Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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GSE118409

GEO first seen 2018

Abundantly present miRNAs in milk-derived extracellular vesicles are conserved between mammals

Organism
Homo sapiens; Sus scrofa
Samples
3
Type
Non-coding RNA profiling by...
Submitted
2018-08-10

Mammalian milk is not only a source of nutrition for the newborn, but also contains various components that regulate further development. For instance, milk is an abundant source of microRNAs (miRNAs), which are evolutionary conserved small non-coding RNAs that are involved in post-transcriptional regulation of target mRNA. MiRNAs present in milk can occur in extracellular vesicles (EV), which are nanosized membrane vesicles released by many cell types as a means of intercellular communication....

Provenance — who produced it, who reused it

Linked to 1 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Martijn van HerwijnenMarca Wauben

Deep data QC

21/100 · F

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured

What this means
claude:haiku

Bulk RNA-seq of Sus scrofa (pig) with unavailable instrument details (HTTP error), but very concerning quality metrics showing poor base quality (72.1% Q30, 72.9% Q20, 35.6 bp read length, 24.973% N content). This dataset is severely quality-compromised and unsuitable for reliable transcript quantification without extensive remediation. Researchers should contact GEO to investigate the underlying cause of this extreme data degradation.

Data type / assay
bulk-RNA-seq
Organism
Sus scrofa
Metrics (value · how obtained)
n content pct 24.973 measured
pct q20 bases 72.9 measured
pct q30 bases 72.1 measured
gc content pct 41.7 measured
mean read length 35.6 measured
mean base quality 26.3 measured
adapter content pct 0.07 measured
duplication rate pct 94.03 measured
How this grade was computed
Weighted mean of 4 scored metric(s) → 21/100

The F grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.

pct q30 bases 72.1 measured ×1 11%
mean base quality 26.3 measured ×0.6 0%
adapter content pct 0.07 measured ×0.4 100%
duplication rate pct 94.03 measured ×0.4 0%
QC cost 27 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0