Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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GSE126836

GEO first seen 2019

Single-cell multi-omic integration compares and contrasts features of brain cell identity

Organism
Homo sapiens; Mus musculus
Samples
50
Type
Expression profiling by high...
Submitted
2019-02-20

To flexibly model single-cell datasets, we developed LIGER, an algorithm and software package that delineates shared and dataset-specific features of cell identity. We applied it to four diverse and challenging analyses of human and mouse brain cells, the first two of which include newly generated single-cell transcriptome datasets for mouse and human regions. First, we determined region-specific and sexually dimorphic gene expression in the mouse bed nucleus of the stria terminalis (BNST). Sec...

Provenance — who produced it, who reused it

Linked to 7 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Joshua WelchVelina KozarevaAshley FerreiraCharles VanderburgCarly MartinEvan Macosko
Reused by

4 further papers cite this accession but reuse could not be confirmed.

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

Data type / assay
bulk-RNA-seq
Organism
Homo sapiens; Mus musculus
Instrument
Illumina NovaSeq 6000
Platform
ILLUMINA
Read type
short-read
Files available
FASTQ (raw reads), BAM/CRAM (aligned)
N numbers (samples, groups)
50 / 50 runs
Completeness
100%
Metrics (value · how obtained)
checksum ok yes reported
total bases 1891591269714 reported
total reads 21036170828 reported
supplementary file types CSV, MTX reported
QC cost 5 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently