Molecular characterisation of the multistep process of lung squamous carcinogenesis by gene expression profiling
We comprehensively characterized the gene expression alterations occurring during squamous lung cancer development. Fresh frozen human bronchial biopsies (N=122) at successive morphological stages of lung squamous carcinogenesis were obtained by fluorescence bronchoscopy and analyzed using gene expression microarrays.
Provenance — who produced it, who reused it
Linked to 18 papers in the literature. Roles are inferred factual signals (who deposited the data vs who reused it), with counts — never a judgement about any author.
- Atlas of clinically distinct cell states and ecosystems across h... 2021 · 341 cites
- Induction of APOBEC3 Exacerbates DNA Replication Stress and Chro... 2021 · 143 cites
- Transcriptomic and functional network features of lung squamous... 2018 · 136 cites
15 further papers cite this accession but reuse could not be confirmed.
Deep data QC
metadata only · no data-level QC for this typeStandardized, field-standard QC computed by touching the data — every metric states how it was obtained
No quantitative QC rubric exists for this data type yet, so it is deliberately left unscored — this is an honest "not applicable", not a poor rating.
measured = computed from the data · extrapolated/reported = derived or from the repository · dq-1.0 · provisional — verify independently