Sally A. Cowley

The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.

Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.

How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.

Assessed papers (2)

• Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models.
  2022 L1 100/100
• Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes.⚑
  2018 L1 30/100 ⚑

2 assessed by us (1 reproduced) · 171 not yet assessed — every PubMed paper on record, linked below.

• Single-cell resolution uncovers cell type-specific dysregulation in Parkin-deficient neuron-microglia co-cultures ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2026
  not yet assessed
• Single-cell and spatial transcriptomic analyses of gene therapy-associated retinal inflammation in non-human primates ↗

  Molecular Therapy Advances · 2026
  not yet assessed
• Tracking tau and cellular responses in human iPSC‐microglia: from uptake to seedable secretion, including in extracellular vesicles ↗

  Alzheimer s & Dementia · 2026 · PMID 41943483
  not yet assessed
• New Human IPSC Models of Late-onset Alzheimer’s Disease Polygenic Risk Identify Multiple Impairments of Microglial Function ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2026
  not yet assessed
• Deconvolving the structural heterogeneity of alpha-Synuclein in <i>vitro</i> and <i>in situ</i> ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2026
  not yet assessed
• Reactive astrocytes mediate toxicity in iPSC derived dopaminergic neurons ↗

  npj Parkinson s Disease · 2026 · PMID 42285981
  not yet assessed
• TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen ↗

  Nature Communications · 2025 · PMID 39747086
  not yet assessed
• Cytoskeletal control in adult microglia is essential to restore neurodevelopmental synaptic and cognitive deficits ↗

  Science Advances · 2025 · PMID 40880479
  not yet assessed
• Modeling common Alzheimer’s disease with high and low polygenic risk in human iPSC: A large-scale research resource ↗

  Stem Cell Reports · 2025 · PMID 40614728
  not yet assessed
• Cerebellar organoids model cell type-specific <i>FOXP2</i> expression during human cerebellar development ↗

  Disease Models & Mechanisms · 2025 · PMID 41236144
  not yet assessed
• Differences in neuronal ciliation rate and ciliary content revealed by systematic imaging-based analysis of hiPSC-derived models across protocols ↗

  Frontiers in Cell and Developmental Biology · 2025 · PMID 40292331
  not yet assessed
• Protocol for pooled FACS-based CRISPR knockout screening in human iPSC-derived microglia ↗

  STAR Protocols · 2025 · PMID 40975871
  not yet assessed
• Evidence for enhancer activity in intron 1 of TNFRSF1A using CRISPR/Cas9 in human induced pluripotent stem cell-derived macrophages ↗

  Scientific Reports · 2025 · PMID 41057395
  not yet assessed
• USP30 inhibition improves mitochondrial health through both PINK1-dependent and independent mechanisms ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025
  not yet assessed
• Integrated QTL mapping and CRISPR screening in pooled iPSC-derived microglia reveals genetic drivers of neurodegenerative risk ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025
  not yet assessed
• Tracking tau and cellular responses in human iPSC-microglia from uptake to seedable secretion in extracellular vesicles ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025
  not yet assessed
• TFEB and TFE3 have cell-type specific expression in the brain and divergent roles in neurons ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025
  not yet assessed
• ABS0297 RAPID ACCESS MICROSCOPY AND REAL TIME CASE DISCUSSION VIA A SECURE MESSAGING APP IMPROVES DIAGNOSTIC ACCURACY AND MANAGEMENT OF ACUTE HOT SWOLLEN JOINTS ↗

  Annals of the Rheumatic Diseases · 2025
  not yet assessed
• Single-cell and spatial transcriptomic analyses of gene therapy-associated retinal inflammation in non-human primates ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2025 · PMID 42137601
  not yet assessed
• Understanding the role of Aβ and Tau in neuronal vulnerability in models of sporadic Alzheimer's disease ↗

  Alzheimer s & Dementia · 2025 · PMID 41435876
  not yet assessed
• <i>PTCH1</i> -mutant human cerebellar organoids exhibit altered neural development and recapitulate early medulloblastoma tumorigenesis ↗

  Disease Models & Mechanisms · 2024 · PMID 38411252
  not yet assessed
• Systematic identification of structure-specific protein–protein interactions ↗

  Molecular Systems Biology · 2024 · PMID 38702390
  not yet assessed
• Tau depletion in human neurons mitigates Aβ-driven toxicity ↗

  Molecular Psychiatry · 2024 · PMID 38361127
  not yet assessed
• Tapasin assembly surveillance by the RNF185/Membralin ubiquitin ligase complex regulates MHC-I surface expression ↗

  Nature Communications · 2024 · PMID 39353943
  not yet assessed
• Optical genome mapping of structural variants in Parkinson’s disease-related induced pluripotent stem cells ↗

  BMC Genomics · 2024 · PMID 39425080
  not yet assessed
• TransLeish: Identification of membrane transporters essential for survival of intracellular <i>Leishmania</i> parasites in a systematic gene deletion screen ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2024
  not yet assessed
• Cerebellar organoids model cell type-specific <i>FOXP2</i> expression during human cerebellar development ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2024
  not yet assessed
• C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9 ↗

  Nature Communications · 2023 · PMID 37736756
  not yet assessed
• Post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease GBA-N370S dopamine neurons ↗

  Cell Reports · 2023 · PMID 36870058
  not yet assessed
• Calcium dysregulation combined with mitochondrial failure and electrophysiological maturity converge in Parkinson’s iPSC-dopamine neurons ↗

  iScience · 2023 · PMID 37426342
  not yet assessed
• Integration of 3D-printed cerebral cortical tissue into an ex vivo lesioned brain slice ↗

  Nature Communications · 2023 · PMID 37794031
  not yet assessed
• Systematic identification of structure-specific protein–protein interactions ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2023
  not yet assessed
• <i>PTCH1</i> mutant human cerebellar organoids are associated with altered neural development and early pathways of medulloblastoma oncogenesis ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2023
  not yet assessed
• NON-CELL AUTONOMOUS INDUCTION OF A CANCER STEM CELL MOLECULAR PHENOTYPE IN AN IN VITRO MODEL OF SONIC HEDGEHOG MEDULLOBLASTOMA ↗

  Neuro-Oncology · 2023
  not yet assessed
• Human microglia, microglial LRRK2, and tau pathogenesis: a complex relationship ↗

  Alzheimer s & Dementia · 2023
  not yet assessed
• Genome‐wide CRISPR knockout screening to identify key regulators of phagocytosis in induced pluripotent stem cell derived microglia ↗

  Alzheimer s & Dementia · 2023
  not yet assessed
• Role of peripheral inflammation in driving central nervous system inflammatory signature in pathogenesis of Alzheimer’s disease ↗

  Alzheimer s & Dementia · 2023
  not yet assessed
• Microglia states and nomenclature: A field at its crossroads ↗

  Neuron · 2022 · PMID 36327895
  not yet assessed
• Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality ↗

  Glia · 2022 · PMID 35262217
  not yet assessed
• Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSC to microglia ↗

  Scientific Reports · 2022 · PMID 36376339
  not yet assessed
• Aberrant inflammatory responses to type I interferon in STAT2 or IRF9 deficiency ↗

  Journal of Allergy and Clinical Immunology · 2022 · PMID 35182547
  not yet assessed
• Human iPSC co-culture model to investigate the interaction between microglia and motor neurons ↗

  Scientific Reports · 2022 · PMID 35871163
  not yet assessed
• Pathogenic LRRK2 regulates centrosome cohesion via Rab10/RILPL1-mediated CDK5RAP2 displacement ↗

  iScience · 2022 · PMID 35721463
  not yet assessed
• Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models

  Disease Models & Mechanisms · 2022 · PMID 36254682
  L1 100/100
• Radical-SAM dependent nucleotide dehydratase (SAND), rectification of the names of an ancient iron-sulfur enzyme using NC-IUBMB recommendations ↗

  Frontiers in Molecular Biosciences · 2022 · PMID 36387278
  not yet assessed
• Type I interferon receptor (IFNAR2) deficiency reveals Zika virus cytopathicity in human macrophages and microglia ↗

  Frontiers in Immunology · 2022 · PMID 36439115
  not yet assessed
• The role of human microglia and microglial LRRK2 in tau pathogenesis ↗

  Alzheimer s & Dementia · 2022
  not yet assessed
• Defining Microglial States and Nomenclature: A Roadmap to 2030 ↗

  SSRN Electronic Journal · 2022
  not yet assessed
• Microglia integration into human midbrain organoids leads to increased neuronal maturation and functionality ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Single-cell transcriptomics defines an improved, validated monoculture protocol for differentiation of human iPSCs to microglia ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Type I interferons govern Zika virus resistance of human macrophages and microglia ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Modelling SHH-Medulloblastoma Using Cerebellar Organoids ↗

  Neuro-Oncology · 2022
  not yet assessed
• Tau depletion in human neurons mitigates Aβ-driven toxicity ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Functional Integration of 3D-Printed Cerebral Cortical Tissue into a Brain Lesion ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Non-neuronal cells in amyotrophic lateral sclerosis — from pathogenesis to biomarkers ↗

  Nature Reviews Neurology · 2021 · PMID 33927394
  not yet assessed
• Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart ↗

  Development · 2021 · PMID 33462113
  not yet assessed
• Alzheimer’s Risk Gene TREM2 Determines Functional Properties of New Type of Human iPSC-Derived Microglia ↗

  Frontiers in Immunology · 2021 · PMID 33613545
  not yet assessed
• Gene therapy restores dopamine transporter expression and ameliorates pathology in iPSC and mouse models of infantile parkinsonism ↗

  Science Translational Medicine · 2021 · PMID 34011628
  not yet assessed
• Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium ↗

  Stem Cell Reports · 2021 · PMID 34171284
  not yet assessed
• Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages ↗

  Scientific Reports · 2021 · PMID 33608581
  not yet assessed
• Identification of bioactive metabolites in human iPSC-derived dopaminergic neurons with PARK2 mutation: Altered mitochondrial and energy metabolism ↗

  Stem Cell Reports · 2021 · PMID 34048689
  not yet assessed
• iPSC-Derived Microglia as a Model to Study Inflammation in Idiopathic Parkinson’s Disease ↗

  Frontiers in Cell and Developmental Biology · 2021 · PMID 34805149
  not yet assessed
• Molecular and electrophysiological features of spinocerebellar ataxia type seven in induced pluripotent stem cells ↗

  PLoS ONE · 2021 · PMID 33626063
  not yet assessed
• In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages ↗

  Journal of Visualized Experiments · 2021
  not yet assessed
• In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages ↗

  Journal of Visualized Experiments · 2021 · PMID 33645588
  not yet assessed
• Differentiation of human induced pluripotent stem cells to authentic macrophages using a defined, serum-free, open-source medium ↗

  Stem Cell Reports · 2021 · PMID 34910900
  not yet assessed
• A novel post-translational proteomics platform identifies neurite outgrowth impairments in Parkinson’s disease <i>GBA-N370S</i> dopamine neurons ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2021
  not yet assessed
• Variation on a theme: mapping microglial heterogeneity ↗

  Trends in Genetics · 2021 · PMID 34563398
  not yet assessed
• Large-Scale Production of Human iPSC-Derived Macrophages for Drug Screening ↗

  International Journal of Molecular Sciences · 2020 · PMID 32645954
  not yet assessed
• Impairment of Mitochondrial Calcium Buffering Links Mutations in C9ORF72 and TARDBP in iPS-Derived Motor Neurons from Patients with ALS/FTD ↗

  Stem Cell Reports · 2020 · PMID 32330447
  not yet assessed
• LRRK2 Is Recruited to Phagosomes and Co-recruits RAB8 and RAB10 in Human Pluripotent Stem Cell-Derived Macrophages ↗

  Stem Cell Reports · 2020 · PMID 32359446
  not yet assessed
• TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages ↗

  Alzheimer s Research & Therapy · 2020 · PMID 33198789
  not yet assessed
• ADAM17‐triggered TNF signalling protects the ageing Drosophila retina from lipid droplet‐mediated degeneration ↗

  The EMBO Journal · 2020 · PMID 32715522
  not yet assessed
• Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder ↗

  Molecular Psychiatry · 2020 · PMID 32404948
  not yet assessed
• Honing the Double-Edged Sword: Improving Human iPSC-Microglia Models ↗

  Frontiers in Immunology · 2020 · PMID 33363548
  not yet assessed
• Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936 ↗

  Stem Cell Research · 2020 · PMID 32450543
  not yet assessed
• Profiling of naïve and primed human pluripotent stem cells reveals state-associated miRNAs ↗

  Scientific Reports · 2020 · PMID 32601281
  not yet assessed
• Rates of homology directed repair of CRISPR-Cas9 induced double strand breaks are lower in naïve compared to primed human pluripotent stem cells ↗

  Stem Cell Research · 2020 · PMID 32521498
  not yet assessed
• TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to TREM2 knockout in human IPSC‐derived macrophages ↗

  Alzheimer s & Dementia · 2020
  not yet assessed
• Targeting SHIP1 for therapeutic intervention in Alzheimer’s disease ↗

  Alzheimer s & Dementia · 2020
  not yet assessed
• Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in C9orf72 by CRISPR/Cas9 genome editing using homology-directed repair ↗

  Human Molecular Genetics · 2020 · PMID 32504093
  not yet assessed
• Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• ADAM17-triggered TNF signalling protects the ageing Drosophila retina from lipid droplet mediated degeneration ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• Generation of twenty four induced pluripotent stem cell lines from twenty four members of the Lothian Birth Cohort 1936 ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• A chemical tool for improved culture of human pluripotent stem cells ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• Differentiation of Human induced Pluripotent Stem Cells to Authentic Macrophages using Fully Defined, Serum Free, Open Source Media ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2020
  not yet assessed
• Investigating amyloid beta‐induced toxicity in tau‐deficient human neurons ↗

  Alzheimer s & Dementia · 2020
  not yet assessed
• TREM2 knockout, but not the R47H Alzheimer’s variant, reduces neural phagocytosis and survival of human iPSC-derived macrophages ↗

  Research Square · 2020
  not yet assessed
• Additional file 1 of TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages ↗

  Figshare · 2020
  not yet assessed
• Additional file 4 of TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages ↗

  Figshare · 2020
  not yet assessed
• Additional file 5 of TREM2 Alzheimer’s variant R47H causes similar transcriptional dysregulation to knockout, yet only subtle functional phenotypes in human iPSC-derived macrophages ↗

  Figshare · 2020
  not yet assessed
• Cellular α-synuclein pathology is associated with bioenergetic dysfunction in Parkinson’s iPSC-derived dopamine neurons ↗

  Human Molecular Genetics · 2019 · PMID 30753527
  not yet assessed
• Microglial inflammation and phagocytosis in Alzheimer's disease: Potential therapeutic targets ↗

  British Journal of Pharmacology · 2019 · PMID 30740661
  not yet assessed
• An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2 ↗

  Neurobiology of Disease · 2019 · PMID 30954703
  not yet assessed
• RNA sequencing reveals MMP2 and TGFB1 downregulation in LRRK2 G2019S Parkinson's iPSC-derived astrocytes ↗

  Neurobiology of Disease · 2019 · PMID 31085228
  not yet assessed
• A causal role for TRESK loss of function in migraine mechanisms ↗

  Brain · 2019 · PMID 31742594
  not yet assessed
• Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers ↗

  Journal of Biological Chemistry · 2019 · PMID 30872401
  not yet assessed
• Application of CRISPR/Cas9 editing and digital droplet PCR in human iPSCs to generate novel knock-in reporter lines to visualize dopaminergic neurons ↗

  Stem Cell Research · 2019 · PMID 31733438
  not yet assessed
• LRRK2 is recruited to phagosomes and co-recruits Rab8 and Rab10 in human pluripotent stem cell-derived macrophages ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2019
  not yet assessed
• Correction of amyotrophic lateral sclerosis related phenotypes in induced pluripotent stem cell-derived motor neurons carrying a hexanucleotide expansion mutation in <i>C9orf72</i> by CRISPR/Cas9 genome editing using homology-directed repair ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2019
  not yet assessed
• An integrated transcriptomics and proteomics analysis reveals functional endocytic dysregulation caused by mutations in LRRK2

  Oxford University Research Archive (ORA) (University of Oxford) · 2019
  not yet assessed
• Targeting SHIP1 for therapeutic intervention in Alzheimer's disease

  Glia · 2019
  not yet assessed
• Gene Therapy for Infantile Parkinsonism

  Molecular Therapy · 2019
  not yet assessed
• A mass spectrometry-based screen reveals FRMD8 as a novel regulator of iRhom/ADAM17-dependent inflammatory and growth factor signalling.

  Oxford University Research Archive (ORA) (University of Oxford) · 2019
  not yet assessed
• Using human iPSC derived dopamine neurons to investigate physiological changes in Parkinson Disease

  Acta Physiologica · 2019
  not yet assessed
• Single-Cell Sequencing of iPSC-Dopamine Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes⚑

  Cell stem cell · 2018 · PMID 30503143
  L1 30/100 ⚑
• LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages ↗

  The EMBO Journal · 2018 · PMID 29789389
  not yet assessed
• FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex ↗

  eLife · 2018 · PMID 29897336
  not yet assessed
• A Simplified Method for Generating Purkinje Cells from Human-Induced Pluripotent Stem Cells ↗

  The Cerebellum · 2018 · PMID 29397531
  not yet assessed
• Genome editing in induced pluripotent stem cells rescues <i>TAF1</i> levels in X‐linked dystonia‐parkinsonism ↗

  Movement Disorders · 2018 · PMID 30153385
  not yet assessed
• Neurodegeneration in SCA14 is associated with increased PKCγ kinase activity, mislocalization and aggregation ↗

  Acta Neuropathologica Communications · 2018 · PMID 30249303
  not yet assessed
• RIPK1 is a critical modulator of both tonic and TLR-responsive inflammatory and cell death pathways in human macrophage differentiation ↗

  Cell Death and Disease · 2018 · PMID 30250197
  not yet assessed
• Stem cell modeling of mitochondrial parkinsonism reveals key functions of OPA1 ↗

  Annals of Neurology · 2018 · PMID 29604226
  not yet assessed
• Lentiviral gene therapy vector with UCOE stably restores function in iPSC-derived neutrophils of a CDG patient ↗

  Matters · 2018 · PMID 31008103
  not yet assessed
• Author response: FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex ↗

  2018
  not yet assessed
• FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2018
  not yet assessed
• A Highly Efficient Human Pluripotent Stem Cell Microglia Model Displays a Neuronal-Co-culture-Specific Expression Profile and Inflammatory Response ↗

  Stem Cell Reports · 2017 · PMID 28591653
  not yet assessed
• Alpha-synuclein induces the unfolded protein response in Parkinson’s disease SNCA triplication iPSC-derived neurons ↗

  Human Molecular Genetics · 2017 · PMID 28973645
  not yet assessed
• Excess α-synuclein compromises phagocytosis in iPSC-derived macrophages ↗

  Scientific Reports · 2017 · PMID 28827786
  not yet assessed
• LRRK2 in peripheral and central nervous system innate immunity: its link to Parkinson's disease ↗

  Biochemical Society Transactions · 2017 · PMID 28202666
  not yet assessed
• MAPT Genetic Variation and Neuronal Maturity Alter Isoform Expression Affecting Axonal Transport in iPSC-Derived Dopamine Neurons ↗

  Stem Cell Reports · 2017 · PMID 28689993
  not yet assessed
• Multiplex High-Throughput Targeted Proteomic Assay To Identify Induced Pluripotent Stem Cells ↗

  Analytical Chemistry · 2017 · PMID 28192931
  not yet assessed
• [O2–03–04]: <i>MAPT</i> GENETIC VARIATION AND NEURONAL MATURITY ALTER ISOFORM EXPRESSION AFFECTING AXONAL TRANSPORT IN IPSC‐DERIVED NEURONS ↗

  Alzheimer s & Dementia · 2017
  not yet assessed
• Global proteomic and transcriptomic analysis of the LRRK2 G2019S mutation in iPSC-derived midbrain dopaminergic neurons

  2017
  not yet assessed
• ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons ↗

  Stem Cell Reports · 2016 · PMID 26905200
  not yet assessed
• <i>C9orf72</i> Hexanucleotide Expansions Are Associated with Altered Endoplasmic Reticulum Calcium Homeostasis and Stress Granule Formation in Induced Pluripotent Stem Cell-Derived Neurons from Patients with Amyotrophic Lateral Sclerosis and Frontotemporal Dementia ↗

  Stem Cells · 2016 · PMID 27097283
  not yet assessed
• A novel real time imaging platform to quantify macrophage phagocytosis ↗

  Biochemical Pharmacology · 2016 · PMID 27475716
  not yet assessed
• Assessing similarity to primary tissue and cortical layer identity in induced pluripotent stem cell-derived cortical neurons through single-cell transcriptomics ↗

  Human Molecular Genetics · 2016 · PMID 26740550
  not yet assessed
• Transcriptomic profiling of purified patient-derived dopamine neurons identifies convergent perturbations and therapeutics for Parkinson’s disease ↗

  Human Molecular Genetics · 2016 · PMID 28096185
  not yet assessed
• Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease ↗

  Nucleic Acids Research · 2016 · PMID 27536002
  not yet assessed
• S3‐02‐03: Modelling Microglia with Human Pluripotent Stem Cells ↗

  Alzheimer s & Dementia · 2016
  not yet assessed
• CRISPR-mediated genotypic and phenotypic correction of a chronic granulomatous disease mutation in human iPS cells ↗

  Experimental Hematology · 2015 · PMID 26101162
  not yet assessed
• The Current State of Naïve Human Pluripotency ↗

  Stem Cells · 2015 · PMID 26119873
  not yet assessed
• Modelling amyotrophic lateral sclerosis (ALS) using mutant and CAS9/CRISPR-corrected motor neurons from patients with C9ORF72 mutations reveals disease-specific cellular phenotypes ↗

  Journal of the Neurological Sciences · 2015
  not yet assessed
• Physiological Characterisation of Human iPS-Derived Dopaminergic Neurons ↗

  PLoS ONE · 2014 · PMID 24586273
  not yet assessed
• The Productive Entry Pathway of HIV-1 in Macrophages Is Dependent on Endocytosis through Lipid Rafts Containing CD4 ↗

  PLoS ONE · 2014 · PMID 24465876
  not yet assessed
• C9orf72 Hexanucleotide Expansion Mutations Alter Calcium Signalling in ALS-FTD Patient iPSC-Derived Motor Neurons

  Annals of Neurology · 2014
  not yet assessed
• Efficient, Long Term Production of Monocyte-Derived Macrophages from Human Pluripotent Stem Cells under Partly-Defined and Fully-Defined Conditions ↗

  PLoS ONE · 2013 · PMID 23951090
  not yet assessed
• Human artificial chromosomes maintained in human embryonic stem and neuronal cells

  UCL Discovery (University College London) · 2013
  not yet assessed
• Derivation and Functional Analysis of Patient-Specific Induced Pluripotent Stem Cells as an In Vitro Model of Chronic Granulomatous Disease ↗

  Stem Cells · 2012 · PMID 22311747
  not yet assessed
• Cellular reprogramming: a new approach to modelling Parkinson's disease ↗

  Biochemical Society Transactions · 2012 · PMID 22988881
  not yet assessed
• Differentially expressed, variant U1 snRNAs regulate gene expression in human cells ↗

  Genome Research · 2012 · PMID 23070852
  not yet assessed
• Prevention of silencing by UCOE deletion constructs

  Oxford University Research Archive (ORA) (University of Oxford) · 2012
  not yet assessed
• Transportin 3 Promotes a Nuclear Maturation Step Required for Efficient HIV-1 Integration ↗

  PLoS Pathogens · 2011 · PMID 21901095
  not yet assessed
• Functional human artificial chromosomes are generated and stably maintained in human embryonic stem cells ↗

  Human Molecular Genetics · 2011 · PMID 21593218
  not yet assessed
• Protein Kinase C and NF-κB–Dependent CD4 Downregulation in Macrophages Induced by T Cell-Derived Soluble Factors: Consequences for HIV-1 Infection ↗

  The Journal of Immunology · 2011 · PMID 21666058
  not yet assessed
• Episomal Transgene Expression in Pluripotent Stem Cells ↗

  Methods in molecular biology · 2011 · PMID 21822889
  not yet assessed
• Induced Pluripotent Stem Cells and Their Application to Personalized Therapy ↗

  Elsevier eBooks · 2011
  not yet assessed
• Transportin HIV-1 by tRNAin and CAr ↗

  Retrovirology · 2011
  not yet assessed
• The roles of apoptotic pathways in the low recovery rate after cryopreservation of dissociated human embryonic stem cells ↗

  Biotechnology Progress · 2010 · PMID 20077485
  not yet assessed
• Derivation and characterisation of the human embryonic stem cell line, OxF1 ↗

  In Vitro Cellular & Developmental Biology - Animal · 2010 · PMID 20333479
  not yet assessed
• A2UCOE Lentiviral Vector Resists DNA Methylation-Mediated Silencing, Conferring Long-Term Expression in HSCs Following Serial Transplantation In Vivo

  Human Gene Therapy · 2010
  not yet assessed
• Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation ↗

  Biotechnology Progress · 2009 · PMID 20014103
  not yet assessed
• Homogeneous monocytes and macrophages from human embryonic stem cells following coculture-free differentiation in M-CSF and IL-3 ↗

  Experimental Hematology · 2008 · PMID 18550257
  not yet assessed
• The biology of HIV infection ↗

  Leprosy Review · 2001 · PMID 11495453
  not yet assessed
• Regulation of GATA-2 Phosphorylation by Mitogen-activated Protein Kinase and Interleukin-3 ↗

  Journal of Biological Chemistry · 1995 · PMID 7876160
  not yet assessed
• [29] Assay and expression of mitogen-activated protein kinase, MAP kinase kinase, and Raf ↗

  Methods in enzymology on CD-ROM/Methods in enzymology · 1995 · PMID 8524112
  not yet assessed
• The Mitogen-activated Protein Kinase Kinase MEK1 Stimulates a Pattern of Gene Expression Typical of the Hypertrophic Phenotype in Rat Ventricular Cardiomyocytes ↗

  Journal of Biological Chemistry · 1995 · PMID 7499296
  not yet assessed
• Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells ↗

  Cell · 1994 · PMID 7911739
  not yet assessed
• Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of hsp27 ↗

  Cell · 1994 · PMID 7923354
  not yet assessed
• Identification of the sites in MAP kinase kinase‐1 phosphorylated by p74raf‐1. ↗

  The EMBO Journal · 1994 · PMID 8157000
  not yet assessed
• Identification and characterization of a novel tyrosine kinase from megakaryocytes. ↗

  Journal of Biological Chemistry · 1994 · PMID 8288563
  not yet assessed
• Characterization of adhesive interactions between human endothelial cells and megakaryocytes. ↗

  Journal of Clinical Investigation · 1993 · PMID 8514851
  not yet assessed
• Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells ↗

  Blood · 1992 · PMID 1370386
  not yet assessed
• Effects of transforming growth factor beta on megakaryocytic cell fusion and endomitosis ↗

  The International Journal Of Cell Cloning · 1992 · PMID 1645030
  not yet assessed
• Effects of the stem cell factor, c-kit ligand, on human megakaryocytic cells ↗

  Blood · 1992
  not yet assessed
• The rapid assessment of nerve stumps ↗

  Journal of Bone and Joint Surgery - British Volume · 1991 · PMID 2071663
  not yet assessed
• Denatured muscle grafts for nerve repair. An experimental model of nerve damage in leprosy ↗

  Journal of Bone and Joint Surgery - British Volume · 1990 · PMID 2170419
  not yet assessed
• Major histocompatibility complex class II antigen expression in nerves in leprosy; an immunoelectronmicroscopical study. ↗

  PubMed · 1990 · PMID 2401839
  not yet assessed
• An immunoelectronmicroscopical study of the expression of major histocompatibility complex (MHC) class II antigens in guinea pig sciatic nerves following induction of intraneural mycobacterial granulomas ↗

  Journal of Neuroimmunology · 1989 · PMID 2754018
  not yet assessed
• Book Review: Pathogenesis of Leprosy and Related Diseases ↗

  Journal of the Royal Society of Medicine · 1989
  not yet assessed
• Book Review: Tuberculosis and Leprosy ↗

  Journal of the Royal Society of Medicine · 1989
  not yet assessed
• Nerve damage induced by mycobacterial granulomas in guinea pig sciatic nerves. ↗

  PubMed · 1988 · PMID 2842415
  not yet assessed