Modeling oncogenic signaling in colon tumors by multidirectional analyses of microarray data
Background. Most colorectal cancers (CRC) arise in a progression through adenoma to carcinoma phenotypes as a consequence of altered genetic information. Clinical progression of CRC may occur in parallel with distinctive signaling alterations. We designed multidirectional analyses integrating microarray-based data with biostatistics and bioinformatics to elucidate the signaling and metabolic alterations underlying CRC development in the adenoma-carcinoma sequence. Methodology/Principal Findin...
Provenance — who produced it, who reused it
Linked to 90 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- The consensus molecular subtypes of colorectal cancer 2015 · 5,246 cites
- Minfi: a flexible and comprehensive Bioconductor package for the... 2014 · 4,840 cites
- Cross-talk of four types of RNA modification writers defines tum... 2021 · 268 cites
- Contribution of serine, folate and glycine metabolism to the ATP... 2013 · 265 cites
- DeepCC: a novel deep learning-based framework for cancer molecul... 2019 · 234 cites
- RETRACTED ARTICLE: YAP1-induced MALAT1 promotes epithelial–mesen... 2018 · 214 cites
- Regulation of Tumor Initiation by the Mitochondrial Pyruvate Car... 2019 · 175 cites
- A single H/ACA small nucleolar RNA mediates tumor suppression do... 2019 · 141 cites
- The POU2F1-ALDOA axis promotes the proliferation and chemoresist... 2022 · 138 cites
- <i>miR-23a</i> Promotes the Transition from Indolent to Invasive... 2012 · 137 cites
- Prognostic genome and transcriptome signatures in colorectal can... 2024 · 134 cites
- Spermine synthase and MYC cooperate to maintain colorectal cance... 2020 · 116 cites
- MIR22HG acts as a tumor suppressor via TGFβ/SMAD signaling and f... 2020 · 105 cites
- Cell Cycle-Dependent Rho GTPase Activity Dynamically Regulates C... 2013 · 98 cites
- The effect of carbonic anhydrase IX on focal contacts during cel... 2013 · 96 cites
- TRIP13 promotes tumor growth and is associated with poor prognos... 2018 · 89 cites
- Molecular Profiling of Multiple Human Cancers Defines an Inflamm... 2013 · 86 cites
- TRIB2 functions as novel oncogene in colorectal cancer by blocki... 2018 · 85 cites
- Consensus molecular subtype classification of colorectal adenoma... 2018 · 84 cites
- An integrative analysis reveals functional targets of GATA6 tran... 2013 · 81 cites
- KIF20A promotes cellular malignant behavior and enhances resista... 2019 · 80 cites
- Epithelial tumor suppressor ELF3 is a lineage-specific amplified... 2019 · 71 cites
58 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently