Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
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GSE141862

GEO first seen 2022

Single cell transcriptomics and chromatin accessibility in human fetal microglia

Organism
Homo sapiens
Samples
247
Type
Expression profiling by high...
Submitted
2019-12-11

Microglia, the myeloid cells of the central nervous system (CNS), are heterogeneous and exhibit distinct stages during mouse development; however, human microglia development is not elucidated. Here, single cell gene expression profiles of 15,782 human microglia and bulk chromatin profiles were assessed in 23 fetuses during development from gestational week (GW) 9 to 18. Microglia are highly heterogeneous at all developmental stages and exhibit transcriptional profiles similar to a phagocytic mi...

Provenance — who produced it, who reused it

Linked to 2 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Laura KrachtMalte BorggreweSharon EskandarNieske BrouwerSusana M Chuva de Sousa LopesJon D LamanSicco A ScherjonJelmer R PrinsSusanne M KooistraBart J Eggen
Reused by

1 further paper cites this accession but reuse could not be confirmed.

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

Data type / assay
ATAC-seq
Organism
Homo sapiens
Instrument
NextSeq 500
Platform
ILLUMINA
Read type
short-read
Files available
FASTQ (raw reads)
N numbers (samples, groups)
247 / 247 runs
Completeness
100%
Metrics (value · how obtained)
checksum ok yes reported
total bases 624459326808 reported
total reads 7615357644 reported
supplementary file types TXT reported
QC cost 15 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently