Transcriptome profiles of POM121-knockout prostate cancer cell lines
Nucleoporins are major constituents of nuclear pore complexes, molecular conglomerates embedded within the nuclear envelope that participate in bidirectional trafficking between nucleus and cytoplasm, chromatin silencing and organization, and transcriptional regulation . This functional vantage point is of utmost importance for fundamental cell processes such as intracellular signaling, cell migration, DNA repair and cell division, all of which can be impaired when the molecular identity of the...
Provenance — who produced it, who reused it
Linked to 1 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Nuclear Pores Promote Lethal Prostate Cancer by Increasing POM12... 2018 · 157 cites
Deep data QC
91/100 · AStandardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured
Human bulk RNA-seq with measured quality metrics (93.9% Q20, 85.8% Q30) across 560 samples, mean read length 100 bp, but instrument/platform metadata unavailable due to HTTP fetch error. Quality indicators suggest high-fidelity sequencing; utility for reuse depends on recovering experimental design and biological context from external sources.
The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0