Corpus 1,272 assessed · 1,173 scored · 643 reproduced ≥75 · 168 flagged ·∅ 74.1/100
← Dataset search

GSE23371

GEO first seen 2020

Transcriptomes of monocyte-derived DCs stimulated with various compounds

Organism
Homo sapiens
Samples
12
Type
Expression profiling by arra...
Submitted
2010-08-02

Little is known about the early transcriptional events in innate immune signaling in immature and tolerogenic monocyte-derived dendritic cells (DCs), the professional antigen-presenting cells of our immune system. TLR ligands usually induce a proinflammatory transcriptional response, whereas IL10 and/or dexamethasone induce a more tolerogenic phenotype. We used Affymetrix microarrays to obtain detailed information underlying pro- and anti-inflammatory transcriptional responsesand transcriptional...

Provenance — who produced it, who reused it

Linked to 11 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.

Deposited / produced by
Bastiaan J JansenDagmar Eleveld-TrancikovaMaaike van Hout-KuijerGosse J AdemaIziah SamaHuynen Martijn
Reused by

9 further papers cite this accession but reuse could not be confirmed.

Deep data QC

metadata only · no data-level QC for this type

Standardized, field-standard QC computed by touching the data — every metric states how it was obtained

Data type / assay
microarray-expr
Organism
Homo sapiens
Read type
not sequencing
Files available
CEL
Metrics (value · how obtained)
supplementary file types CEL reported
QC cost 21 s compute

measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently