Stromal molecular signatures of breast and prostate cancer
Primary tumor growth induces host tissue responses that are believed to support and promote tumor progression. Identification of the molecular characteristics of the tumor microenvironment and elucidation of its crosstalk with tumor cells may therefore be crucial for improving our understanding of the processes implicated in cancer progression, identifying potential therapeutic targets, and uncovering stromal gene expression signatures that may predict clinical outcome. A key issue to resolve, t...
Provenance — who produced it, who reused it
Linked to 30 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- ITGB2-mediated metabolic switch in CAFs promotes OSCC proliferat... 2020 · 148 cites
- EMT is associated with an epigenetic signature of ECM remodeling... 2019 · 148 cites
- Sustained β‐catenin activity in dermal fibroblasts promotes fibr... 2014 · 113 cites
- Human bone marrow mesenchymal stem cells-derived microRNA-205-co... 2019 · 104 cites
- Epithelial tumor suppressor ELF3 is a lineage-specific amplified... 2019 · 71 cites
25 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently