Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
← Dataset search

GSE12453

GEO first seen 2015

Origin and pathogenesis of lymphocyte-predominant Hodgkin lymphoma as revealed by global gene expression analysis

Organism
Homo sapiens
Samples
67
Type
Expression profiling by arra...
Submitted
2008-08-14

The pathogenesis of nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) and its relationship to other lymphomas are largely unknown. This is partly due to the technical challenge of analyzing its rare neoplastic L&H cells, which are dispersed in an abundant non-neoplastic cellular microenvironment. We performed a genome-wide expression study of microdissected lymphocytic and histiocytic (L&H) lymphoma cells in comparison to normal and other malignant B cells, which indicates a relationship o...

Provenance — who produced it, who reused it

Linked to 24 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Verena BruneEnrico TiacciInes PfeilClaudia DöringSusan EckerleCarel van NoeselWolfram KlapperBrunangelo FaliniAnja von HeydebreckDirk MetzlerAndreas BräuningerMartin-Leo HansmannRalf Küppers
Reused by

22 further papers cite this accession but reuse could not be confirmed.

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

Data type / assay
microarray-expr
Organism
Homo sapiens
Read type
not sequencing
Files available
CEL
Metrics (value · how obtained)
supplementary file types CEL reported
QC cost 2 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently