Gene expression analysis of lung adenocarcinoma and matched adjacent non-tumor lung tissue
Gene expression profiling of 60 lung adenocarcinoma tumors and their matched histologically normal adjacent lung tissue samples were analyzed using Illumina HumanWG-6 v3.0 expression beadchip. We integrated these data with DNA methylation profiles of the same samples to identify potential DNA methylation regulated genes. Lung cancer is the leading cause of cancer death worldwide and adenocarcinoma is its most common histological subtype. Clinical and molecular evidence indicates that lung adenoc...
Provenance — who produced it, who reused it
Linked to 107 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Immunoproteasome deficiency is a feature of non-small cell lung... 2016 · 223 cites
- RETRACTED ARTICLE: N6-methyladenosine induced miR-143-3p promote... 2019 · 219 cites
- LPCAT1 promotes brain metastasis of lung adenocarcinoma by up-re... 2019 · 165 cites
- Predictability of human differential gene expression 2019 · 137 cites
- Metabox: A Toolbox for Metabolomic Data Analysis, Interpretation... 2017 · 112 cites
- Targeting HSP90 Inhibits Proliferation and Induces Apoptosis Thr... 2022 · 99 cites
- Overexpression of KIF20A confers malignant phenotype of lung ade... 2018 · 88 cites
- IGF2BP3 is an essential N6-methyladenosine biotarget for suppres... 2022 · 84 cites
- Feature Selection and Cancer Classification via Sparse Logistic... 2016 · 72 cites
71 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently