Expression data from colorectal cancers
Wiskott-Aldrich syndrome (WAS) predisposes patients to leukemia and lymphoma. WAS is caused by mutations in the protein WASP which impair its interaction with the WIPF1 protein. Here, we aim to identify a module of WIPF1-coexpressed genes and to assess its use as a prognostic signature for colorectal cancer, glioma, and breast cancer patients. Two public colorectal cancer microarray data sets were used for discovery and validation of the WIPF1 co-expression module. Based on expression of the WIP...
Provenance — who produced it, who reused it
Linked to 47 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- FXR Regulates Intestinal Cancer Stem Cell Proliferation 2019 · 461 cites
- Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF... 2018 · 276 cites
- Tumor-selective proteotoxicity of verteporfin inhibits colon can... 2015 · 192 cites
- Molecular implications of MUC5AC-CD44 axis in colorectal cancer... 2020 · 157 cites
- Enhancing cancer‐associated fibroblast fatty acid catabolism wit... 2021 · 123 cites
42 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.