Expression data from 290 primary colorectal cancers
Samples were taken from colorectal cancers in surgically resected specimens in 290 colorectal cancer patients. The expression profiles were determined using Affymetrix Human Genome U133Plus 2.0 arrays. The training set of our prognosis classifier included the stage A and D samples. Validation used our stage B and C samples.
Provenance — who produced it, who reused it
Linked to 149 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- The consensus molecular subtypes of colorectal cancer 2015 · 5,246 cites
- Gene Expression Classification of Colon Cancer into Molecular Su... 2013 · 1,541 cites
- METTL14 suppresses proliferation and metastasis of colorectal ca... 2020 · 541 cites
- CDX2 as a Prognostic Biomarker in Stage II and Stage III Colon C... 2016 · 480 cites
- FXR Regulates Intestinal Cancer Stem Cell Proliferation 2019 · 461 cites
- lncRNA MIR100HG-derived miR-100 and miR-125b mediate cetuximab r... 2017 · 456 cites
- LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor... 2019 · 338 cites
- Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF... 2018 · 276 cites
- Cross-talk of four types of RNA modification writers defines tum... 2021 · 268 cites
- Contribution of serine, folate and glycine metabolism to the ATP... 2013 · 265 cites
- m<sup>6</sup>A regulator-based methylation modification patterns... 2020 · 261 cites
- Subtypes of primary colorectal tumors correlate with response to... 2012 · 257 cites
- DeepCC: a novel deep learning-based framework for cancer molecul... 2019 · 234 cites
- Tumor-selective proteotoxicity of verteporfin inhibits colon can... 2015 · 192 cites
- Significant Association of Oncogene YAP1 with Poor Prognosis and... 2014 · 162 cites
- A long non-coding RNA signature to improve prognosis prediction... 2014 · 159 cites
- TAZ Expression as a Prognostic Indicator in Colorectal Cancer 2013 · 157 cites
- The Interaction Between lncRNA SNHG6 and hnRNPA1 Contributes to... 2020 · 154 cites
- <i>miR-23a</i> Promotes the Transition from Indolent to Invasive... 2012 · 137 cites
- Prognostic genome and transcriptome signatures in colorectal can... 2024 · 134 cites
- Conservation of immune gene signatures in solid tumors and progn... 2016 · 126 cites
- Shortening of 3′UTRs Correlates with Poor Prognosis in Breast an... 2012 · 123 cites
- Recurrence-Associated Long Non-coding RNA Signature for Determin... 2018 · 110 cites
- Biomolecular Events in Cancer Revealed by Attractor Metagenes 2013 · 105 cites
- MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and f... 2020 · 105 cites
- AKT-dependent NOTCH3 activation drives tumor progression in a mo... 2020 · 104 cites
- Cancer-cell intrinsic gene expression signatures overcome intrat... 2017 · 99 cites
- Extracellular vesicle release from intestinal organoids is modul... 2019 · 97 cites
- Heat Shock Factor 1 Epigenetically Stimulates Glutaminase-1-Depe... 2018 · 95 cites
- Loss of the nuclear Wnt pathway effector TCF7L2 promotes migrati... 2020 · 95 cites
- XBP1 regulates the protumoral function of tumor-associated macro... 2021 · 90 cites
- Oridonin promotes endoplasmic reticulum stress via TP53-represse... 2023 · 90 cites
- Weighted Frequent Gene Co-expression Network Mining to Identify... 2012 · 86 cites
- ERK2-Dependent Phosphorylation of CSN6 Is Critical in Colorectal... 2015 · 82 cites
- An integrative analysis reveals functional targets of GATA6 tran... 2013 · 81 cites
45 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.