Corpus 1,284 assessed · 1,185 scored · 647 reproduced ≥75 · 173 flagged ·∅ 73.9/100
← Dataset search

GSE121382

GEO first seen 2020

Transcriptome Analysis of CircMRPS35 mediated mRNA expression profiles

Organism
Homo sapiens
Samples
6
Type
Expression profiling by high...
Submitted
2018-10-17

Purpose: To explore the mechanism of circMRPS35-mediated suppression of proliferation and invasion in gastric cancer. Methods: MGC-803 cells were transfected with control and SiRNA-circMRPS35, in triplicate. Total RNA was extracted using Trizol reagent.

Provenance — who produced it, who reused it

Linked to 1 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Shiming YangChangjiang Hu

Deep data QC

100/100 · A

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured

What this means
claude:haiku

Bulk RNA-seq of Homo sapiens with unavailable instrument details (HTTP error), but good quality (94% Q30, 150 bp read length, 2.49% adapter content) and confirmed GEO UID. This dataset enables human transcriptomics with long paired-end reads suitable for isoform resolution. The moderate adapter content suggests incomplete adapter trimming, requiring verification before downstream use.

Data type / assay
bulk-RNA-seq
Organism
Homo sapiens
Metrics (value · how obtained)
n content pct 0.011 measured
pct q20 bases 97.8 measured
pct q30 bases 94 measured
gc content pct 49.3 measured
mean read length 150 measured
mean base quality 38.8 measured
adapter content pct 2.49 measured
duplication rate pct 26.65 measured
How this grade was computed
Weighted mean of 4 scored metric(s) → 100/100

The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.

pct q30 bases 94 measured ×1 100%
mean base quality 38.8 measured ×0.6 100%
adapter content pct 2.49 measured ×0.4 97%
duplication rate pct 26.65 measured ×0.4 100%
QC cost 28 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0