Gene Expression Analysis of Stage I Endometrial Cancers
Global gene expression patterns associated with early stage endometrial cancer have been reported, but changes in molecular expression associated with tumor grade, depth of myometrial invasion, and non-endometrioid histology have not been previously elucidated. Our group hypothesized there are unique genetic events underlying early endometrial carcinogenesis. Ninety-two samples of pathologically reviewed stage I endometrial cancers (80 endometrioid and 12 serous) with a heterogeneous distribut...
Provenance — who produced it, who reused it
Linked to 74 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Long noncoding RNA NEAT1 drives aggressive endometrial cancer pr... 2019 · 163 cites
- Role of DNA Methylation and Epigenetic Silencing of HAND2 in End... 2013 · 156 cites
- Eleven genes associated with progression and prognosis of endome... 2019 · 104 cites
- MELK promotes Endometrial carcinoma progression via activating m... 2020 · 98 cites
- Long non-coding RNA DLEU2 drives EMT and glycolysis in endometri... 2021 · 87 cites
- PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 s... 2018 · 83 cites
- PADI2‐Catalyzed MEK1 Citrullination Activates ERK1/2 and Promote... 2021 · 76 cites
- ERRα promotes glycolytic metabolism and targets the NLRP3/caspas... 2023 · 73 cites
- MiR-424/503-Mediated Rictor Upregulation Promotes Tumor Progress... 2013 · 71 cites
- Epithelial tumor suppressor ELF3 is a lineage-specific amplified... 2019 · 71 cites
64 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently