GSE119119

Transcriptome-wide analysis of TRIM21-mediated changes in gene expression after challenge with virus and antibody

Organism

Mus musculus

Samples

32

Type

Expression profiling by high...

Submitted

2018-08-28

We report that TRIM21 plays a crucial role in mediating antibody interference of adenovirus gene delivery and simultaneously initiates a transcriptional programme of immune genes.

Provenance — who produced it, who reused it

Linked to 2 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by

Maria BottermannLaurens M van TienenLeo C James

Reused by

Complement C4 Prevents Viral Infection through Capsid Inactivati... 2019 · 79 cites

1 further paper cites this accession but reuse could not be confirmed.

Deep data QC

85/100 · B

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured

Data type / assay

bulk-RNA-seq

Organism

Mus musculus

Metrics (value · how obtained)

n content pct 0.019 measured

pct q20 bases 99.5 measured

pct q30 bases 98.3 measured

gc content pct 50.8 measured

mean read length 50 measured

mean base quality 39.8 measured

adapter content pct 0.01 measured

duplication rate pct 71.33 measured

How this grade was computed

Weighted mean of 4 scored metric(s) → 85/100

The B grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.

pct q30 bases 98.3 measured ×1 100%

mean base quality 39.8 measured ×0.6 100%

adapter content pct 0.01 measured ×0.4 100%

duplication rate pct 71.33 measured ×0.4 8%

QC cost 25 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0