A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma
A six-gene signature predicts survival of patients with localized pancreatic ductal adenocarcinoma Pancreatic ductal adenocarcinoma (PDAC), comprising over 90% of all pancreatic cancers, remains a lethal disease with an estimated 232,000 new cases, 227,000 deaths per year worldwide, and a less than 5% five-year survival rate. Currently the standard of care for the 20% of patients with localized disease is surgery followed by chemotherapy, and in some cases radiation. Unfortunately despite the us...
Provenance — who produced it, who reused it
Linked to 37 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- HOTAIR is a negative prognostic factor and exhibits pro-oncogeni... 2012 · 782 cites
- KrasG12D-Induced IKK2/β/NF-κB Activation by IL-1α and p62 Feedfo... 2012 · 520 cites
- Netrin G1 Promotes Pancreatic Tumorigenesis through Cancer-Assoc... 2020 · 208 cites
- Cancer associated fibroblast FAK regulates malignant cell metabo... 2020 · 166 cites
- Differential Expression of Metabolic Genes in Tumor and Stromal... 2012 · 99 cites
- Hippo pathway mediates resistance to cytotoxic drugs 2017 · 93 cites
- Deubiquitinating Enzyme USP9X Suppresses Tumor Growth via LATS K... 2017 · 89 cites
- Identification of key regulators of pancreatic cancer progressio... 2016 · 85 cites
- A reciprocal feedback between N6-methyladenosine reader YTHDF3 a... 2022 · 74 cites
28 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently