Whole-genome oligonucleotide expression analysis of papillary serous ovarian adenocarcinomas
To demonstrate the use of a whole-genome oligonucleotide array to perform expression profiling on a series of microdissected late-stage, high-grade papillary serous ovarian adenocarcinomas to establish a prognostic gene signature correlating with survival and to identify novel survival factors in ovarian cancer. Advanced stage papillary serous tumors of the ovary are responsible for the majority of ovarian cancer deaths, yet the molecular determinants modulating patient survival are poorly chara...
Provenance — who produced it, who reused it
Linked to 110 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Functional genomics identifies five distinct molecular subtypes... 2013 · 291 cites
- curatedOvarianData: clinically annotated data for the ovarian ca... 2013 · 213 cites
- Decoding critical long non-coding RNA in ovarian cancer epitheli... 2017 · 208 cites
- Identification of significant genes with poor prognosis in ovari... 2019 · 157 cites
- EZH2 Inhibition Sensitizes CARM1-High, Homologous Recombination... 2020 · 153 cites
- Angiogenic mRNA and microRNA Gene Expression Signature Predicts... 2012 · 150 cites
- Conservation of immune gene signatures in solid tumors and progn... 2016 · 126 cites
- The Long Noncoding RNA MALAT-1 is A Novel Biomarker in Various C... 2016 · 112 cites
- RNA demethylase ALKBH5 promotes ovarian carcinogenesis in a simu... 2020 · 112 cites
- Identification and molecular characterization of a new ovarian c... 2013 · 110 cites
- EZH2-mediated epigenetic silencing of TIMP2 promotes ovarian can... 2017 · 88 cites
- Epithelial tumor suppressor ELF3 is a lineage-specific amplified... 2019 · 71 cites
68 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.