The Molecular Anatomy of Mammalian Upper Lip and Primary Palate Fusion at Single Cell Resolution
The mammalian lip/primary palate form when coordinated growth and morphogenesis bring the nasal and maxillary processes into contact, the epithelia co-mingle, remodel and clear from the fusion site to allow mesenchyme continuity. Although several genes required for fusion have been identified, an integrated molecular and cellular description of the overall process is lacking. Here we employ single cell RNA sequencing of the developing mouse face to identify ectodermal, mesenchymal, and endotheli...
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1 further paper cites this accession but reuse could not be confirmed.
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