Chiara Auwerx

The share of this author’s assessed papers carrying a ⚑ flag. A concentration is a prompt for expert review — never, on its own, a determination about the person.

Collaborators, sized by shared output and coloured by their own reproducibility (green = high, red = low). Click a node to open their card. A pattern is a prompt for review, never a determination.

How this author’s assessed papers reproduced — the outcome of reproduction attempts, not a judgement of the person. Coverage is partial and grows over time.

Assessed papers (1)

• Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome.
  2021 L1 100/100

1 assessed by us (1 reproduced) · 44 not yet assessed — every PubMed paper on record, linked below.

• Mendelian randomization linking metabolites with enzymes reveals pathway regulation and therapeutic avenues ↗

  The American Journal of Human Genetics · 2026 · PMID 41650937
  not yet assessed
• Lipid transport is necessary for neocortical lamination ↗

  Genes & Diseases · 2026
  not yet assessed
• LiMA: Robust inference of molecular mediation from summary statistics ↗

  The American Journal of Human Genetics · 2026 · PMID 41512839
  not yet assessed
• Clinical, <i>in vitro,</i> and <i>in vivo</i> evidence of <i>WAPL</i> as a novel cohesinopathy gene and phenotypic driver of 10q22.3q23.2 genomic disorder ↗

  medRxiv · 2026 · PMID 41810376
  not yet assessed
• Clinical, in vitro, and in vivo evidence of WAPL as a cohesinopathy-associated gene and phenotypic driver of 10q22.3q23.2 genomic disorder ↗

  The American Journal of Human Genetics · 2026 · PMID 42431198
  not yet assessed
• Clinical, in vitro, and in vivo evidence of WAPL as a cohesinopathy-associated gene and phenotypic driver of 10q22.3q23.2 genomic disorder. ↗

  Open Access CRIS of the University of Bern · 2026
  not yet assessed
• Leveraging large-scale biobank EHRs to enhance pharmacogenetics of cardiometabolic disease medications ↗

  Nature Communications · 2025 · PMID 40133288
  not yet assessed
• MR-link-2: pleiotropy robust cis Mendelian randomization validated in three independent reference datasets of causality ↗

  Nature Communications · 2025 · PMID 40610416
  not yet assessed
• Mendelian randomization linking metabolites with enzymes reveals known and novel pathway regulation and therapeutic avenues ↗

  medRxiv · 2025
  not yet assessed
• Compounding of rare pathogenic copy-number variants and polygenic background is consistent with assortative mating ↗

  medRxiv · 2025
  not yet assessed
• Rare copy-number variants as modulators of common disease susceptibility ↗

  Genome Medicine · 2024 · PMID 38185688
  not yet assessed
• Breaking down causes, consequences, and mediating effects of telomere length variation on human health ↗

  Genome biology · 2024 · PMID 38760657
  not yet assessed
• The pleiotropic spectrum of proximal 16p11.2 CNVs ↗

  The American Journal of Human Genetics · 2024 · PMID 39332410
  not yet assessed
• Disentangling mechanisms behind the pleiotropic effects of proximal 16p11.2 BP4-5 CNVs ↗

  The American Journal of Human Genetics · 2024 · PMID 39332408
  not yet assessed
• MR-link-2: pleiotropy robust <i>cis</i> Mendelian randomization validated in four independent gold-standard datasets of causality ↗

  medRxiv · 2024
  not yet assessed
• Disentangling mechanisms behind the pleiotropic effects of proximal 16p11.2 BP4-5 CNVs ↗

  medRxiv · 2024
  not yet assessed
• Breaking down causes, consequences, and mediating effects of age-related telomere shortening on human health ↗

  medRxiv · 2024
  not yet assessed
• 65. DISENTANGLING MECHANISMS BEHIND THE PLEIOTROPIC EFFECTS OF PROXIMAL 16P11.2 BP4-5 COPY-NUMBER VARIANTS ↗

  European Neuropsychopharmacology · 2024
  not yet assessed
• Multi-layered genetic approaches to identify approved drug targets ↗

  Cell Genomics · 2023 · PMID 37492104
  not yet assessed
• Chromosomal deletions on 16p11.2 encompassing SH2B1 are associated with accelerated metabolic disease ↗

  Cell Reports Medicine · 2023 · PMID 37586323
  not yet assessed
• Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations ↗

  eLife · 2023 · PMID 36891970
  not yet assessed
• The impact of 22q11.2 copy-number variants on human traits in the general population ↗

  The American Journal of Human Genetics · 2023 · PMID 36706759
  not yet assessed
• Copy-number variants as modulators of common disease susceptibility ↗

  medRxiv · 2023
  not yet assessed
• Multi-layered genetic approaches to identify approved drug targets ↗

  medRxiv · 2023
  not yet assessed
• Author Correction: Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts ↗

  npj Genomic Medicine · 2023 · PMID 37225732
  not yet assessed
• Response to Bassett et al. ↗

  The American Journal of Human Genetics · 2023 · PMID 37419093
  not yet assessed
• The individual and global impact of copy-number variants on complex human traits ↗

  The American Journal of Human Genetics · 2022 · PMID 35240056
  not yet assessed
• From pharmacogenetics to pharmaco-omics: Milestones and future directions ↗

  Human Genetics and Genomics Advances · 2022 · PMID 35373152
  not yet assessed
• Quantifying the role of transcript levels in mediating DNA methylation effects on complex traits and diseases ↗

  Nature Communications · 2022 · PMID 36477627
  not yet assessed
• Omics-informed CNV calls reduce false-positive rates and improve power for CNV-trait associations ↗

  Human Genetics and Genomics Advances · 2022 · PMID 36035246
  not yet assessed
• Possible association of 16p11.2 copy number variation with altered lymphocyte and neutrophil counts ↗

  npj Genomic Medicine · 2022 · PMID 35715439
  not yet assessed
• Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• Omics-informed CNV calls reduce false positive rate and improve power for CNV-trait associations ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2022
  not yet assessed
• The impact of 22q11.2 copy number variants on human traits in the general population ↗

  medRxiv · 2022
  not yet assessed
• Author response: Exploiting the mediating role of the metabolome to unravel transcript-to-phenotype associations ↗

  2022
  not yet assessed
• Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome

  Nature Communications · 2021 · PMID 34561431
  L1 100/100
• Composite trait Mendelian randomization reveals distinct metabolic and lifestyle consequences of differences in body shape ↗

  Communications Biology · 2021 · PMID 34518635
  not yet assessed
• The individual and global impact of copy number variants on complex human traits ↗

  medRxiv · 2021
  not yet assessed
• Quantifying mediation between omics layers and complex traits ↗

  bioRxiv (Cold Spring Harbor Laboratory) · 2021
  not yet assessed
• GWAS summary statistics for waist-to-hip ratio and body principal components ↗

  Zenodo (CERN European Organization for Nuclear Research) · 2021
  not yet assessed
• GWAS summary statistics for waist-to-hip ratio and body principal components ↗

  Zenodo (CERN European Organization for Nuclear Research) · 2021
  not yet assessed
• GWAS summary statistics for waist-to-hip ratio and body principal components ↗

  Zenodo (CERN European Organization for Nuclear Research) · 2021
  not yet assessed
• Composite trait Mendelian Randomization reveals distinct metabolic and lifestyle consequences of differences in body shape ↗

  medRxiv · 2020
  not yet assessed
• Differentially expressed genes reflect disease-induced rather than disease-causing changes in the transcriptome ↗

  medRxiv · 2020
  not yet assessed
• Quantitative Proteome Landscape of the NCI-60 Cancer Cell Lines ↗

  iScience · 2019 · PMID 31733513
  not yet assessed