Gene expression differences between adenocarcinoma and squamous cell carcinoma in human NSCLC
Non-small cell lung cancer (NSCLC) can be classified into the major subtypes adenocarcinoma (AC) and squamous cell carcinoma (SCC) subtypes. Although explicit molecular, histological and clinical characteristics have been reported for both subtypes, no specific therapy exists so far. However, the characterization of suitable molecular targets holds great promises to develop novel therapies in NSCLC. In the present study, global gene expression profiling of 58 human high grade NSCLC specimens rev...
Provenance — who produced it, who reused it
Linked to 39 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- EMT is associated with an epigenetic signature of ECM remodeling... 2019 · 148 cites
- Random generalized linear model: a highly accurate and interpret... 2013 · 145 cites
- Conservation of immune gene signatures in solid tumors and progn... 2016 · 126 cites
- Reconstruction of an Integrated Genome-Scale Co-Expression Netwo... 2013 · 116 cites
- Weighted Frequent Gene Co-expression Network Mining to Identify... 2012 · 86 cites
- Set7 mediated Gli3 methylation plays a positive role in the acti... 2016 · 72 cites
- Epithelial tumor suppressor ELF3 is a lineage-specific amplified... 2019 · 71 cites
32 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently