GSE116239
GEOBulk RNA-seq of foamy and non-foamy intimal macrophages from ApoE -/- mouse
Macrophages in atherosclerotic aorta are major population in lesion and contributes to lesion formation by becoming foam cells. To investigate in vivo transcriptome profiles of those macrophages, we extracted foamy and non-foamy macrophages from atherosclerotic aorta using lipid probe-based flow cytometry sorting. Our data indicates that intima non-foamy and foamy macrophages show different mRNA expressions. Rather than non-foamy macrophages, foamy macrophages expressed more genes related to cho...
Provenance — who produced it, who reused it
Linked to 4 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
4 further papers cite this accession but reuse could not be confirmed.
What is in it (characterisation + QC)
Captured systematically as the reproduction roadmap touches each dataset: data type, N numbers, completeness, concordance with the paper, QC metrics.