A large pool of actively cycling progenitors orchestrates self-renewal and injury repair of an ectodermal appendage
The classical model posits that a small number of quiescent stem cells (SCs) gives rise to proliferating transit-amplifying cells before terminal differentiation. However, recent evidence indicates that some tissues house multiple progenitor pools with distinct proliferative and differentiation potentials. Resolving the identity and spatial organization of these populations is therefore a fundamental requirement for understanding tissue renewal. Here, using a combination of single-cell RNA seque...
Provenance — who produced it, who reused it
Linked to 3 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- A large pool of actively cycling progenitors orchestrates self-r... 2019 · 110 cites
2 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently