Predective Value of Prognosis-Related Gene Expression Study in Primary Bladder Cancer
This study aimed to identify the genetic signatures associated with disease prognosis in bladder cancer. We used 165 primary bladder cancer samples, 23 recurrent non-muscle invasive tumor tissues, 58 normal looking bladder mucosae surrounding cancer and 10 normal bladder mucosae for microarray analysis. Hierarchical clustering was used to stratify the prognosis-related gene classifiers. For validation, real-time reverse-transcriptase polymerase chain reaction (RT-PCR) of top-ranked 14 genes was...
Provenance — who produced it, who reused it
Linked to 196 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Intrinsic subtypes of high-grade bladder cancer reflect the hall... 2014 · 888 cites
- ALKBH5 Inhibited Cell Proliferation and Sensitized Bladder Cance... 2020 · 236 cites
- Comprehensive analysis of scRNA-Seq and bulk RNA-Seq reveals dyn... 2023 · 186 cites
- PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by... 2022 · 159 cites
- Large Scale Gene Expression Meta-Analysis Reveals Tissue-Specifi... 2016 · 156 cites
- RhoGDI2 suppresses lung metastasis in mice by reducing tumor ver... 2012 · 136 cites
- Identification of Biomarkers Correlated with the TNM Staging and... 2017 · 122 cites
- Multi-omics Integration Analysis Robustly Predicts High-Grade Pa... 2019 · 122 cites
- Unraveling a tumor type-specific regulatory core underlying E2F1... 2017 · 108 cites
- Biomolecular Events in Cancer Revealed by Attractor Metagenes 2013 · 105 cites
- Identification of key candidate genes and biological pathways in... 2018 · 104 cites
- The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Sup... 2023 · 93 cites
- Increased AURKA promotes cell proliferation and predicts poor pr... 2018 · 85 cites
- Systematic Analysis of Gene Expression Alteration and Co-Express... 2018 · 84 cites
- NUDT21 inhibits bladder cancer progression through ANXA2 and LIM... 2019 · 80 cites
- Integrated multiomics analysis and machine learning refine molec... 2023 · 79 cites
- Translation Initiation Factor eIF3b Expression in Human Cancer a... 2013 · 79 cites
- TGF-β-induced transgelin promotes bladder cancer metastasis by r... 2019 · 78 cites
62 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.