Developmental regulation of heterochromatin establishment at the maternal to zygotic transition
Heterochromatin has important functions in the organization of nuclear structure, the maintenance of genome integrity, and the regulation of gene expression programs1-3. Here, we demonstrate that the genome of the early zebrafish embryo is packaged in an atypical chromatin state that lacks features characteristic of heterochromatin. The heterochromatic histone modification, histone H3 lysine 9 trimethyl (H3K9me3), is undetectable in embryonic chromatin and embryonic nuclei are devoid of condense...
Provenance — who produced it, who reused it
Linked to 3 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
2 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently