Comparison of post-mortem tissue from brain BA10 region between schizophrenic and control patients.
Analysis of gene expression in two large schizophrenia cohorts identifies multiple changes associated with nerve terminal function. Schizophrenia is a severe psychiatric disorder with a world-wide prevalence of 1%. The pathophysiology of the illness is not understood, but is thought to have a strong genetic component with some environmental influences on aetiology. To gain further insight into disease mechanism, we used microarray technology to determine the expression of over 30 000 mRNA transc...
Provenance — who produced it, who reused it
Linked to 19 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Shared molecular neuropathology across major psychiatric disorde... 2018 · 1,155 cites
- Distinct longevity mechanisms across and within species and thei... 2023 · 149 cites
- Concerted Perturbation Observed in a Hub Network in Alzheimer’s... 2012 · 113 cites
- Genome-wide expression profiling of schizophrenia using a large... 2012 · 95 cites
- Highly interconnected genes in disease-specific networks are enr... 2012 · 81 cites
14 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently