ChIP-Seq of chromatin marks at distal enhancers in Mouse Embryonic Stem Cells and adult tissues.
Enhancers are enriched by histone H3 lysine 4 mono methylation (H3K4me1). To gain insight into the relation between enhancers and developmental state, chromatin immunoprecipitation coupled with massive parallel sequencing (ChIP-seq) was performed in several cell types to determine the genome-wide binding targets of H3K4me1 and several other possible enhancer associated modifications.
Provenance — who produced it, who reused it
Linked to 10 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Divergent transcription of long noncoding RNA/mRNA gene pairs in... 2013 · 467 cites
- Effect of natural genetic variation on enhancer selection and fu... 2013 · 332 cites
- Ascl1 Coordinately Regulates Gene Expression and the Chromatin L... 2015 · 198 cites
- Zic2 Is an Enhancer-Binding Factor Required for Embryonic Stem C... 2015 · 117 cites
- Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Depend... 2017 · 107 cites
- Intragenic Enhancers Attenuate Host Gene Expression 2017 · 100 cites
4 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently