Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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GSE126044

GEO first seen 2022

Genome-wide identification of differentially methylated promoters and enhancers associated with response to anti-PD-1 therapy in non-small cell lung cancer

Organism
Homo sapiens
Samples
16
Type
Expression profiling by high...
Submitted
2019-02-04

The purpose of this study is to compare transcriptional profiles of non-small-cell lung cancer between responder patients and non-responder patients during anti-PD-1 treatment.

Provenance — who produced it, who reused it

Linked to 37 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Jae-Won ChoMin H HongSang-Jun HaYoung-Joon KimByoung C ChoInsuk LeeHye R Kim
Reused by

36 further papers cite this accession but reuse could not be confirmed.

Deep data QC

100/100 · A

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured

Data type / assay
bulk-RNA-seq
Organism
Homo sapiens
Instrument
Illumina HiSeq 2500
Platform
ILLUMINA
Read type
short-read
Files available
FASTQ (raw reads)
N numbers (samples, groups)
16 / 16 runs
Completeness
100%
Metrics (value · how obtained)
checksum ok yes reported
total bases 126104837952 reported
total reads 624281376 reported
n content pct 0.004 measured
pct q20 bases 97.2 measured
pct q30 bases 95.3 measured
gc content pct 49.7 measured
mean read length 101 measured
mean base quality 37.6 measured
adapter content pct 1.34 measured
duplication rate pct 28.41 measured
supplementary file types TXT reported
How this grade was computed
Weighted mean of 4 scored metric(s) → 100/100

The A grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.

pct q30 bases 95.3 measured ×1 100%
mean base quality 37.6 measured ×0.6 100%
adapter content pct 1.34 measured ×0.4 100%
duplication rate pct 28.41 measured ×0.4 100%
QC cost 1.1 min compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0