Corpus 1,277 assessed · 1,178 scored · 644 reproduced ≥75 · 170 flagged ·∅ 74/100
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GSE100242

GEO first seen 2017

A map of human circular RNAs in clinically-relevant tissues

Organism
Homo sapiens
Samples
24
Type
Other
Submitted
2017-06-20

Cellular circular RNAs (circRNAs) are generated by head-to-tail splicing and are present in all multicellular organisms studied so far. Recently, circRNAs have emerged as large class of RNA which can function as post-transcriptional regulators. It has also been shown that many circRNAs are tissue- and stage specifically expressed. Moreover, the unusual stability and expression specificity make circRNAs important candidates for clinical biomarker research. Here, we present a circRNA expression re...

Provenance — who produced it, who reused it

Linked to 2 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Philipp G MaassPetar GlažarSebastian MemczakGunnar DittmarIrene HollfingerLuisa SchreyerAisha V SauerOkan TokaAlessandro AiutiFriedrich C LuftNikolaus Rajewsky
Reused by

Deep data QC

91/100 · A

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured

Data type / assay
bulk-RNA-seq
Organism
Homo sapiens
Metrics (value · how obtained)
n content pct 0.003 measured
pct q20 bases 97.7 measured
pct q30 bases 95.2 measured
gc content pct 53.6 measured
mean read length 101 measured
mean base quality 36.5 measured
adapter content pct 0.12 measured
duplication rate pct 54.73 measured
How this grade was computed
Weighted mean of 4 scored metric(s) → 91/100

The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.

pct q30 bases 95.2 measured ×1 100%
mean base quality 36.5 measured ×0.6 100%
adapter content pct 0.12 measured ×0.4 100%
duplication rate pct 54.73 measured ×0.4 45%
QC cost 29 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0