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Quiescent human glioblastoma cancer stem cells mediate tumor initiation, expansion, and recurrence following chemotherapy
Organism
Homo sapiens; Mus musculus
Samples
36
Type
Expression profiling by high...
Submitted
2021-12-03
We performed single cell RNA sequencing with eight patient derived xenograft samples to identify quiescent cancer stem cells in glioblastoma. Additionally two samples treated with temozolomide was sequenced to examine the evolution of the cancer stem cells upon chemotherapeutics.
Provenance — who produced it, who reused it
Linked to 1 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
Deposited / produced by
Xuanhua P XieDan R LaksMungunsarnai GanboldLuis F Parada
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
Data type / assay
bulk-RNA-seq
Organism
Mus musculus; Homo sapiens
Instrument
Illumina HiSeq 4000
Platform
ILLUMINA
Read type
short-read
Files available
FASTQ (raw reads)
N numbers (samples, groups)
46 / 36 runs
Completeness
100%
Metrics (value · how obtained)
checksum ok
yes
reported
total bases
346369217033
reported
total reads
2940043523
reported
supplementary file types
CSV, TXT
reported
QC cost
6 s compute
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently