Microarray gene-expression profiles of 45 matching pairs of pancreatic tumor and adjacent non-tumor tissues from 45 patients with pancreatic ductal adenocarcinoma
In order to identify biologically relevant tumor markers with prognostic significance, we set out to analyze gene expression profiling of tumor and adjacent non-tumor tissues from PDAC cases. We compared the microarray gene-expression profiles of 45 matching pairs of pancreatic tumor and adjacent non-tumor tissues. This data set were used to obtained genes that were differentially expressed and associated with survival. 51 genes were selected for further validation.
Provenance — who produced it, who reused it
Linked to 145 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- YTHDF1 links hypoxia adaptation and non-small cell lung cancer p... 2019 · 374 cites
- Identification of a Nine-Gene Signature and Establishment of a P... 2019 · 243 cites
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- Long noncoding RNA MIR31HG exhibits oncogenic property in pancre... 2015 · 149 cites
- Identification of candidate diagnostic and prognostic biomarkers... 2019 · 142 cites
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- MicroRNA-206 functions as a pleiotropic modulator of cell prolif... 2014 · 126 cites
- The RNA methyltransferase NSUN6 suppresses pancreatic cancer dev... 2021 · 124 cites
- The role of m6A-related genes in the prognosis and immune microe... 2020 · 118 cites
- Targeted CRISPR screening identifies PRMT5 as synthetic lethalit... 2020 · 113 cites
- Pancreatic cancer survival analysis defines a signature that pre... 2018 · 96 cites
- Development and Verification of the Hypoxia- and Immune-Associat... 2021 · 96 cites
- Hippo pathway mediates resistance to cytotoxic drugs 2017 · 93 cites
- Five key lncRNAs considered as prognostic targets for predicting... 2017 · 87 cites
- Identification of key regulators of pancreatic cancer progressio... 2016 · 85 cites
- CD73 acts as a prognostic biomarker and promotes progression and... 2020 · 84 cites
- PHD finger protein 1 (PHF1) is a novel reader for histone H4R3 s... 2018 · 83 cites
- The Insulin-Like Growth Factor 2 mRNA Binding Protein IMP2/IGF2B... 2019 · 77 cites
- Depletion of HDAC1, 7 and 8 by Histone Deacetylase Inhibition Co... 2018 · 74 cites
- Integrated transcriptomic analysis reveals hub genes involved in... 2019 · 72 cites
58 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently