A gene expression profile of BRCAness that is associated with outcome in ovarian cancer
A gene expression profile of BRCAness was defined in publicly available expression data of 61 patients with epithelial ovarian cancer (34 patients with BRCA-1 or BRCA-2 mutations and 27 patients with sporadic disease). This dataset is publicly available at http://jnci.oxfordjournals.org/cgi/content/full/94/13/990/DC1 The BRCAness profile was correlated with outcome in 70 patients with epithelial ovarian cancer and known outcome data.
Provenance — who produced it, who reused it
Linked to 36 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Functional genomics identifies five distinct molecular subtypes... 2013 · 291 cites
- curatedOvarianData: clinically annotated data for the ovarian ca... 2013 · 213 cites
- The Long Noncoding RNA MALAT-1 is A Novel Biomarker in Various C... 2016 · 112 cites
33 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.