AMC colon cancer AJCCII
Profiling project of CRC patient material collected in the Academic Medical Center (AMC) in Amsterdam, The Netherlands. We focused on a set of 90 AJCC stage II patients that underwent intentionally curative surgery in the years 1997-2006 (AMC-AJCCII-90). Extensive medical records are kept from these patients and long-term clinical follow-up is available for the large majority. Both paraffin-embedded as well as fresh frozen tissue is available from all these patients for analysis.
Provenance — who produced it, who reused it
Linked to 77 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- The consensus molecular subtypes of colorectal cancer 2015 · 5,246 cites
- Gene Expression Classification of Colon Cancer into Molecular Su... 2013 · 1,541 cites
- Subtypes of primary colorectal tumors correlate with response to... 2012 · 257 cites
- DeepCC: a novel deep learning-based framework for cancer molecul... 2019 · 234 cites
- The long non-coding RNA CYTOR drives colorectal cancer progressi... 2018 · 162 cites
- Prognostic genome and transcriptome signatures in colorectal can... 2024 · 134 cites
- Recurrence-Associated Long Non-coding RNA Signature for Determin... 2018 · 110 cites
- A Novel lncRNA, LINC00460, Affects Cell Proliferation and Apopto... 2018 · 105 cites
- AKT-dependent NOTCH3 activation drives tumor progression in a mo... 2020 · 104 cites
- An integrative analysis reveals functional targets of GATA6 tran... 2013 · 81 cites
- Promoter capture Hi-C-based identification of recurrent noncodin... 2018 · 75 cites
66 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently
Scientific quality
Based on hands-on reproduction of the papers that use this dataset. A reproducible paper that stands on this data is positive evidence; a flagged one is a prompt to look closer — never a verdict on the dataset itself without the evidence.