Gene expression profiles of human prefrontal cortex brain tissues
Dissecting the shared etiology of different diseases could benefit from a systematic search for associated molecules and their interactions. We investigated genome-wide disruptions in the co-regulation of genes in two neurodegenerative diseases, Alzheimer's or Huntington's disease (AD or HD), using expression profiles from postmortem prefrontal cortex samples of 624 demented patients and non-demented control individuals with matched genotype and clinical data. A meta-analysis based screen for ch...
Provenance — who produced it, who reused it
Linked to 45 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- A Multi-network Approach Identifies Protein-Specific Co-expressi... 2016 · 534 cites
- Prediction of Alzheimer’s disease using blood gene expression da... 2020 · 148 cites
- Identification and immunological characterization of cuproptosis... 2022 · 93 cites
- A Microglial Signature Directing Human Aging and Neurodegenerati... 2019 · 74 cites
41 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently