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RNAseq based trascript profilling of MCF7-xenograft mice treated with one of three CDK4/6 inhibitiors
Organism
Homo sapiens; Mus musculus
Samples
64
Type
Expression profiling by high...
Submitted
2019-01-09
We compare differences in gene expression induced after treating MCF7-xenograft mice with either ribociclib, palbociclib, or abemacicilb daily for 4 days.
Provenance — who produced it, who reused it
Linked to 2 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
Deposited / produced by
Marc HafnerCaitlin MillsSarah BoswellKartik Subramanian
Reused by
Deep data QC
100/100 · AStandardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured
Data type / assay
bulk-RNA-seq
Organism
Homo sapiens
Metrics (value · how obtained)
n content pct
0.002
measured
pct q20 bases
98.5
measured
pct q30 bases
97.7
measured
gc content pct
49.4
measured
mean read length
75
measured
mean base quality
35.2
measured
adapter content pct
0.32
measured
duplication rate pct
23.65
measured
How this grade was computed
Weighted mean of 4 scored metric(s) → 100/100
The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.
pct q30 bases
97.7
measured
×1
100%
mean base quality
35.2
measured
×0.6
100%
adapter content pct
0.32
measured
×0.4
100%
duplication rate pct
23.65
measured
×0.4
100%
QC cost
25 s compute
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0