Single-cell RNA sequencing resolves cellular heterogeneity throughout embryonic development of the thymus
This dataset consists of single-cell RNA-seq (Drop-seq) data from eight days of mouse thymus development. Samples span from embryonic day 12.5, when the thymus coalesces, until birth. They cover the whole thymus, including mesenchyme, endothelium, epithelium, thymocytes, and other lymphocytes. The dataset also includes Drop-seq data on Rag1-/- embryos and on fetal thymic organ cultures (control and a retinoic acid perturbation).
Provenance — who produced it, who reused it
Linked to 7 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- A cell atlas of human thymic development defines T cell repertoi... 2020 · 715 cites
- Inferring population dynamics from single-cell RNA-sequencing ti... 2019 · 124 cites
- Single-Cell RNA-Seq Mapping of Human Thymopoiesis Reveals Lineag... 2020 · 96 cites
3 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently