GSE122380

Dynamic genetic regulation of gene expression during cellular differentiation

The impact of genetic regulatory elements on gene expression can change during differentiation and across cell types and environments. We mapped expression quantitative trait loci (eQTLs) throughout differentiation to elucidate the dynamics of genetic effects and the associated cell type specific mechanisms. To do so, we generated high resolution time-series RNA-sequencing data, capturing differentiation from induced pluripotent stem cells to cardiomyocytes with 16 time points in 19 human cell l...

Provenance — who produced it, who reused it

Linked to 6 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently