Gene expression data for pathological stage I-II lung adenocarcinomas
Identification of genes up-regulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas. To elucidate molecular characteristics of lung adenocarcinomas (ADCs) with ALK mutations and those without EGFR, KRAS and ALK mutations, 226 primary lung ADCs of pathological stage I-II, examined for the status of EGFR, KRAS and ALK mutations, were subjected to genome-wide expression profiling, and genes up-regulated in lung ADCs with ALK mutations and those without EGFR, KRAS and ALK mutations...
Provenance — who produced it, who reused it
Linked to 432 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Minfi: a flexible and comprehensive Bioconductor package for the... 2014 · 4,840 cites
- SurvExpress: An Online Biomarker Validation Tool and Database fo... 2013 · 716 cites
- Identification of tumor immune infiltration-associated lncRNAs f... 2020 · 313 cites
- Single-cell transcriptional changes associated with drug toleran... 2021 · 271 cites
- Contribution of serine, folate and glycine metabolism to the ATP... 2013 · 265 cites
- Identification of CDK2-Related Immune Forecast Model and ceRNA i... 2021 · 247 cites
- Overall survival prediction of non-small cell lung cancer by int... 2020 · 192 cites
- A potential signature of eight long non-coding RNAs predicts sur... 2015 · 174 cites
- Silencing of Long Noncoding RNA <i>MIR22HG</i> Triggers Cell Sur... 2018 · 144 cites
- Predictability of human differential gene expression 2019 · 137 cites
- p53 mutants cooperate with HIF-1 in transcriptional regulation o... 2018 · 136 cites
- A clonal expression biomarker associates with lung cancer mortal... 2019 · 135 cites
- NPM1 Is a Prognostic Biomarker Involved in Immune Infiltration o... 2021 · 131 cites
- <scp>FAM</scp>83 family oncogenes are broadly involved in human... 2017 · 128 cites
- Conservation of immune gene signatures in solid tumors and progn... 2016 · 126 cites
- Profiling cancer testis antigens in non–small-cell lung cancer 2016 · 124 cites
- By integrating single-cell RNA-seq and bulk RNA-seq in sphingoli... 2023 · 122 cites
- RNA m6A reader YTHDF2 facilitates lung adenocarcinoma cell proli... 2021 · 120 cites
- High expression levels of pyrimidine metabolic rate–limiting enz... 2020 · 113 cites
- The Long Noncoding RNA MALAT-1 is A Novel Biomarker in Various C... 2016 · 112 cites
- A reference profile-free deconvolution method to infer cancer ce... 2020 · 111 cites
- Landscape and dynamics of single tumor and immune cells in early... 2021 · 110 cites
- HCP5 is a SMAD3-responsive long non-coding RNA that promotes lun... 2019 · 110 cites
- AIF-regulated oxidative phosphorylation supports lung cancer dev... 2019 · 110 cites
- Cancer stem-like properties and gefitinib resistance are depende... 2018 · 106 cites
- TAp73 opposes tumor angiogenesis by promoting hypoxia-inducible... 2014 · 105 cites
- DNA Repair Pathway Gene Expression Score Correlates with Repair... 2014 · 100 cites
- Super-enhancer hijacking LINC01977 promotes malignancy of early-... 2022 · 97 cites
- LncRNA LINC00472 regulates cell stiffness and inhibits the migra... 2020 · 96 cites
- A Robust 8-Gene Prognostic Signature for Early-Stage Non-small C... 2019 · 95 cites
- Identification of a Ferroptosis-Related LncRNA Signature as a No... 2021 · 93 cites
- Development and validation of a RNA binding protein-associated p... 2020 · 91 cites
- Integrative Analysis of NSCLC Identifies LINC01234 as an Oncogen... 2020 · 91 cites
- Cross-talk between cuproptosis and ferroptosis regulators define... 2023 · 90 cites
- Adenylate kinase 4 modulates oxidative stress and stabilizes HIF... 2019 · 88 cites
- TOP2A Promotes Lung Adenocarcinoma Cells' Malignant Progression... 2020 · 88 cites
- A large cohort study identifying a novel prognosis prediction mo... 2019 · 86 cites
- Sortilin limits EGFR signaling by promoting its internalization... 2017 · 84 cites
- Systematic Analysis of Gene Expression Alteration and Co-Express... 2018 · 84 cites
- FBXO11 promotes ubiquitination of the Snail family of transcript... 2015 · 83 cites
28 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.