Time Course of TGF-beta treatment of A549 lung adenocarcinoma cell line
Time Course of TGF-beta treatment of A549 lung adenocarcinoma cell line on Affymetrix HG_U133_plus_2 arrays; triplicate experiments. The goal of the experiment is to profile temporal gene expression changes during TGF-beta-induced epithelial-mesenchymal transition (EMT). During EMT cancer cells loose their epithelial specifc proteins and gain mesenchymal proteins to acquire migratory and invasive phenotype essential for metastasis. Human A549 lung adenocarcinoma cell line was treated with 5 n...
Provenance — who produced it, who reused it
Linked to 22 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Immunoproteasome deficiency is a feature of non-small cell lung... 2016 · 223 cites
- Genomic and microenvironmental heterogeneity shaping epithelial-... 2023 · 92 cites
- Immunosuppressive Traits of the Hybrid Epithelial/Mesenchymal Ph... 2021 · 83 cites
- The histone variant H2A.X is a regulator of the epithelial–mesen... 2016 · 82 cites
- A systematic approach identifies FOXA1 as a key factor in the lo... 2013 · 79 cites
17 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently