Clinical Significance of Osteoprotegerin Expression in Human Colorectal Cancer
Purpose: This study aimed to identify a novel biomarker or a target of treatment for colorectal cancer (CRC). Experimental Design: The expression profiles of cancer cells in 104 patients with CRC were examined using laser microdissection and oligonucleotide microarray analysis. Overexpression in CRC cells especially in patients with distant metastasis was a prerequisite to select candidate genes. The mRNA expression of candidate gene was investigated by quantitative reversetranscription polymera...
Provenance — who produced it, who reused it
Linked to 104 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- LncRNA SATB2-AS1 inhibits tumor metastasis and affects the tumor... 2019 · 338 cites
- Cross-talk of four types of RNA modification writers defines tum... 2021 · 268 cites
- Long noncoding RNA CRNDE promotes colorectal cancer cell prolife... 2017 · 161 cites
- Downregulation of MEIS1 mediated by ELFN1-AS1/EZH2/DNMT3a axis p... 2022 · 151 cites
- Long non-coding RNA RP11-468E2.5 curtails colorectal cancer cell... 2019 · 144 cites
- OMA1 reprograms metabolism under hypoxia to promote colorectal c... 2020 · 139 cites
- IgG Glycome in Colorectal Cancer 2016 · 135 cites
- SNORA21 – An Oncogenic Small Nucleolar RNA, with a Prognostic Bi... 2017 · 98 cites
- RETRACTED ARTICLE: LncRNA TUG1 promoted KIAA1199 expression via... 2018 · 92 cites
- Long non‐coding <scp>RNA FOXP</scp>4‐<scp>AS</scp>1 is an unfavo... 2016 · 87 cites
- TRIB2 functions as novel oncogene in colorectal cancer by blocki... 2018 · 85 cites
- An integrative analysis reveals functional targets of GATA6 tran... 2013 · 81 cites
- Long non-coding RNA SNHG17 is an unfavourable prognostic factor... 2017 · 76 cites
- The lncRNA ZFAS1 regulates lipogenesis in colorectal cancer by b... 2021 · 76 cites
- <p>Potential Prognostic and Diagnostic Values of CDC6, CDC... 2019 · 74 cites
65 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.