Integrative approach for prioritizing cancer genes in sporadic colon cancer
The current multistep carcinogenesis models of colon cancer do not fully capture the genetic heterogeneity of the disease, which is additionally complicated by the presence of passenger and driver genetic alterations. The aim of the present study was to select in the context of this significant heterogeneity additional genes functionally related to colon cancer development. Methods: High-throughput copy number and gene expression data of 36 microsatellite stable sporadic colon cancers resected f...
Provenance — who produced it, who reused it
Linked to 12 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- A molecular mechanism that links Hippo signalling to the inhibit... 2012 · 375 cites
- TAK1 Inhibition Promotes Apoptosis in KRAS-Dependent Colon Cance... 2012 · 267 cites
- The long non-coding RNA CYTOR drives colorectal cancer progressi... 2018 · 162 cites
9 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently