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GSE116862

GEO first seen 2019

Chromatin structure dynamics during human cardiomyocyte differention reveals a role of HERV-H in demarcating TAD boundaries.

Organism
Callithrix jacchus; Pan paniscus; Pan troglodytes; Homo sapiens
Samples
115
Type
Expression profiling by high...
Submitted
2018-07-10

The three-dimensional chromatin architecture plays a critical role in the establishment of cell-type-specific gene regulatory networks in eukaryotic cells. How pluripotent stem cells (PSC) alter their chromatin architecture to direct cell fate specification remains to be elucidated. Here, using a human PSC cardiomyocyte differentiation model, we analyze the dynamic reorganization of chromatin structure and gene regulatory networks during key transitional stages of cardiomyocyte development. W...

Provenance — who produced it, who reused it

Linked to 10 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Bing RenNeil ChiYanxiao ZhangSebastian PreisslEugin DesticiTing LiHongbo YangJonathan GrinsteinAh-Yong LeeSora CheeZhen YeKaiyue MaNeil TedeschiSamantha KuanJennifer VeversSylvia Evans
Reused by

9 further papers cite this accession but reuse could not be confirmed.

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.

QC cost 23 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently