Plant microRNAs in WT and SIDT1 KO mice liver
Animal microRNAs (which lack 2'-O-methyl modification) can be broken down at the terminal nucleotide by oxidation, while plant microRNAs (with 2'-O-methyl modification) are not affected. To gain additional sight into the role of SIDT1 in exogenous plant microRNAs absorption, we profiled oxidized smalll RNAs of liver from SIDT1 deficient mice and their wild type couterparts.
Provenance — who produced it, who reused it
Linked to 1 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- SIDT1-dependent absorption in the stomach mediates host uptake o... 2020 · 155 cites
Deep data QC
83/100 · BStandardized, field-standard QC computed by touching the data — every metric states how it was obtained · evidence: measured
This mouse miRNA-Seq from HiSeq 2000 totals 1.96 billion bases with very high quality (97.5% Q30). The dataset supports sensitive detection of small RNA expression in rodent samples.
The B grade is a transparent weighted average. Each metric below scored from 0–100% against the published bulk-RNA-seq thresholds, weighted by its importance; nothing is hidden or subjective.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0