Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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GSE107173

GEO first seen 2017

Triple vectors expand AAV transfer capacity in the retina

Organism
Homo sapiens
Samples
12
Type
Expression profiling by high...
Submitted
2017-11-20

Maddalena et al. showed that the limited DNA transfer capacity (~4.7kb) of adeno associated viral (AAV) vectors can be expanded up to 14kb with triple AAV vectors for the efficient expression of the therapeutic CDH23 (10.1kb) and ALMS1 (12.5kb) genes.

Provenance — who produced it, who reused it

Linked to 1 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
A MaddalenaP TornabeneA ManfrediM MutarelliD CacchiarelliA Auricchio
Reused by

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

Data type / assay
bulk-RNA-seq
Organism
Homo sapiens
Instrument
NextSeq 500
Platform
ILLUMINA
Read type
short-read
Files available
FASTQ (raw reads)
N numbers (samples, groups)
12 / 12 runs
Completeness
100%
Metrics (value · how obtained)
checksum ok yes reported
total bases 9839950609 reported
total reads 51391344 reported
supplementary file types TXT reported
QC cost 5 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently