Screening for Epigenetically Masked Genes in Colorectal Cancer using 5-aza-2’-deoxycytidine treatment, Microarray and Gene Expression Profile
Unearthing of silenced genes in colorectal cancer (CRC) is of great importance. We employed oligonucleotide microarray to find changes in global gene expression of five CRC cell lines. These were analyzed before and after treatment with the 5-aza-2'-Deoxycitidine. Expression of the responding genes was integrated with gene expression profiling generated by microarray analysis of matched colorectal tissue samples. Selected candidates were subjected to methylation-specific PCR (MSP) and real-time...
Provenance — who produced it, who reused it
Linked to 77 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Noncoding Effects of Circular RNA CCDC66 Promote Colon Cancer Gr... 2017 · 740 cites
- YTHDF1 Regulates Tumorigenicity and Cancer Stem Cell-Like Activi... 2019 · 292 cites
- N6-methyladenosine-induced circ1662 promotes metastasis of color... 2021 · 165 cites
- The long non-coding RNA CYTOR drives colorectal cancer progressi... 2018 · 162 cites
- Downregulation of MEIS1 mediated by ELFN1-AS1/EZH2/DNMT3a axis p... 2022 · 151 cites
- GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy... 2020 · 145 cites
- DDX39B drives colorectal cancer progression by promoting the sta... 2022 · 129 cites
- CCNA2 acts as a novel biomarker in regulating the growth and apo... 2018 · 107 cites
- Aberrant DNA methylation of WNT pathway genes in the development... 2016 · 81 cites
- <p>Potential Prognostic and Diagnostic Values of CDC6, CDC... 2019 · 74 cites
67 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently