Gene expression data of human hepatocellular carcinoma (HCC)
We used Affymetrix microarray profiling to analyze gene expression patterns in healthy donor liver as well as tumor and paired non-tumor tissue of HCC patients.
Provenance — who produced it, who reused it
Linked to 465 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- WTAP facilitates progression of hepatocellular carcinoma via m6A... 2019 · 669 cites
- Inducing and exploiting vulnerabilities for the treatment of liv... 2019 · 428 cites
- Transcriptional addiction in cancer cells is mediated by YAP/TAZ... 2018 · 314 cites
- HCCDB: A Database of Hepatocellular Carcinoma Expression Atlas 2018 · 305 cites
- ALKBH5 suppresses malignancy of hepatocellular carcinoma via m6A... 2020 · 305 cites
- Urea Cycle Dysregulation Generates Clinically Relevant Genomic a... 2018 · 298 cites
- Identification of a bona fide microRNA biomarker in serum exosom... 2015 · 287 cites
- A Pharmacogenomic Landscape in Human Liver Cancers 2019 · 218 cites
- METTL5 stabilizes c‐Myc by facilitating USP5 translation to repr... 2023 · 208 cites
- Metabolism‐associated molecular classification of hepatocellular... 2020 · 195 cites
- Microenvironment characterization and multi-omics signatures rel... 2020 · 195 cites
- Upregulation of Heat Shock Proteins (HSPA12A, HSP90B1, HSPA4, HS... 2015 · 194 cites
- The RNA-binding protein RBM3 promotes cell proliferation in hepa... 2019 · 191 cites
- ZIC2-dependent OCT4 activation drives self-renewal of human live... 2015 · 173 cites
- A cluster of cooperating tumor-suppressor gene candidates in chr... 2012 · 169 cites
- Hepatic Hippo signaling inhibits protumoural microenvironment to... 2017 · 164 cites
- Oncogenic Activation of the RNA Binding Protein NELFE and MYC Si... 2017 · 161 cites
- Identification of the Consistently Altered Metabolic Targets in... 2017 · 156 cites
- LncRNA HAND2‐AS1 promotes liver cancer stem cell self‐renewal vi... 2019 · 145 cites
- A hypoxia-related signature for clinically predicting diagnosis,... 2020 · 144 cites
- Establishment and validation of a cholesterol metabolism-related... 2022 · 139 cites
- Downregulation of exosomal CLEC3B in hepatocellular carcinoma pr... 2019 · 138 cites
- Inactivation of Hippo Pathway Is Significantly Associated with P... 2015 · 124 cites
- Construction and comprehensive analysis of a ceRNA network to re... 2019 · 123 cites
- Genomic Predictors for Recurrence Patterns of Hepatocellular Car... 2014 · 120 cites
- POH1 deubiquitylates and stabilizes E2F1 to promote tumour forma... 2015 · 118 cites
- CCT3 acts upstream of YAP and TFCP2 as a potential target and tu... 2019 · 118 cites
- Identification of a four‐gene metabolic signature predicting ove... 2019 · 117 cites
- Identification of Energy Metabolism Genes for the Prediction of... 2020 · 116 cites
- Development of a macrophages-related 4-gene signature and nomogr... 2020 · 114 cites
- RBM15 promotes hepatocellular carcinoma progression by regulatin... 2021 · 111 cites
- Circular RNA cia-MAF drives self-renewal and metastasis of liver... 2021 · 109 cites
- MicroRNA-31 functions as a tumor suppressor by regulating cell c... 2015 · 108 cites
- Glucose deprivation–induced aberrant FUT1-mediated fucosylation... 2021 · 108 cites
- A Transcriptional and Metabolic Signature of Primary Aneuploidy... 2013 · 107 cites
- Large-scale analysis reveals a novel risk score to predict overa... 2018 · 104 cites
- Regulatory MiR‐148a‐ACVR1/BMP circuit defines a cancer stem cell... 2014 · 100 cites
- Krüppel-Like Factor 4, a Tumor Suppressor in Hepatocellular Carc... 2012 · 99 cites
- miR-192-5p Silencing by Genetic Aberrations Is a Key Event in He... 2018 · 98 cites
- SSRP1 Contributes to the Malignancy of Hepatocellular Carcinoma... 2016 · 97 cites
12 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.