the development of CD8 T cell memory (76.6) ↗The Journal of Immunology · 2012not yet assessed
-
Molecular analysis of age-associated B cells (ABCs) (69.7) ↗The Journal of Immunology · 2012not yet assessed
-
Influence of viral specific memory cells on Leishmania major infection (164.12) ↗The Journal of Immunology · 2012not yet assessed
-
Differential localization of T-bet and Eomes within distinct human CD8 T-cell memory populations (110.10) ↗The Journal of Immunology · 2012not yet assessed
-
T cell exhaustion ↗Nature Immunology · 2011 · PMID 21739672not yet assessed
-
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus ↗Nature Immunology · 2011not yet assessed
-
Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus. ↗PubMed · 2011 · PMID 21946417not yet assessed
-
Cutting Edge: Tissue-Retentive Lung Memory CD4 T Cells Mediate Optimal Protection to Respiratory Virus Infection ↗The Journal of Immunology · 2011 · PMID 22058417not yet assessed
-
TSLP promotes interleukin-3-independent basophil haematopoiesis and type 2 inflammation ↗Nature · 2011 · PMID 21841801not yet assessed
-
Transcription factor T-bet represses expression of the inhibitory receptor PD-1 and sustains virus-specific CD8+ T cell responses during chronic infection ↗Nature Immunology · 2011 · PMID 21623380not yet assessed
-
A Role for the Chemokine RANTES in Regulating CD8 T Cell Responses during Chronic Viral Infection ↗PLoS Pathogens · 2011 · PMID 21814510not yet assessed
-
Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells ↗Current Opinion in HIV and AIDS · 2011 · PMID 22134341not yet assessed
-
Protein Energy Malnutrition Impairs Homeostatic Proliferation of Memory CD8 T Cells ↗The Journal of Immunology · 2011 · PMID 22116826not yet assessed
-
Cutting Edge: Persistently Open Chromatin at Effector Gene Loci in Resting Memory CD8+ T Cells Independent of Transcriptional Status ↗The Journal of Immunology · 2011 · PMID 21278341not yet assessed
-
K12/SECTM1, an interferon-γ regulated molecule, synergizes with CD28 to costimulate human T cell proliferation ↗Journal of Leukocyte Biology · 2011 · PMID 22184754not yet assessed
-
The contribution of epigenetic memory to immunologic memory ↗Current Opinion in Genetics & Development · 2011 · PMID 21330128not yet assessed
-
Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88 ↗Blood · 2011 · PMID 21233312not yet assessed
-
Memory T cells generated in youth function well in old age (49.8) ↗The Journal of Immunology · 2011not yet assessed
-
Dynamic T cell migration program provides resident memory within intestinal epithelium ↗The Journal of Experimental Medicine · 2010 · PMID 20156972not yet assessed
-
Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF ↗Nature Medicine · 2010 · PMID 20890291not yet assessed
-
Cutting Edge: The Transcription Factor Eomesodermin Enables CD8+ T Cells To Compete for the Memory Cell Niche ↗The Journal of Immunology · 2010 · PMID 20935204not yet assessed
-
Role of PD-1 in regulating acute infections ↗Current Opinion in Immunology · 2010 · PMID 20427170not yet assessed
-
Increased Programmed Death-1 Expression on CD4+ T Cells in Cutaneous T-Cell Lymphoma ↗Archives of Dermatology · 2010 · PMID 20713771not yet assessed
-
Perforin and IL-2 Upregulation Define Qualitative Differences among Highly Functional Virus-Specific Human CD8+ T Cells ↗PLoS Pathogens · 2010 · PMID 20221423not yet assessed
-
Cell-Intrinsic Defects in the Proliferative Response of Antiviral Memory CD8 T Cells in Aged Mice upon Secondary Infection ↗The Journal of Immunology · 2010 · PMID 20368274not yet assessed
-
T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool ↗Blood · 2010 · PMID 20847203not yet assessed
-
Integrating Genomic Signatures for Immunologic Discovery ↗Immunity · 2010 · PMID 20189480not yet assessed
-
Transcription factor regulation of CD8<sup>+</sup> T‐cell memory and exhaustion ↗Immunological Reviews · 2010 · PMID 20636816not yet assessed
-
Loss of tonic T-cell receptor signals alters the generation but not the persistence of CD8+ memory T cells ↗Blood · 2010 · PMID 20884806not yet assessed
-
TCF-1 Flips the Switch on Eomes ↗Immunity · 2010 · PMID 20732636not yet assessed
-
Editorial overview ↗Current Opinion in Immunology · 2010 · PMID 20537516not yet assessed
-
Unravelling CD4 T cell Dysfunction During Chronic Infection (39.17) ↗The Journal of Immunology · 2010not yet assessed
-
Faculty Opinions recommendation of Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. ↗Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2010not yet assessed
-
Redefining Chronic Viral Infection ↗Cell · 2009 · PMID 19596234not yet assessed
-
A Role for the Transcriptional Repressor Blimp-1 in CD8+ T Cell Exhaustion during Chronic Viral Infection ↗Immunity · 2009 · PMID 19664943not yet assessed
-
Synergistic Reversal of Intrahepatic HCV-Specific CD8 T Cell Exhaustion by Combined PD-1/CTLA-4 Blockade ↗PLoS Pathogens · 2009 · PMID 19247441not yet assessed
-
Behavior of Parasite-Specific Effector CD8+ T Cells in the Brain and Visualization of a Kinesis-Associated System of Reticular Fibers ↗Immunity · 2009 · PMID 19167248not yet assessed
-
Impact of Epitope Escape on PD-1 Expression and CD8 T-Cell Exhaustion during Chronic Infection ↗Journal of Virology · 2009 · PMID 19211743not yet assessed
-
The diversity of costimulatory and inhibitory receptor pathways and the regulation of antiviral T cell responses ↗Current Opinion in Immunology · 2009 · PMID 19264470not yet assessed
-
Tissue-Specific Differences in PD-1 and PD-L1 Expression during Chronic Viral Infection: Implications for CD8 T-Cell Exhaustion ↗Journal of Virology · 2009 · PMID 19955307not yet assessed
-
Plasmacytoid Dendritic Cells Are Dispensable during Primary Influenza Virus Infection ↗The Journal of Immunology · 2009 · PMID 19124730not yet assessed
-
Dynamic decrease in PD-1 expression correlates with HBV-specific memory CD8 T-cell development in acute self-limited hepatitis B patients ↗Journal of Hepatology · 2009 · PMID 19395117not yet assessed
-
not yet assessed
-
Editorial: Therapeutic potential of targeting BTLA ↗Journal of Leukocyte Biology · 2009 · PMID 19567411not yet assessed
-
Faculty Opinions recommendation of Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals. ↗Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2009not yet assessed
-
Novel roles for T-bet in CD8 differentiation during chronic viral infections (44.8) ↗The Journal of Immunology · 2009not yet assessed
-
not yet assessed
-
Faculty Opinions recommendation of T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes. ↗Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2009not yet assessed
-
Faculty Opinions recommendation of Neutralizing antibodies derived from the B cells of 1918 influenza pandemic survivors. ↗Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2009not yet assessed
-
Faculty Opinions recommendation of Inhibitory receptor signaling via tyrosine phosphorylation of the adaptor Crk. ↗Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2009not yet assessed
-
Poor anti-viral immunity in aged mice is associated with defects in CD8 T cell recall responses (44.5) ↗The Journal of Immunology · 2009not yet assessed
-
Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection ↗Nature Immunology · 2008 · PMID 19043418not yet assessed
-
Selective expansion of a subset of exhausted CD8 T cells by αPD-L1 blockade ↗Proceedings of the National Academy of Sciences · 2008 · PMID 18809920not yet assessed
-
Anomalous Type 17 Response to Viral Infection by CD8 <sup>+</sup> T Cells Lacking T-bet and Eomesodermin ↗Science · 2008 · PMID 18635804not yet assessed
-
Functional Restoration of HCV-Specific CD8 T Cells by PD-1 Blockade Is Defined by PD-1 Expression and Compartmentalization ↗Gastroenterology · 2008 · PMID 18549878not yet assessed
-
Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection ↗The Journal of Experimental Medicine · 2008 · PMID 18332181not yet assessed
-
Dynamic Programmed Death 1 Expression by Virus-Specific CD8 T Cells Correlates With the Outcome of Acute Hepatitis B ↗Gastroenterology · 2008 · PMID 18455515not yet assessed
-
Targeting of antigen to the herpesvirus entry mediator augments primary adaptive immune responses ↗Nature Medicine · 2008 · PMID 18193057not yet assessed
-
MyD88 Plays a Critical T Cell-Intrinsic Role in Supporting CD8 T Cell Expansion during Acute Lymphocytic Choriomeningitis Virus Infection ↗The Journal of Immunology · 2008 · PMID 18768833not yet assessed
-
Identification of an Evolutionarily Conserved Transcriptional Signature of CD8 Memory Differentiation That Is Shared by T and B Cells ↗The Journal of Immunology · 2008 · PMID 18641323not yet assessed
-
Diminished Primary CD8 T Cell Response to Viral Infection during Protein Energy Malnutrition in Mice Is Due to Changes in Microenvironment and Low Numbers of Viral-Specific CD8 T Cell Precursors3 ↗Journal of Nutrition · 2008 · PMID 18356339not yet assessed
-
A distinct role for T‐bet in the maintenance of antigen‐specific CD8 T‐cells during chronic viral infection ↗The FASEB Journal · 2008not yet assessed
-
T cell migration and memory differentiation within the mouse intestinal mucosa in response to infection ↗The FASEB Journal · 2008not yet assessed
-
Examining age‐related function and phenotype of influenza‐specific CD8+T cells in humans ↗The FASEB Journal · 2008not yet assessed
-
Compromised CD8 T cell recall responses in the aged mice ↗The FASEB Journal · 2008not yet assessed
-
Non‐antigenic signals alter memory CD8 T cell development during chronic infection ↗The FASEB Journal · 2008not yet assessed
-
Defining the phenotype, function and differentiation state of CD4 T cells during chronic infection ↗The FASEB Journal · 2008not yet assessed
-
Molecular Signature of CD8+ T Cell Exhaustion during Chronic Viral Infection ↗Immunity · 2007 · PMID 17950003not yet assessed
-
The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection ↗Nature Immunology · 2007 · PMID 17304234not yet assessed
-
not yet assessed
-
Heterogeneity and Cell-Fate Decisions in Effector and Memory CD8+ T Cell Differentiation during Viral Infection ↗Immunity · 2007 · PMID 17892848not yet assessed
-
CD8 T cell dysfunction during chronic viral infection ↗Current Opinion in Immunology · 2007 · PMID 17656078not yet assessed
-
Requirement for T-bet in the aberrant differentiation of unhelped memory CD8+ T cells ↗The Journal of Experimental Medicine · 2007 · PMID 17698591not yet assessed
-
Viral antigen and extensive division maintain virus-specific CD8 T cells during chronic infection ↗The Journal of Experimental Medicine · 2007 · PMID 17420267not yet assessed
-
IL-10, T cell exhaustion and viral persistence ↗Trends in Microbiology · 2007 · PMID 17336072not yet assessed
-
Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: implications for their use as vaccines ↗Blood · 2007 · PMID 17510320not yet assessed
-
Strength of Stimulus and Clonal Competition Impact the Rate of Memory CD8 T Cell Differentiation ↗The Journal of Immunology · 2007 · PMID 17982060not yet assessed
-
Inhibitory receptors: whose side are they on? ↗Nature Immunology · 2007 · PMID 17952048not yet assessed
-
Requirement for T-bet in the aberrant differentiation of unhelped memory CD8<sup>+</sup>T cells ↗The Journal of Cell Biology · 2007not yet assessed
-
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression ↗Nature · 2006 · PMID 16921384not yet assessed
-
Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression ↗Journal of Virology · 2006 · PMID 17182670not yet assessed
-
Reinvigorating exhausted HIV-specific T cells via PD-1–PD-1 ligand blockade ↗The Journal of Experimental Medicine · 2006 · PMID 17000870not yet assessed
-
Cutting Edge: Gut Microenvironment Promotes Differentiation of a Unique Memory CD8 T Cell Population ↗The Journal of Immunology · 2006 · PMID 16455963not yet assessed
-
Cutting Edge: IL-12 Inversely Regulates T-bet and Eomesodermin Expression during Pathogen-Induced CD8+ T Cell Differentiation ↗The Journal of Immunology · 2006 · PMID 17114419not yet assessed
-
Turning on the off switch: Regulation of anti-viral T cell responses in the liver by the PD-1/PD-L1 pathway ↗Journal of Hepatology · 2006 · PMID 16901572not yet assessed
-
HIV-specific CD8 T cells express low levels of IL-7Rα: Implications for HIV-specific T cell memory ↗Virology · 2006 · PMID 16860834not yet assessed
-
Hypogammaglobulinemia and exacerbated CD8 T-cell–mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease ↗Blood · 2006 · PMID 16788096not yet assessed
-
Re-evaluating the Generation of a “Proteasome-Independent” MHC Class I-Restricted CD8 T Cell Epitope ↗The Journal of Immunology · 2006 · PMID 16455981not yet assessed
-
Not‐so‐great expectations: re‐assessing the essence of T‐cell memory ↗Immunological Reviews · 2006 · PMID 16824129not yet assessed
-
Su.66. Memory T-Cells in Mice and Humans Share a Common Molecular Program of Differentiation Regardless of Phenotype, Lineage Or Species ↗Clinical Immunology · 2006not yet assessed
-
Transcriptional mapping of the anti-viral T cell response shows that impaired memory differentiation causes T cell dysfunction ↗Transplantation and Cellular Therapy · 2006not yet assessed
-
not yet assessed
-
Restoring function in exhausted CD8 T cells during chronic viral infection ↗Nature · 2005 · PMID 16382236not yet assessed
-
Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin ↗Nature Immunology · 2005 · PMID 16273099not yet assessed
-
Bone Marrow Is a Preferred Site for Homeostatic Proliferation of Memory CD8 T Cells ↗The Journal of Immunology · 2005 · PMID 15661882not yet assessed
-
Low CD8 T-Cell Proliferative Potential and High Viral Load Limit the Effectiveness of Therapeutic Vaccination ↗Journal of Virology · 2005 · PMID 15994790not yet assessed
-
Differentiation of CD8 T Cells in Response to Acute and Chronic Viral Infections: Implications for HIV Vaccine Development ↗Current Drug Targets - Infectious Disorders · 2005 · PMID 15975018not yet assessed
-
Erratum: Corrigendum: Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin ↗Nature Immunology · 2005not yet assessed
-
Transcriptional Mapping of T Cell Memory Reveals That Chronic Viral Infection Arrests Memory Differentiation. ↗Blood · 2005not yet assessed
-
Memory CD8 T-Cell Differentiation during Viral Infection ↗Journal of Virology · 2004 · PMID 15140950not yet assessed
-
Antigen-independent memory CD8 T cells do not develop during chronic viral infection ↗Proceedings of the National Academy of Sciences · 2004 · PMID 15505208not yet assessed
-
Generation and maintenance of immunological memory ↗Seminars in Immunology · 2004 · PMID 15528077not yet assessed
-
The role of programming in memory T-cell development ↗Current Opinion in Immunology · 2004 · PMID 15023416not yet assessed
-
Viral FLIP Impairs Survival of Activated T Cells and Generation of CD8+ T Cell Memory ↗The Journal of Immunology · 2004 · PMID 15128821not yet assessed
-
Lineage relationship and protective immunity of memory CD8 T cell subsets ↗Nature Immunology · 2003 · PMID 12563257not yet assessed
-
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells ↗Nature Immunology · 2003 · PMID 14625547not yet assessed
-
Viral Persistence Alters CD8 T-Cell Immunodominance and Tissue Distribution and Results in Distinct Stages of Functional Impairment ↗Journal of Virology · 2003 · PMID 12663797not yet assessed
-
Heterologous immunity provides a potent barrier to transplantation tolerance ↗Journal of Clinical Investigation · 2003 · PMID 12813024not yet assessed
-
Heterologous immunity provides a potent barrier to transplantation tolerance ↗Journal of Clinical Investigation · 2003not yet assessed
-
Cutting Edge: Rapid In Vivo Killing by Memory CD8 T Cells ↗The Journal of Immunology · 2003 · PMID 12816979not yet assessed
-
Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo ↗Nature Medicine · 2003 · PMID 12692546not yet assessed
-
TCR Signal Transduction in Antigen-Specific Memory CD8 T Cells ↗The Journal of Immunology · 2003 · PMID 12759421not yet assessed
-
Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation ↗Virology · 2003 · PMID 14592762not yet assessed
-
Cytosolic Delivery of Viral Nucleoprotein by Listeriolysin O-Liposome Induces Enhanced Specific Cytotoxic T Lymphocyte Response and Protective Immunity ↗Molecular Pharmaceutics · 2003 · PMID 15832496not yet assessed
-
Use of Vaccinia Virus Expression Vectors to Investigate Antigen Processing and Presentation ↗Humana Press eBooks · 2003 · PMID 11068753not yet assessed
-
Effector and memory T-cell differentiation: implications for vaccine development ↗Nature reviews. Immunology · 2002 · PMID 12001996not yet assessed
-
Interleukin 15 Is Required for Proliferative Renewal of Virus-specific Memory CD8 T Cells ↗The Journal of Experimental Medicine · 2002 · PMID 12070282not yet assessed
-
Differential Sensitivity of Naive and Memory CD8+ T Cells to Apoptosis in Vivo ↗The Journal of Immunology · 2002 · PMID 12244170not yet assessed
-
Generation of CD8+ T Cell Memory in Response to Low, High, and Excessive Levels of Epitope ↗The Journal of Immunology · 2002 · PMID 11970989not yet assessed
-
Homeostatic Proliferation But not The Generation of Virus Specific Memory CD8 T Cells is Impaired in the Absence of IL-15 or IL-15Rα ↗Advances in experimental medicine and biology · 2002 · PMID 12405201not yet assessed
-
Efficient and Qualitatively Distinct MHC Class I-Restricted Presentation of Antigen Targeted to the Endoplasmic Reticulum ↗The Journal of Immunology · 2002 · PMID 11884431not yet assessed
-
The Induction of Virus-Specific CTL as a Function of Increasing Epitope Expression: Responses Rise Steadily Until Excessively High Levels of Epitope Are Attained ↗The Journal of Immunology · 1999not yet assessed
-
Point mutation flanking a CTL epitope ablates in vitro and in vivo recognition of a full-length viral protein ↗The Journal of Immunology · 1997 · PMID 9120278not yet assessed
-
Our Temperate Tufted Polemoniums ↗Aliso · 1967not yet assessed
-
Remarks on the Genus Linanthus ↗Aliso · 1961not yet assessed
-
Remarks on the Ipomopsis Aggregata Group ↗Aliso · 1961not yet assessed
Full bibliography from OpenAlex; reproducibility verdicts matched by PMID.
Author attribution follows OpenAlex disambiguation, which is imperfect — a researcher's papers can be split across profiles or mixed with a namesake.
Merged across profiles sharing this ORCID where present. See every “Wherry E” paper on PubMed ↗